Identification of MAPKAP kinase 2 as a major enzyme responsible for the phosphorylation of the small mammalian heat shock proteins

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

1992 • 1,146 citations

Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II

1988 • 1,032 citations

Heat shock resistance conferred by expression of the human HSP27 gene in rodent cells.

1989 • 699 citations

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

1990 • 529 citations

Hsp90 chaperones protein folding in vitro

1992 • 514 citations

MAPKAP kinase-2; a novel protein kinase activated by mitogen-activated protein kinase.

1992 • 486 citations

Human HSP27 is phosphorylated at serines 78 and 82 by heat shock and mitogen-activated kinases that recognize the same amino acid motif as S6 kinase II.

1992 • 464 citations

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6

1991 • 442 citations

[37] Protein phosphatase-1 and protein phosphatase-2A from rabbit skeletal muscle

1988 • 418 citations

Characterization and purification of the small 28,000-dalton mammalian heat shock protein.

1987 • 263 citations

Substrate specificity of a multifunctional calmodulin-dependent protein kinase.

1985 • 243 citations

Phorbol ester, calcium ionophore, or serum added to quiescent rat embryo fibroblast cells all result in the elevated phosphorylation of two 28,000-dalton mammalian stress proteins.

1985 • 233 citations

Purification and characterization of a protein kinase from Xenopus eggs highly specific for ribosomal protein S6.

1986 • 207 citations

Identification of the phosphorylation sites of the murine small heat shock protein hsp25

1991 • 199 citations

Enhanced constitutive expression of the 27‐kDa heat shock proteins in heat‐resistant variants from chinese hamster cells

1988 • 128 citations

Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution.

1989 • 120 citations

Purification and characterisation of the insulin‐stimulated protein kinase from rabbit skeletal muscle; close similarity to S6 kinase II

1991 • 117 citations

Molecular cloning, sequencing and expression in Escherichia coli of the 25‐kDa growth‐related protein of Ehrlich ascites tumor and its homology to mammalian stress proteins

1989 • 106 citations

Phosphorylation of the small heat-shock protein is regulated by interleukin 1, tumour necrosis factor, growth factors, bradykinin and ATP

1991 • 91 citations

Over‐expression of the small heat‐shock protein, hsp25, inhibits growth of Ehrlich ascites tumor cells

1992 • 88 citations

Interleukin 1 and tumour necrosis factor increase phosphorylation of fibroblast proteins

1988 • 86 citations

The 27,000 daltons stress proteins are phosphorylated by protein kinase C during the tumor promoter-mediated growth inhibition of human mammary carcinoma cells

1988 • 65 citations

Rapid phosphorylation of a 27 kDa protein induced by tumor necrosis factor

1988 • 58 citations

Effect of proteases on the structure and activity of rabbit skeletal muscle glycogen synthetase

1979 • 28 citations