Complete lack of NF-κB activity in IKK1 and IKK2 double-deficient mice: additional defect in neurulation

Function and Activation of NF-kappaB in the Immune System

1994 • 4,698 citations

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

1997 • 2,137 citations

IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation

1997 • 2,048 citations

The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation

1997 • 1,802 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK

1997 • 1,198 citations

Identification and Characterization of an IκB Kinase

1997 • 1,166 citations

How NF-κB is activated: the role of the IκB kinase (IKK) complex

1999 • 1,133 citations

Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB Activation

1998 • 1,070 citations

Gene Dosage–Dependent Embryonic Development and Proliferation Defects in Mice Lacking the Transcriptional Integrator p300

1998 • 984 citations

Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene

1999 • 978 citations

IKK-γ is an essential regulatory subunit of the IκB kinase complex

1998 • 950 citations

The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis

1999 • 922 citations

Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase

1999 • 827 citations

Binding and modulation of p53 by p300/CBP coactivators

1997 • 698 citations

Limb and Skin Abnormalities in Mice Lacking IKKα

1999 • 609 citations

Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice

1999 • 581 citations

NF-kappa B as a frequent target for immunosuppressive and anti-inflammatory molecules.

1997 • 576 citations

Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice.

2000 • 523 citations

IKK1-deficient mice exhibit abnormal development of skin and skeleton

1999 • 475 citations

NF-κB as a Frequent Target for Immunosuppressive and Anti-Inflammatory Molecules**This article was accepted for publication on 27 September 1996.

1997 • 472 citations

Severe liver degeneration and lack of NF-κB activation in NEMO/IKKγ-deficient mice

2000 • 469 citations

Roles of Nuclear Factor κB in Neuronal Survival and Plasticity

2000 • 465 citations

IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex

1999 • 333 citations

Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality

1999 • 303 citations

NF-κB activity in transgenic mice: developmental regulation and tissue specificity

1996 • 229 citations

Tumor necrosis factor alpha-induced phosphorylation of I kappa B alpha is a signal for its degradation but not dissociation from NF-kappa B.

1994 • 209 citations

p75-Mediated NF-κB Activation Enhances the Survival Response of Developing Sensory Neurons to Nerve Growth Factor

1999 • 193 citations