Antiviral Activity of Tumor Necrosis Factor (TNF) Is Mediated via p55 and p75 TNF Receptors

Mice lacking the tumour necrosis factor receptor 1 are resistant to IMF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes

1993 • 1,267 citations

Induction of apoptosis in mature T cells by tumour necrosis factor

1995 • 1,139 citations

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1996 • 947 citations

Soluble tumor necrosis factor (TNF) receptors are effective therapeutic agents in lethal endotoxemia and function simultaneously as both TNF carriers and TNF antagonists.

1993 • 837 citations

Tumour necrosis factors α and β inhibit virus replication and synergize with interferons

1986 • 726 citations

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

1993 • 573 citations

Tumor necrosis factors: developments during the last decade.

1996 • 473 citations

Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

1997 • 433 citations

Antiviral effects of recombinant tumour necrosis factor in vitro

1986 • 392 citations

Role of Lymphotoxin and the Type I TNF Receptor in the Formation of Germinal Centers

1996 • 386 citations

Antiviral defense in mice lacking both alpha/beta and gamma interferon receptors

1995 • 353 citations

Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence

1991 • 273 citations

T2 open reading frame from the shope fibroma virus encodes a soluble form of the TNF receptor

1991 • 215 citations

Mouse-Pox (Infectious Ectromelia of Mice): A Review

1949 • 199 citations

Recovery of immunodeficient mice from a vaccinia virus/IL-2 recombinant infection

1987 • 198 citations

Enhancement of TNF receptor p60-mediated cytotoxicity by TNF receptor p80: requirement of the TNF receptor-associated factor-2 binding site.

1997 • 183 citations

The T-cell-independent role of gamma interferon and tumor necrosis factor alpha in macrophage activation during murine cytomegalovirus and herpes simplex virus infections

1995 • 172 citations

Different roles for CD4+ and CD8+ T lymphocytes and macrophage subsets in the control of a generalized virus infection

1996 • 165 citations

Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: identification of a novel in vivo role for p75.

1995 • 163 citations

Therapeutic effect of anti-tumor necrosis factor-alpha antibody on the murine model of viral myocarditis induced by encephalomyocarditis virus.

1994 • 160 citations

Late phase inhibition of murine cytomegalovirus replication by synergistic action of interferon-gamma and tumour necrosis factor

1994 • 153 citations

Importance of interferons in recovery from mousepox

1993 • 146 citations

Dual role of the p75 tumor necrosis factor (TNF) receptor in TNF cytotoxicity.

1994 • 144 citations

Tumor necrosis factor as a mediator of inflammation in influenza A viral pneumonia

1995 • 134 citations

In vitro anti-human immunodeficiency virus activities of tumor necrosis factor-alpha and interferon-gamma.

1988 • 132 citations

Vaccinia virus homologues of the shope fibroma virus inverted terminal repeat proteins and a discontinuous orf related to the tumor necrosis factor receptor family

1991 • 130 citations

Participation of endogenous tumour necrosis factor in host resistance to cytomegalovirus infection

1993 • 103 citations

Antiviral activity of tumor necrosis factor is signaled through the 55-kDa type I TNF receptor [corrected].

1992 • 100 citations

The antiviral activity of immune CD8+ T cells is dependent on interferon-gamma.

1991 • 98 citations

Local production of tumor necrosis factor encoded by recombinant vaccinia virus is effective in controlling viral replication in vivo.

1991 • 93 citations

TNF receptor-2-triggered apoptosis is associated with the down-regulation of Bcl-xL on activated T cells and can be prevented by CD28 costimulation.

1997 • 79 citations

Ligand-induced Formation of p55 and p75 Tumor Necrosis Factor Receptor Heterocomplexes on Intact Cells

1997 • 77 citations

Adenovirus genes that modulate the sensitivity of virus‐infected cells to lysis by TNF

1993 • 56 citations

Phenotypic analysis of TNFR1-deficient mice and characterization of TNFR1-deficient fibroblasts in vitro.

1994 • 33 citations

Mousepox in inbred mice innately resistant or susceptible to lethal infection with ectromelia virus. IV. Studies with the Moscow strain

1988 • 20 citations

Effects of tumor necrosis factor-α treatment on mortality in murine cytomegalovirus-infected mice

1993 • 11 citations

Treatment with anti-tumor necrosis factor α does not influence the immune pathological response against lymphocytic choriomeningitis virus

1990 • 11 citations

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