Back to search

Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury

Data up to Jan 2025

Published2007
Citations993
References37

Total Citations Per Year

Abstract

References (37)

Multi-Organ, Multi-Lineage Engraftment by a Single Bone Marrow-Derived Stem Cell

2001 • 2,653 citations

Idiopathic Pulmonary Fibrosis: Diagnosis and Treatment

2000 • 2,535 citations

Mesenchymal stem cell engraftment in lung is enhanced in response to bleomycin exposure and ameliorates its fibrotic effects

2003 • 1,405 citations

Incidence and Prevalence of Idiopathic Pulmonary Fibrosis

2006 • 1,240 citations

Treatment of rheumatoid arthritis with recombinant human interleukin-1 receptor antagonist

1998 • 956 citations

The Dynamic in vivo Distribution of Bone Marrow-Derived Mesenchymal Stem Cells after Infusion

2001 • 927 citations

Transient expression of IL-1β induces acute lung injury and chronic repair leading to pulmonary fibrosis

2001 • 720 citations

Resolution of Lung Inflammation by CD44

2002 • 671 citations

Interleukin 1 receptor antagonist. A new member of the interleukin 1 family.

1991 • 589 citations

Bone marrow-derived cells as progenitors of lung alveolar epithelium

2001 • 555 citations

Characterization of mesenchymal stem cells isolated from murine bone marrow by negative selection

2003 • 483 citations

Tumor Necrosis Factor-α (TNF) Stimulates RANKL-induced Osteoclastogenesis via Coupling of TNF Type 1 Receptor and RANK Signaling Pathways

2001 • 476 citations

The Role of the Hyaluronan Receptor CD44 in Mesenchymal Stem Cell Migration in the Extracellular Matrix

2005 • 393 citations

Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis

1999 • 344 citations

Lung Cytokine Production in Bleomycin-Induced Pulmonary Fibrosis

1992 • 321 citations

Chemokines and tissue injury.

1995 • 303 citations

MicroSAGE Analysis of 2,353 Expressed Genes in a Single Cell‐Derived Colony of Undifferentiated Human Mesenchymal Stem Cells Reveals mRNAs of Multiple Cell Lineages

2001 • 268 citations

The Response of Human Epithelial Cells to TNF Involves an Inducible Autocrine Cascade

2006 • 212 citations

Interleukin 1 receptor antagonist (IL-1ra) prevents or cures pulmonary fibrosis elicited in mice by bleomycin or silica

1993 • 210 citations

Collagenase in the Lower Respiratory Tract of Patients with Idiopathic Pulmonary Fibrosis

1979 • 205 citations

Increased Risk of Fibrosing Alveolitis Associated with Interleukin-1 Receptor Antagonist and Tumor Necrosis Factor- α Gene Polymorphisms

2000 • 186 citations

Plasticity and Therapeutic Potential of Mesenchymal Stem Cells in the Nervous System

2005 • 185 citations

Mice Lacking the Type I Interleukin-1 Receptor Do Not Lose Bone Mass after Ovariectomy

1998 • 180 citations

Early and persistent alterations in the expression of interleukin-1 alpha, interleukin-1 beta and tumor necrosis factor alpha mRNA levels in fibrosis-resistant and sensitive mice after thoracic irradiation.

1996 • 175 citations

Early and Persistent Alterations in the Expression of Interleukin-1α, Interleukin-1β and Tumor Necrosis Factor α mRNA Levels in Fibrosis-Resistant and Sensitive Mice after Thoracic Irradiation

1996 • 156 citations

Mesenchymal Stem Cells and the Treatment of Cardiac Disease

2006 • 150 citations

Oxygen Radical Production by Alveolar Inflammatory Cells in Idiopathic Pulmonary Fibrosis

1990 • 136 citations

Cytokines and Pulmonary Fibrosis

1996 • 133 citations

Quantifying levels of transplanted murine and human mesenchymal stem cells in vivo by realtime PCR

2003 • 108 citations

Co‐expression of TNFα and IL‐1β in human acute pulmonary fibrotic diseases: An immunohistochemical analysis

1996 • 107 citations

Regulatory Effects of Interleukin (IL)-1, Interferon-β, and IL-4 on the Production of IL-1 Receptor Antagonist by Human Adipose Tissue

2004 • 107 citations

Influence of hypoxia on the domiciliation of Mesenchymal Stem Cells after infusion into rats: possibilities of targeting pulmonary artery remodeling via cells therapies?

2005 • 101 citations

Biological Activities Encoded by the Murine Mesenchymal Stem Cell Transcriptome Provide a Basis for Their Developmental Potential and Broad Therapeutic Efficacy

2005 • 93 citations

Therapeutic targeting of molecules involved in leukocyte–endothelial cell interactions

2006 • 91 citations

Platelet-activating factor contributes to acute lung leak in rats given interleukin-1 intratracheally

2000 • 48 citations

Phagocytes and Acute Lung Injury: Dual Roles For Interleukin‐1

1997 • 26 citations

Cytotoxicity of epigallocatechin-3-gallate to LNCaP cells in the presence of Cu2+

2005 • 15 citations

Cited By (0)

Loading...
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect… (2007) – Proceedings of the National Academy of Sciences | Metascience Observatory Explorer