The respiratory‐chain NADH dehydrogenase (complex I) of mitochondria

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression

1986 • 2,373 citations

Mitochondrial DNA Mutation Associated with Leber's Hereditary Optic Neuropathy

1988 • 2,368 citations

Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies

1988 • 1,806 citations

MITOCHONDRIAL COMPLEX I DEFICIENCY IN PARKINSON'S DISEASE

1989 • 1,717 citations

Sequence and gene organization of mouse mitochondrial DNA

1981 • 1,712 citations

THE MITOCHONDRIAL ELECTRON TRANSPORT AND OXIDATIVE PHOSPHORYLATION SYSTEM

1985 • 1,599 citations

Complete sequence of bovine mitochondrial DNA conserved features of the mammalian mitochondrial genome

1982 • 1,491 citations

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNALys mutation

1990 • 1,456 citations

Chloroplast gene organization deduced from complete sequence of liverwort Marchantia polymorpha chloroplast DNA

1986 • 1,456 citations

The Enzymes of Biological Membranes

1985 • 1,362 citations

MITOCHONDRIAL DNA MUTATIONS AS AN IMPORTANT CONTRIBUTOR TO AGEING AND DEGENERATIVE DISEASES

1989 • 1,179 citations

Prediction of the occurrence of the ADP-binding βαβ-fold in proteins, using an amino acid sequence fingerprint

1986 • 1,172 citations

Abnormalities of the electron transport chain in idiopathic parkinson's disease

1989 • 1,067 citations

The complete nucleotide sequence of the Xenopus laevis mitochondrial genome.

1985 • 741 citations

Deficiencies in Complex I subunits of the respiratory chain in Parkinson's disease

1989 • 735 citations

Deletions of mitochondrial DNA in Kearns‐Sayre syndrome

1988 • 730 citations

Redesign of the coenzyme specificity of a dehydrogenase by protein engineering

1990 • 727 citations

The complete nucleotide sequence of theRattus norvegicus mitochondrial genome: Cryptic signals revealed by comparative analysis between vertebrates

1989 • 523 citations

Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase

1985 • 517 citations

Evidence for a respiratory chain in the chloroplast

1982 • 472 citations

Iron-sulfur proteins,

1973 • 463 citations

Comparative aspects of quinol-cytochrome c/plastocyanin oxidoreductases

1983 • 396 citations

Deletions of mitochondrial DNA in Kearns‐Sayre syndrome

1988 • 354 citations

URF6, Last Unidentified Reading Frame of Human mtDNA, Codes for an NADH Dehydrogenase Subunit

1986 • 344 citations

Structure and function of energy-transducing membranes

1978 • 334 citations

Nucleotide sequence and gene organization of sea urchin mitochondrial DNA

1988 • 334 citations

Nucleotide sequence and expression of an operon in Escherichia coli coding for formate hydrogenylase components

1990 • 293 citations

Isolation of ubiquinol oxidase from Paracoccus denitrificans and resolution into cytochrome bc1 and cytochrome c-aa3 complexes.

1985 • 278 citations

NADH-ubiquinone oxidoreductases of the Escherichia coli aerobic respiratory chain

1987 • 262 citations

The Uniqueness of Plant Mitochondria

1989 • 258 citations

Two protons are pumped from the mitochondrial matrix per electron transferred between NADH and ubiquinone

1984 • 249 citations

Glucose dehydrogenase from Acinetobacter calcoaceticus

1979 • 246 citations

BACTERIAL ELECTRON TRANSPORT CHAINS

1988 • 233 citations

Evidence for a defect in NADH

1990 • 230 citations

Stoichiometry of H+ ejection and Ca2+ uptake coupled to electron transport in rat heart mitochondria.

1978 • 228 citations

Mitochondrial DNA mutations and neuromuscular disease

1989 • 216 citations

Cloning and nucleotide sequences of the genes for the subunits of NAD-reducing hydrogenase of Alcaligenes eutrophus H16

1990 • 209 citations

The Complete Nucleotide Sequence, Gene Organization, and Genetic Code of the Mitochondrial Genome of Paracentrotus lividus

1989 • 207 citations

Mechanism of the neurotoxicity of MPTP

1990 • 197 citations

Purification and characterization of a rotenone‐insensitive NADH: Q6 oxidoreductase from mitochondria of Saccharomyces cerevisiae

1988 • 193 citations

Photolabelling of a mitochondrially encoded subunit of NADH dehydrogenase with [³H]dihydrorotenone

1987 • 187 citations

Relationship between mitochondrial NADH-ubiquinone reductase and a bacterial NAD-reducing hydrogenase

1991 • 177 citations

New insights, ideas and unanswered questions concerning iron-sulfur cluster in mitochondia

1982 • 176 citations

A family of mitochondrial proteins involved in bioenergetics and biogenesis

1989 • 169 citations

Drosophila melanogaster mitochondrial DNA: gene organization and evolutionary considerations.

