Association of Antioxidant Systems in the Protection of Human Fibroblasts Against Oxygen Derived Free Radicals

The serial cultivation of human diploid cell strains

1961 • 7,886 citations

Hydroperoxide metabolism in mammalian organs.

1979 • 5,821 citations

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Federation Proceedings

2009 • 3,950 citations

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

Oxygen free radicals and iron in relation to biology and medicine: Some problems and concepts

1986 • 2,052 citations

LABORATORY INVESTIGATION

1956 • 1,491 citations

Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage.

1978 • 1,117 citations

Lipid peroxidation damage to cell components.

1973 • 925 citations

Evidence that Peroxidation of Lysosomal Membranes Is Initiated by Hydroxyl Free Radicals Produced during Flavin Enzyme Activity

1973 • 663 citations

Lipid peroxidation and cellular damage in toxic liver injury.

1985 • 556 citations

Inactivation of key metabolic enzymes by mixed-function oxidation reactions: Possible implication in protein turnover and ageing

1983 • 467 citations

The Biology and Pathology of Oxygen Radicals

1978 • 437 citations

Oxygen Radicals, Hydrogen Peroxide, and Oxygen Toxicity

1976 • 430 citations

Antioxidant and co-antioxidant activity of vitamin C. The effect of vitamin C, either alone or in the presence of vitamin E or a water-soluble vitamin E analogue, upon the peroxidation of aqueous multilamellar phospholipid liposomes

1985 • 428 citations

The Role of Free Radical Reactions in Biological Systems

1976 • 374 citations

Aspects of Free Radical Reactions in Biological Systems: Aging

1980 • 306 citations

Glutathione Peroxidase Brought into Focus

1982 • 267 citations

Experimental Cell Research

1949 • 263 citations

Effect of glutathione peroxidase activity on lipid peroxidation in biological membranes

1976 • 262 citations

Hydrogen peroxide causes the fatal injury to human fibroblasts exposed to oxygen radicals.

1981 • 260 citations

Biochemical mechanisms accounting for the toxic action of oxygen on living organisms: The key role of superoxide dismutase

1978 • 249 citations

Comparative study of the enzymatic defense systems against oxygen-derived free radicals: The key role of glutathione peroxidase

1987 • 158 citations

Vitamin E as an Antioxidant in vitro and in vivo

1983 • 153 citations

The effect of oxygen tension on the growth and metabolism of WI‐38 cells

1976 • 151 citations

The effect of oxygen tension on the growth and metabolism of a mammalian cell

1961 • 99 citations

Modulation of oxidant lung injury by using liposome-entrapped superoxide dismutase and catalase.

1985 • 92 citations

Consecutive action of phospholipase A2 and glutathione peroxidase is required for reduction of phospholipid hydroperoxides and provides a convenient method to determine peroxide values in membranes

1985 • 87 citations

Improved system for capillary microinjection into living cells

1982 • 85 citations

Hydrogen peroxide detoxication by glutathione peroxidase and catalase in rat liver homogenates.

1968 • 84 citations

Molecular Pharmacology

1967 • 81 citations

Superoxide mediates the toxicity of paraquat for Chinese hamster ovary cells.

1986 • 78 citations

Superoxide dismutases: regularities and irregularities.

1983 • 70 citations

Scientific basis for the clinical use of superoxide dismutase

1986 • 66 citations

Superoxide dismutase induces differentiation in microplasmodia of the slime mold Physarum polycephalum

1988 • 51 citations

Shortening of the in vitro lifespan of human diploid fibroblasts exposed to hyperbaric oxygen☆

1983 • 37 citations

PHOTOHEMOLYSIS OF ERYTHROCYTES ENRICHED WITH SUPEROXIDE DISMUTASE, CATALASE AND GLUTATHIONE PEROXIDASE *

1986 • 25 citations

Importance of a threshold for error accumulation in cell degenerative processes. I. Modulation of the threshold in a model of free radical-induced cell degeneration

1990 • 24 citations

Quantitative study of natural antioxidant systems for cellular nitrofurantoin toxicity

1988 • 16 citations

What Determines the Degradation Rate of an Injected Protein?

1984 • 15 citations

Induction of DNA breakage and suppression of DNA synthesis by the OH radical generated in a Fenton-like reaction.

1986 • 13 citations