Pharmacology and inotropic potential of forskolin in the human heart.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS

1949 • 19,979 citations

Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves.

1978 • 2,400 citations

Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts

1982 • 2,259 citations

Fundamentals of Enzyme Kinetics

1979 • 2,137 citations

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

1981 • 1,655 citations

Activation of adenylate cyclase by the diterpene forskolin does not require the guanine nucleotide regulatory protein.

1981 • 735 citations

Relationship between the beta-adrenergic receptor and adenylate cyclase.

1977 • 497 citations

(�)[125Iodo]cyanopindolol, a new ligand for ?-adrenoceptors: Identification and quantitation of subclasses of ?-adrenoceptors in guinea pig

1981 • 387 citations

Dopamine — Clinical Uses of an Endogenous Catecholamine

1974 • 357 citations

Catecholamine-specific desensitization of adenylate cyclase. Evidence for a multistep process.

1980 • 342 citations

Decreased Lymphocyte Beta-Adrenergic-Receptor Density in Patients with Heart Failure and Tolerance to the Beta-Adrenergic Agonist Pirbuterol

1981 • 331 citations

Fundamentals of Enzyme Kinetics

1980 • 241 citations

Stimulation of forskolin of intact S49 lymphoma cells involves the nucleotide regulatory protein of adenylate cyclase.

1982 • 240 citations

$beta;-Adrenergic function in heart muscle disease and heart failure

1985 • 187 citations

Drugs Five Years Later

1983 • 184 citations

Study of the normal and failing isolated human heart: Decreased response of failing heart to isoproterenol

1983 • 172 citations

The positive inotropic-acting forskolin, a potent adenylate cyclase activator.

1981 • 169 citations

Cyclic nucleotides and cardiac function.

1979 • 166 citations

Isoproterenol-Induced Cardiac Hypertrophy: Modifications in Characteristics of β-Adrenergic Receptor, Adenylate Cyclase, and Ventricular Contraction*

1979 • 119 citations

Myocardial Performance and Extracellular Ionized Calcium in a Severely Failing Human Heart

1983 • 95 citations

Positive inotropic and blood pressure lowering activity of a diterpene derivative isolated from Coleus forskohli: Forskolin.

1978 • 84 citations

Intermittent, continuous outpatient dobutamine infusion in the management of congestive heart failure

1983 • 81 citations

Pirbuterol, an oral beta-adrenergic receptor agonist, in the treatment of chronic cardiac failure.

1982 • 78 citations

Adenyl Cyclase and Myocardial Contractility

1970 • 74 citations

Binding characteristics of (+)-, (�)- and (-)-[125Iodo] cyanopindolol to guinea-pig left ventricle membranes

1982 • 73 citations

The human heart beta-adrenergic receptors. II. Coupling of beta 2-adrenergic receptors with the adenylate cyclase system.

1983 • 62 citations

Forskolin-activated adenylate cyclase. Inhibition by guanyl-5'-yl imidodiphosphate.

1983 • 59 citations

Genetic analysis of hormone-sensitive adenylate cyclase.

1980 • 59 citations

Histamine-mediated adenylate cyclase stimulation in human myocardium.

1982 • 59 citations

Effects of In Vivo β-Adrenoceptor Down-Regulation on Cardiac Responses to Prenalterol and Pirbuterol

1983 • 58 citations

The treatment of cardiogenic shock

1968 • 54 citations

Evidence for uncoupling of the beta receptor-adenylate cyclase complex.

1980 • 47 citations

Mechanism of Isoprenaline-Induced Refractoriness of the β-Adrenoceptor—Adenylate Cyclase Syste in Chick Embryo Cardiac Cells

1981 • 39 citations

Hemodynamic effects of prenalterol in patients with ischemic heart disease and congestive cardiomyopathy.

1982 • 35 citations

The treatment of cardiogenic shock

1967 • 21 citations