Low density lipoprotein causes general cellular activation with increased phosphatidylinositol turnover and lipoprotein catabolism.

A RAPID METHOD OF TOTAL LIPID EXTRACTION AND PURIFICATION

1959 • 47,127 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUM

1955 • 8,846 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Changes in the levels of inositol phosphates after agonist-dependent hydrolysis of membrane phosphoinositides

1983 • 1,937 citations

The metabolism of very low density lipoprotein proteins I. Preliminary in vitro and in vivo observations

1972 • 1,831 citations

THE SMOOTH MUSCLE CELL

1971 • 1,571 citations

A new method of preparing gold probes for multiple-labeling cytochemistry.

1985 • 1,417 citations

Production of diglyceride from phosphatidylinositol in activated human platelets.

1979 • 727 citations

The Metabolism of Phosphoinositide-Derived Messenger Molecules

1986 • 717 citations

Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts.

1978 • 621 citations

Cytoplasmic free Ca²⁺ in human platelets: Ca²⁺ thresholds and Ca‐independent activation for shape‐change and secretion

1982 • 537 citations

Relationship between inositol polyphosphate production and the increase of cytosolic free Ca2+ induced by vasopressin in isolated hepatocytes.

1984 • 358 citations

Rapid decrease of phosphatidylinositol 4,5-bisphosphate in thrombin-stimulated platelets.

1982 • 323 citations

Platelet interaction with high and low density lipoproteins

1983 • 145 citations

Abnormalities of cholesterol-phospholipid composition in platelets and low-density lipoproteins of human hyperbetalipoproteinemia.

1977 • 138 citations

Platelet lipid composition and platelet aggregation in human liver disease

1981 • 129 citations

Platelet protein phosphorylation, elevation of cytosolic calcium, and inositol phospholipid breakdown in platelet activation induced by plasmin.

1986 • 124 citations

Colloidal gold--low density lipoprotein conjugates as membrane receptor probes.

1981 • 115 citations

Intracellular mechanisms in the activation of human platelets by low-density lipoproteins

1987 • 101 citations

Interaction of plasma lipoproteins with human platelets

1984 • 88 citations

Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase.

1985 • 78 citations

Uptake of latex particles by blood platelets: phagocytosis or sequestration?

1972 • 69 citations

The effect of hypercholesterolemia on guinea pig platelets, erythrocytes and megakaryocytes

1985 • 67 citations

Cholesterol exchange in platelets, erythrocytes and megakaryocytes

1985 • 64 citations

A search for the platelet secretory pathway using electron dense tracers.

1970 • 64 citations

Evidence for phosphorylation/dephosphorylation of rat liver acyl-CoA:cholesterol acyltransferase.

1983 • 58 citations

Vasopressin-induced calcium increases in smooth muscle cells from spontaneously hypertensive rats

1985 • 49 citations

Low density lipoprotein binding, internalization, and degradation in human adipose cells

1979 • 43 citations

Effects of EGF and thrombin on inositol‐containing phospholipids of cultured fibroblasts: Stimulation of phosphatidylinositol synthesis by thrombin but not EGF

1985 • 39 citations

Characterization of low density lipoprotein binding to human adipocytes and adipocyte membranes.

1984 • 32 citations

Measurement of Receptor Induced Changes in Intracellular Free Calcium in Human Platelets

1984 • 27 citations

Changes in very low and low density lipoproteins with dietary fat modification

1983 • 27 citations