Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia.

Metabolism of Isolated Fat Cells

1964 • 4,431 citations

Insulin stimulation of adipose tissue lipoprotein lipase. Use of the euglycemic clamp technique.

1982 • 276 citations

In vitro insulin resistance of human adipocytes isolated from subjects with noninsulin-dependent diabetes mellitus.

1983 • 249 citations

The existence of an optimal range of cytosolic free calcium for insulin-stimulated glucose transport in rat adipocytes.

1987 • 230 citations

Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects.

1987 • 228 citations

Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes. A new mechanism of insulin resistance.

1987 • 180 citations

Direct addition of insulin inhibits a high affinity Ca2+-ATPase in isolated adipocyte plasma membranes

1979 • 151 citations

Insulin Induces Progressive Insulin Resistance in Cultured Rat Adipocytes: Sequential Effects at Receptor and Multiple Postreceptor Sites

1986 • 119 citations

Insulin and Glyburide Increase Cytosolic Free-Ca2+ Concentration in Isolated Rat Adipocytes

1987 • 108 citations

The insulin receptor and calmodulin. Calmodulin enhances insulin-mediated receptor kinase activity and insulin stimulates phosphorylation of calmodulin.

1986 • 101 citations

Primary culture of isolated adipocytes. A new model to study insulin receptor regulation and insulin action.

1984 • 101 citations

INSULIN CONTROLLING CALCIUM DISTRIBUTION IN MUSCLE AND FAT CELLS

1974 • 80 citations

MODE OF INSULIN ACTION

1975 • 76 citations

Ability of insulin to increase calcium binding by adipocyte plasma membranes.

1976 • 76 citations

The role of calcium in the activation of the glucose transport system

1980 • 73 citations

Role of calcium ions in insulin action on hexose transport in L6 muscle cells

1984 • 51 citations

Hormone-receptor coupling and the molecular mechanism of insulin action in the adipocyte: A paradigm for Ca2+ homeostasis in the initiation of the insulin-induced metabolic cascade

1984 • 51 citations

Infusion of insulin impairs human adipocyte glucose metabolism in vitro without decreasing adipocyte insulin receptor binding

1984 • 43 citations

Calcium-dependence of insulin receptor phosphorylation

1983 • 40 citations

Direct effect of insulin on the binding of calmodulin to rat adipocyte plasma membranes.

1983 • 32 citations

Modulation by Calcium of the Insulin Action and of the Insulin-Like Effect of Ocytocin on Isolated Rat Lipocytes

1977 • 29 citations

Insulin and glyburide increase cytosolic free-Ca2+ concentration in isolated rat adipocytes

1987 • 26 citations

Long-term effect of insulin on glucose transport and insulin binding in cultured adipocytes from normal and obese humans with and without non-insulin-dependent diabetes.

1987 • 26 citations

Effects of the calcium ionophore A-23187 on the regulation of sugar transport in muscle

1980 • 24 citations

Effect of calcium on [125I]insulin binding to rat adipocytes

1978 • 20 citations

Is intracellular Ca²⁺ involved in insulin stimulation of sugar transport? Fact and prejudice

1984 • 20 citations

The Role of Calcium in the Transduction of Insulin Action

1985 • 17 citations

Influence of ambient glucose and insulin concentrations on adipocyte insulin binding

1983 • 16 citations

Insulin induces progressive insulin resistance in cultured rat adipocytes. Sequential effects at receptor and multiple postreceptor sites

1986 • 16 citations

Stimulation of glucose transport in rat adipocytes by calcium

1979 • 11 citations