Neurobiology of Rett syndrome: a genetic disorder of synapse development

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

1999 • 4,776 citations

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

1998 • 3,363 citations

Synaptic density in human frontal cortex — Developmental changes and effects of aging

1979 • 2,587 citations

A progressive syndrome of autism, dementia, ataxia, and loss of purposeful hand use in girls: Rett's syndrome: Report of 35 cases

1983 • 1,481 citations

Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP

1995 • 1,197 citations

Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non-NMDA glutamate receptors.

1990 • 899 citations

Large-scale temporal gene expression mapping of central nervous system development

1998 • 647 citations

Involvement of basal ganglia transmitter systems in movement initiation

1998 • 216 citations

Neuropathology of Rett syndrome

1988 • 199 citations

Neonatal lesions of the basal forebrain cholinergic neurons result in abnormal cortical development

1988 • 199 citations

Neuroanatomy of Rett syndrome: A volumetric imaging study

1993 • 190 citations

Pervasive neuroanatomic abnormalities of the brain in three cases of Rett's syndrome

1995 • 172 citations

Cholinergic regulation of cortical development and plasticity. New twists to an old story.

1998 • 164 citations

Cytoskeletal Plasticity in Cells Expressing Neuronal Microtubule-Associated Proteins

1996 • 162 citations

Rett syndrome: A disorder affecting early brain growth

1997 • 132 citations

Morphological study of neocortical areas in Rett syndrome

1997 • 126 citations

Altered Development of Glutamate and GABA Receptors in the Basal Ganglia of Girls with Rett Syndrome

1999 • 124 citations

Development of amino acid receptors in frontal cortex from girls with Rett syndrome

1999 • 108 citations

Review of Rett Syndrome

1997 • 102 citations

N-Methyl-<scp>d</scp>-Aspartate Receptor Expression in the Nucleus Tractus Solitarii and Maturation of Hypoxic Ventilatory Response in the Rat

2000 • 89 citations

Polysomnographic characteristics of patients with Rett syndrome

1994 • 89 citations

High throughput analysis of gene expression in the human brain

2000 • 77 citations

Altered Cholinergic Function in the Basal Forebrain of Girls with Rett Syndrome

1999 • 77 citations

High levels of cerebrospinal fluid glutamate in Rett syndrome

1996 • 75 citations

Dendritic Cytoskeletal Protein Expression in Mental Retardation: An Immunohistochemical Study of the Neocortex in Rett Syndrome

2000 • 74 citations

Recent insights into hyperventilation from the study of Rett syndrome

1999 • 71 citations

Elevated CSF Glutamate in Rett Syndrome

1992 • 68 citations

Unusual EEG Theta Rhythms over Central Region in Rett Syndrome: Considerations of the Underlying Dysfunction

1997 • 58 citations

Newborn Basal Forebrain Lesions Disrupt Cortical Cytodifferentiation as Visualized by Rapid Golgi Staining

1991 • 57 citations

Postnatal changes in N‐methyl‐D‐aspartate receptor binding and stimulation by glutamate and glycine of [³H]‐MK‐801 binding in human temporal cortex

1993 • 52 citations

Rett Syndrome: 1H Spectroscopic Imaging at 4.1 Tesla

1999 • 50 citations

Dopaminergic D2 receptor SPECT imaging in Rett syndrome: increase of specific binding in striatum.

1993 • 48 citations

Rett syndrome: critical examination of clinical features, serial EEG and video-monitoring in understanding and management

1998 • 48 citations

Choline acetyltransferase activity and vesamicol binding in Rett syndrome and in rats with nucleus basalis lesions

1996 • 46 citations

Neurobiology of Rett Syndrome

1995 • 43 citations

Quantitative ¹ H MR spectroscopic imaging in early Rett syndrome

2000 • 38 citations

Neurophysiological observations on corticospinal projections to the upper limb in subjects with Rett syndrome.

1990 • 37 citations

Neurotrophic Factors in Cerebrospinal Fluid and Serum of Patients With Rett Syndrome

1998 • 35 citations

Decrease in benzodiazepine receptor binding in the brains of adult patients with Rett syndrome

1998 • 32 citations

Abnormal cortical excitability in Rett syndrome

1993 • 31 citations

Polysomnographic recordings of respiratory disturbances in Rett syndrome

1995 • 27 citations

Pathophysiology of Rett syndrome from the standpoint of early catecholamine disturbance.

1997 • 22 citations

The neuropathology of congenital hypothyroidism.

1972 • 22 citations

Observations on hand movements in Rett syndrome: a pilot study

1996 • 17 citations

Transcriptional repression by nuclear receptors: mechanisms and role in disease

2000 • 16 citations

Handwringing in Rett syndrome: A normal developmental stage

1992 • 14 citations

Effects of neonatal cholinergic basal forebrainlesions on excitatory amino acid receptors in neocortex

1998 • 12 citations

Neuropathological findings in the rubinstein-taybi syndrome.

1973 • 9 citations

Transcriptional repression by nuclear receptors: mechanisms and role in disease

2000 • 5 citations