1988 • 169 citations

Integration of Mitochondrial Function

1988 • 165 citations

Proton Electrochemical Gradients and Energy-Transduction Processes

1982 • 163 citations

Sequences of six genes and several open reading frames in the kinetoplast maxicircle DNA of Leishmania tarentolae.

1984 • 162 citations

Studies on hexokinase: 1. The hexokinase activity of rat-brain extracts

1951 • 152 citations

Structure of NADH-Ubiquinone Reductase (Complex I)

1987 • 150 citations

An analysis of some thermodynamic properties of iron-sulphur centres in site I of mitochondria

1980 • 147 citations

Report of the committee on human mitochondrial DNA

1990 • 146 citations

A small isoform of NADH: ubiquinone oxidoreductase (complex I) without mitochondrially encoded subunits is made in chloramphenicol‐treated Neurospora crassa

1989 • 142 citations

Deficiency of the iron-sulfur clusters of mitochondrial reduced nicotinamide-adenine dinucleotide-ubiquinone oxidoreductase (complex I) in an infant with congenital lactic acidosis.

1984 • 138 citations

Nucleotide sequence ofAspergillus nidulansmitochondrial genes coding for ATPase subunit 6, cytochrome oxidase subunit 3, seven unidentified proteins, four tRNAs and L-rRNA

1982 • 135 citations

Normal Mitochondrial Genome in Brain from Patients with Parkinson's Disease and Complex I Defect

1990 • 131 citations

Studies on the electron transfer pathway, topography of iron-sulfur centers, and site of coupling in NADH-Q oxidoreductase.

1988 • 131 citations

Cytochromecoxidase in prokaryotes

1987 • 130 citations

Assembly of NADH: Ubiquinone reductase (complex I) in Neurospora mitochondria

1990 • 127 citations

The sequence of the gene for cytochromecoxidase subunit I, a frameshift containing gene for cytochromecoxidase subunit II and seven unassigned reading frames inTrypanosoma bruceimitochondrial maxi-cirle DNA

1984 • 124 citations

A homologue of the nuclear coded 49 kd subunit of bovine mitochondrial NADH-ubiquinone reductase is coded in chloroplast DNA.

1989 • 118 citations

The myxalamids, new antibiotics from Myxococcus xanthus (Myxobacterales) I. production, physico-chemical and biological properties, and mechanism of action.

1983 • 117 citations

Variable Genotype of Leber's Hereditary Optic Neuropathy Patients

1990 • 115 citations

EPR studies of iron-sulfur clusters in isolated subunits and subfractions of NADH-ubiquinone oxidoreductase.

1985 • 115 citations

Cloning, mapping, and sequencing of the gene encoding Escherichia coli quinoprotein glucose dehydrogenase

1990 • 111 citations

The inhibition site of MPP+, the neurotoxic bioactivation product of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine is near the Q-binding site of NADH dehydrogenase

1987 • 107 citations

Three-dimensional structure of NADH: Ubiquinone reductase (complex I) from Neurospora mitochondria determined by electron microscopy of membrane crystals

1987 • 106 citations

The ATP-to-oxygen stoichiometries of oxidative phosphorylation by rat liver mitochondria. An analysis of ADP-induced oxygen jumps by linear nonequilibrium thermodynamics.

1984 • 104 citations

Evidence of an ubisemiquinone radical(s) from the NADH-ubiquinone reductase of the mitochondrial respiratory chain.

1983 • 103 citations

Deletions of muscle mitochondrial DNA in mitochondrial myopathies: sequence analysis and possible mechanisms

1989 • 102 citations

Control of the rate of reverse electron transport in submitochondrial particles by the free energy

1977 • 101 citations

A comparison of the respiratory chain in particles from Paracoccus denitrificans and bovine heart mitochondria by EPR spectroscopy

1980 • 100 citations

Identification of the dicyclohexylcarbodiimide-binding subunit of NADH-ubiquinone oxidoreductase (Complex I).

