Identification of novel multi-transmembrane proteins from genomic databases using quasi-periodic structural properties

Basic local alignment search tool

1990 • 87,358 citations

A simple method for displaying the hydropathic character of a protein

1982 • 22,471 citations

Exploratory Data Analysis

1977 • 12,265 citations

Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids

2005 • 3,777 citations

Membrane protein structure prediction

1992 • 1,680 citations

Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes.

1990 • 1,542 citations

IDENTIFYING NONPOLAR TRANSBILAYER HELICES IN AMINO ACID SEQUENCES OF MEMBRANE PROTEINS

1986 • 1,495 citations

A Spatial Map of Olfactory Receptor Expression in the Drosophila Antenna

1999 • 1,156 citations

A Novel Family of Divergent Seven-Transmembrane Proteins

1999 • 1,110 citations

MECHANISMS OF OLFACTORY DISCRIMINATION: Converging Evidence for Common Principles Across Phyla

1997 • 1,074 citations

Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method

1997 • 1,043 citations

Prosite: a dictionary of sites and patterns in proteins

1992 • 952 citations

Methods for Statistical Data Analysis of Multivariate Observations.

1978 • 923 citations

Transmembrane helices predicted at 95% accuracy

1995 • 669 citations

Candidate Taste Receptors in Drosophila

2000 • 589 citations

Using the Fisher kernel method to detect remote protein homologies.

1999 • 408 citations

Splicing signals inDrosophila: intron size, information content, and consensus sequences

1992 • 380 citations

An algorithm for protein secondary structure prediction based on class prediction

1987 • 348 citations

Combining protein evolution and secondary structure

1996 • 204 citations

Sequences with ‘unusual’ amino acid compositions

1994 • 144 citations

Membrane proteins: from sequence to structure

1990 • 137 citations

PRINTS prepares for the new millennium

1999 • 129 citations

The PRINTS protein fingerprint database in its fifth year

1998 • 104 citations

Design of a discriminating fingerprint for G-protein-coupled receptors

1993 • 62 citations

The seven-transmembrane spanning topography of the Alzheimer disease-related presenilin proteins in the plasma membranes of cultured cells

1997 • 55 citations

Integrating database homology in a probabilistic gene structure model.

1997 • 45 citations

Sisyphus and prediction of protein structure

1997 • 43 citations

Multidrug Resistance Protein (Mdr)-alkaline Phosphatase Hybrids in Escherichia coli Suggest a Major Revision in the Topology of the C-terminal Half of Mdr

1995 • 43 citations

A statistical technique for predicting membrane protein structure

1985 • 41 citations

Hidden Markov Models of the G-Protein-Coupled Receptor Family

1994 • 33 citations

Preference functions for prediction of membrane-buried helices in integral membrane proteins

1998 • 32 citations

Quadratic Minimization of Predictors for Protein Secondary Structure

1993 • 29 citations

A flexible search technique based on generalized profiles.

1996 • 28 citations

‘TransMem’: a neural network implemented in Excel spreadsheets for predicting transmembrane domains of proteins

1997 • 26 citations

A predictor of transmembrane ?-helix domains of proteins based on neural networks

1996 • 25 citations

Olfactory Receptor Database: a database of the largest eukaryotic gene family

1999 • 24 citations

Olfactory Receptors: Transduction, Diversity, Human Psychophysics and Genome Analysis

2007 • 19 citations

Transmembrane segment prediction from protein sequence data.

1993 • 11 citations

Decoding the Signals of Membrane Protein Sequences

1994 • 8 citations

High-Throughput cDNA Screening Utilizing a Low Order Neural Network Filter

1996 • 6 citations