Mechanical switching and coupling between two dissociation pathways in a P-selectin adhesion bond

Models for the Specific Adhesion of Cells to Cells

1978 • 4,159 citations

Dynamic strength of molecular adhesion bonds

1997 • 2,444 citations

Direct observation of catch bonds involving cell-adhesion molecules

2003 • 968 citations

The reaction-limited kinetics of membrane-to-surface adhesion and detachment

1988 • 757 citations

Lifetime of the P-selectin-carbohydrate bond and its response to tensile force in hydrodynamic flow

1995 • 705 citations

Insights into the Molecular Basis of Leukocyte Tethering and Rolling Revealed by Structures of P- and E-Selectin Bound to SLeX and PSGL-1

2000 • 704 citations

Sensitive force technique to probe molecular adhesion and structural linkages at biological interfaces

1995 • 535 citations

Adhesion through L-selectin requires a threshold hydrodynamic shear

1996 • 456 citations

A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding

1995 • 435 citations

Selectins: lectins that initiate cell adhesion under flow

2002 • 409 citations

Force-mediated kinetics of single P-selectin/ligand complexes observed by atomic force microscopy

1998 • 393 citations

Adhesive Interactions of Leukocytes, Platelets, and the Vessel Wall during Hemostasis and Inflammation

2001 • 390 citations

The Kinetics of L-selectin Tethers and the Mechanics of Selectin-mediated Rolling

1997 • 355 citations

Threshold Levels of Fluid Shear Promote Leukocyte Adhesion through Selectins (CD62L,P,E)

1997 • 349 citations

Low Force Decelerates L-selectin Dissociation from P-selectin Glycoprotein Ligand-1 and Endoglycan

2004 • 245 citations

Chemically distinct transition states govern rapid dissociation of single L-selectin bonds under force

2001 • 222 citations

A Novel Glycosulfopeptide Binds to P-selectin and Inhibits Leukocyte Adhesion to P-selectin

1999 • 215 citations

Binding of Glycosulfopeptides to P-selectin Requires Stereospecific Contributions of Individual Tyrosine Sulfate and Sugar Residues

2000 • 204 citations

A Direct Comparison of Selectin-Mediated Transient, Adhesive Events Using High Temporal Resolution

1999 • 194 citations

Single Molecule Characterization of P-selectin/Ligand Binding

2003 • 182 citations

Dynamic Force Spectroscopy

2007 • 70 citations