1988 • 97 citations

psbG Is Not a Photosystem Two Gene but May Be an ndh Gene

1989 • 96 citations

Purification and characterization of NADH dehydrogenase complex from Paracoccus denitrificans

1986 • 95 citations

Genes encoding a subunit of respiratory NADH dehydrogenase (ND1) and a reverse transcriptase-like protein (RTL) are linked to ribosomal RNA gene pieces in Chlamydomonas reinhardtii mitochondrial DNA.

1988 • 94 citations

[57] Mitochondrial electron-transport inhibitors

1979 • 90 citations

Deficiency of subunits of complex I and mitochondrial encephalomyopathy

1988 • 90 citations

Coupling site I and the rotenone‐sensitive ubisemiquinone in tightly coupled submitochondrial particles

1990 • 88 citations

Capsaicin and its analogs inhibit the activity of NADH-coenzyme Q oxidoreductase of the mitochondrial respiratory chain

1989 • 87 citations

Proton/electron stoichiometry of mitochondrial complex I estimated from the equilibrium thermodynamic force ratio

1988 • 87 citations

Studies on the interaction of arylazido-beta-alanyl NAD+ with the mitochondrial NADH dehydrogenase.

1981 • 85 citations

Genes for cytochromecoxidase subunit I, URF2, and three tRNAs inDrosophilamitochondrial DNA

1983 • 82 citations

The mitochondrial URF1 gene in Neurospora crassa has an intron that contains a novel type of URF

1985 • 81 citations

Substrate Channeling of NADH and Binding of Dehydrogenases to Complex I

1989 • 80 citations

Thermodynamic limits to the ATP/site stoichiometries of oxidative phosphorylation by rat liver mitochondria.

1984 • 78 citations

Mitochondrial translation of subunits of the rotenone-sensitive NADH:ubiquinone reductase in Neurospora crassa.

1985 • 77 citations

The E35 stopper mutant of Neurospora crassa: precise localization of deletion endpoints in mitochondrial DNA and evidence that the deleted DNA codes for a subunit of NADH dehydrogenase.

1986 • 76 citations

Inhibition of NADH-ubiquinone reductase by N,N'-dicyclohexylcarbodiimide and correlation of this inhibition with the occurrence of energy-coupling site 1 in various organisms

1987 • 75 citations

Ubisemiquinone in the NADH‐ubiquinone reductase region of the mitochondrial respiratory chain

1989 • 74 citations

Characterization of the ndhC-psbG-ORF157/159 operon of maize plastid DNA and of the cyanobacterium Synechocystis sp. PCC6803

1989 • 72 citations

Purification and characterization of two types of NADH-quinone reductase from Thermus thermophilus HB-8

1988 • 72 citations

Iron-sulfur protein research

1987 • 72 citations

Molecular defects of NADH-ubiquinone oxidoreductase (Complex I) in mitochondrial diseases

1988 • 71 citations

Reconstitution of pyrroloquinoline quinone-dependent D-glucose oxidase respiratory chain of Escherichia coli with cytochrome o oxidase

1987 • 70 citations

Activation of site I redox-driven H+ pump by exogenous quinones in intact mitochondria.

1982 • 69 citations

Iron-Sulfur Protein Research

1987 • 69 citations

The same domain motif for ubiquinone reduction in mitochondrial or chloroplast NADH dehydrogenase and bacterial glucose dehydrogenase

1990 • 69 citations

Protein PSII-G. An additional component of photosystem II identified through its plastid gene in maize.

1986 • 69 citations

Mitochondrial NADH-ubiquinone reductase: complementary DNA sequences of import precursors of the bovine and human 24-kDa subunit

1989 • 67 citations

Mitochondrial NADH:ubiquinone reductase: complementary DNA sequence of the import precursor of the bovine 75-kDa subunit

1989 • 67 citations

Variable stoichiometry of proton pumping by the mitochondrial respiratory chain

1987 • 66 citations

H+/site, charge/site, and ATP/site ratios at coupling sites I and II in mitochondrial e- transport.

1979 • 66 citations

Sequence and arrangement of the genes for cytochromeb, URF1, URF4L, URF4, URF5, URF6 and five tRNAs inDrosophilamitochondrial DNA

1984 • 64 citations

Structure and expression of the overlapping ND4L and ND5 genes of Neurospora crassa mitochondria

1987 • 62 citations

Role of cysteine residues in the lac permease of Escherichia coli

1987 • 58 citations

Structural dependence of the inhibition of mitochondrial respiration and of NADH oxidase by 1-methyl-4-phenylpyridinium (MPP+) analogs and their energized accumulation by mitochondria.

