Superoxide-dependent and -independent mechanisms of iron mobilization from ferritin by xanthine oxidase. Implications for oxygen-free-radical-induced tissue destruction during ischaemia and inflammation

Oxygen-Derived Free Radicals in Postischemic Tissue Injury

1985 • 5,488 citations

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Uric acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis.

1981 • 2,777 citations

Mechanisms of lipid peroxide formation in animal tissues

1966 • 1,291 citations

Superoxide radicals in feline intestinal ischemia

1981 • 1,213 citations

The Reduction of Cytochrome c by Milk Xanthine Oxidase

1968 • 1,201 citations

Reduction of the extent of ischemic myocardial injury by neutrophil depletion in the dog.

1983 • 1,168 citations

Iron-catalyzed hydroxyl radical formation. Stringent requirement for free iron coordination site.

1984 • 849 citations

Xanthine oxidase as a source of free radical damage in myocardial ischemia

1985 • 678 citations

Ferritin and superoxide-dependent lipid peroxidation.

1985 • 532 citations

Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of ‘free’ iron in biological systems by using bleomycin-dependent degradation of DNA

1981 • 469 citations

Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseases.

1984 • 392 citations

Studies on Milk Xanthine Oxidase

1969 • 376 citations

The pathophysiology of superoxide: roles in inflammation and ischemia

1982 • 368 citations

Xanthine oxidase type D (dehydrogenase) in the intestine and other organs of the rat

1972 • 201 citations

Responses of the ischemic myocardium to allopurinol

1971 • 183 citations

A comparison of the distribution and electron acceptor specificities of xanthine oxidase and aldehyde oxidase

1974 • 177 citations

THE MECHANISM OF IRON RELEASE FROM FERRITIN AS RELATED TO ITS BIOLOGICAL PROPERTIES

1955 • 151 citations

The effect of human serum transferrin and milk lactoferrin on hydroxyl radical formation from superoxide and hydrogen peroxide.

1984 • 147 citations

Effect of allopurinol on hemorrhagic shock

1969 • 140 citations

Mechanism of Release of Ferritin Iron In Vivo by Xanthine Oxidase1

1958 • 134 citations

Ferritin: an iron-storage molecule.

1977 • 118 citations

Effect of ferritin-containing fractions with different iron loading on lipid peroxidation

1983 • 114 citations

Lipid peroxidation of human erythrocyte ghosts induced by organic hydroperoxides

1983 • 102 citations

Lactoferrin-catalysed hydroxyl radical production. Additional requirement for a chelating agent

1983 • 96 citations

Structure and Function of Ferritin

1973 • 75 citations

RELATION OF URIC ACID METABOLISM TO RELEASE OF IRON FROM HEPATIC FERRITIN

1957 • 70 citations

Hepatic Xanthine Oxidase and Ferritin Iron in the Developing Rat

1965 • 53 citations

Liver xanthine dehydrogenase and iron mobilization

1982 • 52 citations

Xanthine oxidase induced depolymerization of hyaluronic acid in the presence of ferritin

1984 • 35 citations

HÆMOSIDEROSIS ASSOCIATED WITH XANTHINE OXIDASE INHIBITION

1966 • 31 citations

Inhibition of ferritin reduction by pyrazolo[3,4d]pyrimidines

1973 • 11 citations

Chronic allopurinol administration and iron storage in mice

1968 • 8 citations

Xanthine Oxidase Activity and Iron Storage in the Liver.

1961 • 7 citations