Caveolin-3 Knock-out Mice Develop a Progressive Cardiomyopathy and Show Hyperactivation of the p42/44 MAPK Cascade

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

Caveolins, Liquid-Ordered Domains, and Signal Transduction

1999 • 1,016 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.

1994 • 912 citations

Molecular Cloning of Caveolin-3, a Novel Member of the Caveolin Gene Family Expressed Predominantly in Muscle

1996 • 737 citations

A Requirement for Caveolin-1 and Associated Kinase Fyn in Integrin Signaling and Anchorage-Dependent Cell Growth

1998 • 720 citations

Cytoplasmic Signaling Pathways That Regulate Cardiac Hypertrophy

2001 • 696 citations

Expression of Caveolin-3 in Skeletal, Cardiac, and Smooth Muscle Cells

1996 • 692 citations

Endothelial Nitric Oxide Synthase Targeting to Caveolae

1996 • 670 citations

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family.

1996 • 566 citations

Cell-type and Tissue-specific Expression of Caveolin-2

1997 • 524 citations

Differential Targeting of β-Adrenergic Receptor Subtypes and Adenylyl Cyclase to Cardiomyocyte Caveolae

2000 • 514 citations

Dystroglycan-α, a dystrophin-associated glycoprotein, is a functional agrin receptor

1994 • 509 citations

Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade

1998 • 473 citations

Caveolin-3 Null Mice Show a Loss of Caveolae, Changes in the Microdomain Distribution of the Dystrophin-Glycoprotein Complex, and T-tubule Abnormalities

2001 • 450 citations

β–sarcoglycan: characterization and role in limb–girdle muscular dystrophy linked to 4q12

1995 • 448 citations

β–sarcoglycan (A3b) mutations cause autosomal recessive muscular dystrophy with loss of the sarcoglycan complex

1995 • 440 citations

Autosomal recessive limbgirdle muscular dystrophy, LGMD2F, is caused by a mutation in the δ–sarcoglycan gene

1996 • 422 citations

The dystrophin–glycoprotein complex, cellular signaling, and the regulation of cell survival in the muscular dystrophies

2001 • 414 citations

Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae

1996 • 378 citations

Caveolin‐mediated regulation of signaling along the p42/44 MAP kinase cascade in vivo

1998 • 371 citations

Disruption of the Sarcoglycan–Sarcospan Complex in Vascular Smooth Muscle

1999 • 370 citations

Caveolin Isoforms Differ in Their N-terminal Protein Sequence and Subcellular Distribution. IDENTIFICATION AND EPITOPE MAPPING OF AN ISOFORM-SPECIFIC MONOCLONAL ANTIBODY PROBE

1995 • 362 citations

Mutations in the human δ-sarcoglycan gene in familial and sporadic dilated cardiomyopathy

2000 • 349 citations

Caveolin-3 Associates with Developing T-tubules during Muscle Differentiation

1997 • 345 citations

Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, δ-sarcoglycan, in hamster: An animal model of disrupted dystrophin-associated glycoprotein complex

1997 • 302 citations

Microvascular spasm in the cardiomyopathic Syrian hamster: a preventable cause of focal myocardial necrosis.

1982 • 295 citations

γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

1998 • 287 citations

Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes

1997 • 275 citations

Up-regulation of Caveolin Attenuates Epidermal Growth Factor Signaling in Senescent Cells

2000 • 226 citations

Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolae

1997 • 221 citations

Depletion of Mitogen-Activated Protein Kinase Using an Antisense Oligodeoxynucleotide Approach Downregulates the Phenylephrine-Induced Hypertrophic Response in Rat Cardiac Myocytes

1996 • 209 citations

Disruption of the β-Sarcoglycan Gene Reveals Pathogenetic Complexity of Limb-Girdle Muscular Dystrophy Type 2E

2000 • 207 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 202 citations

Caveolin-3 Directly Interacts with the C-terminal Tail of β-Dystroglycan

2000 • 202 citations

Caveolin-deficient mice: insights into caveolar function human disease

2001 • 193 citations

M‐caveolin, a muscle‐specific caveolin‐related protein

1995 • 188 citations

Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophy

1996 • 165 citations

The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes

1995 • 159 citations

Evaluation of cardiac and respiratory involvement in sarcoglycanopathies

2001 • 153 citations

Activated Protein Kinase C Isoforms Target to Cardiomyocyte Caveolae

1999 • 148 citations

Bidirectional Signaling between Sarcoglycans and the Integrin Adhesion System in Cultured L6 Myocytes

1998 • 142 citations

Molecular Organization of Sarcoglycan Complex in Mouse Myotubes in Culture

1998 • 131 citations

Selective enhancement of beta-adrenergic receptor signaling by overexpression of adenylyl cyclase type 6: colocalization of receptor and adenylyl cyclase in caveolae of cardiac myocytes.

2000 • 129 citations

Adhesion-dependent tyrosine phosphorylation of β-dystroglycan regulates its interaction with utrophin

2000 • 126 citations

Impairment of Caveolae Formation and T-System Disorganization in Human Muscular Dystrophy with Caveolin-3 Deficiency

2002 • 126 citations

Activated Cardiac Adenosine A1 Receptors Translocate Out of Caveolae

2000 • 120 citations

Increased Number of Caveolae and Caveolin-3 Overexpression in Duchenne Muscular Dystrophy

1999 • 103 citations

Cell swelling-induced ATP release and gadolinium-sensitive channels

2002 • 97 citations

Accumulation of molecules involved in α1-adrenergic signal within caveolae: caveolin expression and the development of cardiac hypertrophy

2001 • 96 citations

Increased caveolin‐3 levels in mdx mouse muscles

1998 • 83 citations

Caveolin‐3 is not an integral component of the dystrophin glycoprotein complex

1998 • 82 citations

Ecto-ATPase Activity of α-Sarcoglycan (Adhalin)

1999 • 82 citations

Requirement of Caveolae Microdomains in Extracellular Signal‐Regulated Kinase and Focal Adhesion Kinase Activation Induced by Endothelin‐1 in Primary Astrocytes

1999 • 72 citations

The heart in limb girdle muscular dystrophy

1998 • 65 citations

Cardioprotective effects of verapamil on myocardial structure and function in a murine model of chronic Trypanosoma cruzi infection (Brazil Strain): an echocardiographic study

2002 • 54 citations

The Basic Helix-Loop-Helix Transcription Factors Myogenin and Id2 Mediate Specific Induction of Caveolin-3 Gene Expression during Embryonic Development

2000 • 51 citations

Prevention of hereditary cardiomyopathy in the syrian hamster with chronic verapamil therapy

1988 • 51 citations

Application of cardiac gated magnetic resonance imaging in murine Chagas' disease.

1999 • 43 citations

Type B Atrial Natriuretic Peptide Receptor in Cardiac Myocyte Caveolae

1997 • 43 citations

Dystrophin Associates With Caveolae of Rat Cardiac Myocytes

2000 • 34 citations

Expression of a Dystrophin–Sarcoglycan Complex in Serum-Deprived BC3H1 Cells and Involvement of α-Sarcoglycan in Substrate Attachment

1996 • 17 citations