1989 • 55 citations

Purification of NADH-ferricyanide dehydrogenase and NADH-quinone reductase from Escherichia coli membranes and their roles in the respiratory chain

1989 • 54 citations

Direct sequencing of deleted mitochondrial DNA in myopathic patients

1989 • 51 citations

The mitochondnal genome of Aspergillus nidulans contains reading frames homologous to the human URFs 1 and 4.

1983 • 48 citations

Identification of a stable ubisemiquinone and characterization of the effects of ubiquinone oxidation-reduction status on the Rieske iron-sulfur protein in the three-subunit ubiquinol-cytochrome c oxidoreductase complex of Paracoccus denitrificans.

1987 • 48 citations

Primary structure and expression of a nuclear-coded subunit of complex I homologous to proteins specified by the chloroplast genome

1990 • 46 citations

Energetics of ATP-driven reverse electron transfer from cytochrome c to fumarate and from succinate to NAD in submitochondrial particles

1984 • 45 citations

The pathway of electron transfer in NADH:Q oxidoreductase

1989 • 44 citations

Congenital deficiency of two polypeptide subunits of the iron-protein fragment of mitochondrial complex I.

1987 • 44 citations

Nucleotide sequence of the gene coding for quinoprotein glucose dehydrogenase from Acinetobacter calcoaceticus

1988 • 44 citations

Spectroscopic characterization of the number and type of iron-sulfur clusters in NADH:ubiquinone oxidoreductase.

1986 • 44 citations

Molecular cloning of subunits of complex I from Neurospora crassa. Primary structure and in vitro expression of a 22-kDa polypeptide.

1990 • 43 citations

EPR characterization of the iron-sulfur-containing NADH-ubiquinone oxidoreductase of the Escherichia coli aerobic respiratory chain

1989 • 43 citations

N-Arylazido-.beta.-alanyl-Nad+, a new nad+ photoaffinity analog. Synthesis and labeling of mitochondrial NADH dehydrogenase

1990 • 43 citations

The molecular morphology of bovine heart mitochondrial NADH—-ubiquinone reductase. Native disulfide-linked subunits and rotenone-induced conformational changes.

1985 • 41 citations

The 49 K subunit of NADH: ubiquinone reductase (complex I) from Neurospora crassa mitochondria: primary structure of the gene and the protein

1990 • 40 citations

Sequence homologies among mitochondrial DNA‐coded URF2, URF4 and URF5

1985 • 40 citations

Enhancement by tetraphenylboron of the interaction of the 1-methyl-4-phenylpyridinium ion (MPP+) with mitochondria

1989 • 40 citations

Upper and lower limits of the charge translocation stoichiometry of mitochondrial electron transport.

1987 • 39 citations

Genome organization ofArtemiamitochondrial DNA

1988 • 38 citations

Sequence analysis of mitochondrial DNA from Podospora anserina

1988 • 36 citations

Mitochondrial DNA of Chlamydomonas reinhardtii: the DNA sequence of a region showing homology with mammalian URF2

1984 • 36 citations

Studies on the structure of NADH:ubiquinone oxidoreductase complex: Topography of the subunits of the iron-sulfur flavoprotein component

1988 • 35 citations

New evidence for the dimeric nature of NADH:Q oxidoreductase in bovine-heart submitochondrial particles

1990 • 35 citations

Evidence for two independent pathways of electron transfer in mitochondrial NADH:Q oxidoreductase. I. Pre-steady-state kinetics with NADPH

1986 • 34 citations

The Primary Structure of Subunit II of NADH Dehydrogenase from Bovine‐Heart Mitochondria

1983 • 34 citations

Properties of mitochondria as a function of the growth stages of Neurospora crassa

1982 • 33 citations

Report of the committee on human mitochondrial DNA

1989 • 33 citations

Studies on the structure of NADH:ubiquinone oxidoreductase complex: Topography of the subunits of the iron-sulfur protein component

1989 • 32 citations

Puzzling subunits of mitochondrial cytochrome reductase

1990 • 32 citations

The site of synthesis of the iron-sulfur subunits of the flavoprotein and iron-protein fractions of human NADH dehydrogenase.

1988 • 31 citations

An unusual region of Paramedum mitochondrial DNA containing chloroplast-like genes

1989 • 29 citations

Analysis of NADH dehydrogenase proteins, ATPase subunit 9, cytochromeb, and ribosomal protein L14 encoded in the mitochondrial DNA ofParamecium

1990 • 29 citations

New 4-Hydroxypyridine and 4-Hydroxyquinoline Derivatives as Inhibitors of NADH-ubiquinone Reductase in the Respiratory Chain

1989 • 27 citations

Effects induced by rotenone during aerobic growth ofParacoccus denitrificans in continuous culture

1978 • 27 citations

Structure of the cloned Locusta migratoria mitochondrial genome: restriction mapping and sequence of its ND-1 (URF-1) gene

1987 • 26 citations

Nucleotide sequence of a protein coding region inChlamydomonas reinhardtümitochondrial DNA

1986 • 26 citations

Processing of mitochondrial RNA in Aspergillus nidulans

1989 • 25 citations

NN′-dicyclohexylcarbodi-imide-sensitivity of bovine heart mitochondrial NADH: ubiquinone oxidoreductase. Inhibition of activity and binding to subunits

1988 • 24 citations

Primary structure, in vitro expression and import into mitochondria of a 2921-KDA subunit of complex I from Neurospora crassa

1990 • 23 citations

Disproportionate Deficiency of Iron-Sulfur Clusters and Subunits of Complex I in Mitochondrial Encephalomyopathy

1989 • 23 citations

Piericiden A sensitivity, site 1 phosphorylation, and reduced nicotinamide adenine dinucleotide dehydrogenase during iron-limited growth of Candida utilis.

1975 • 23 citations

The structure of NADH:ubiquinone oxidoreductase from beef-heart mitochondria. Crystals containing an octameric arrangement of iron-sulphur protein fragments

1987 • 21 citations

Mitochondrial DNA of Chlamydomonas reinhardtii: the ND4 gene encoding a subunit of NADH dehydrogenase

1989 • 20 citations

Enzymic synthesis of papiliochrome II, a yellow pigment in the wings of papilionid butterflies

1989 • 20 citations

Sensitivity to NN'-dicyclohexylcarbodi-imide of proton translocation by mitochondrial NADH:ubiquinone oxidoreductase

1986 • 17 citations

cDNA of the 24 kDa subunit of the bovine respiratory chain NADH dehydrogenase: high sequence conservation in mammals and tissue-specific and growth-dependent expression

1989 • 16 citations

The amino acid sequence of the 24-kDa subunit, an iron-sulfur protein, of rat liver mitochondrial NADH dehydrogenase deduced from cDNA sequence

1988 • 16 citations

Identification of the subunits of bovine NADH dehydrogenase which are encoded by the mitochondrial genome

1990 • 15 citations

Regulation of the proton/electron stoichiometry of mitochondrial ubiquinol:cytochrome c reductase by the membrane potential

1991 • 14 citations

DCCD sensitivity of electron and proton transfer by NADH: ubiquinone oxidoreductase in bovine heart submitochondrial particles — a thermodynamic approach

1989 • 13 citations

Thermodynamic and steady-state-kinetic investigation of the effect of NN′-dicyclohexylcarbodi-imide on H+ translocation by the mitochondrial cytochrome bc1 complex

1985 • 10 citations

Nucleotide sequence of theAspergillus nidulansmitochondrial gene for subunit 5 of NADH dehydrogenase

1989 • 7 citations

The subunit I of the respiratory-chain NADH dehydrogenase from Cephalosporium acremonium: the evolution of a mitochondrial gene

1986 • 7 citations

Immunochemical probing of the structure and cofactor of NADH dehydrogenase from Paracoccus denitrificans

1987 • 7 citations

Structure and function of energy-transducing membranes : proceedings of a Workshop held in Amsterdam on August 10-13, 1977, in honour of E. C. Slater's 60th birthday

1977 • 7 citations

Iron-Sulfur Clusters in Mitochondrial Enzymes

1985 • 5 citations

Computer image analysis of two-dimensional crystals of beef heart NADH: Ubiquinone oxidoreductase fragments

1989 • 5 citations

Molecular analysis of Japanese gaucher disease

1989 • 4 citations

Book-Review - Magnetic Fields in Astrophysics

1984 • 3 citations

Inhibition of Bovine Heart Mitochondrial NADH — Ubiquinone Reductase by Tinopal AN, A Cationic Benzoxazole

1988 • 3 citations

Familial Mitochondrial Complex I Deficiency with an Abnormal Mitochondrial Encoded Protein

1989 • 2 citations