Enhanced Tumor Formation in Mice Heterozygous for Blm Mutation

A Dominant Mutation That Predisposes to Multiple Intestinal Neoplasia in the Mouse

1990 • 1,550 citations

Multiple Intestinal Neoplasia Caused by a Mutation in the Murine Homolog of the APC Gene

1992 • 1,510 citations

The Bloom's syndrome gene product is homologous to RecQ helicases

1995 • 1,371 citations

Bloom Syndrome

1993 • 529 citations

The Bloom's Syndrome Helicase Unwinds G4 DNA

1998 • 524 citations

The Bloom's syndrome gene product promotes branch migration of Holliday junctions

2000 • 492 citations

Cancer predisposition caused by elevated mitotic recombination in Bloom mice

2000 • 375 citations

Loss of Apc+ in intestinal adenomas from Min mice.

1994 • 373 citations

Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom’s syndrome gene

1998 • 199 citations

BLM Heterozygosity and the Risk of Colorectal Cancer

2002 • 194 citations

Evidence for chromosome instability in vivo in bloom syndrome: Increased numbers of micronuclei in exfoliated cells

1985 • 121 citations

Molecular evidence that homologous recombination occurs in proliferating human somatic cells.

1990 • 93 citations

Carrier Frequency of the Bloom SyndromeblmAshMutation in the Ashkenazi Jewish Population

1998 • 87 citations

Point mutations causing Bloom's syndrome abolish ATPase and DNA helicase activities of the BLM protein

1998 • 69 citations

The BLM helicase is necessary for normal DNA double-strand break repair.

2002 • 60 citations

Mapping of Multiple Intestinal Neoplasia (Min) to Proximal Chromosome 18 of the Mouse

1993 • 53 citations

High Frequency of a Common Bloom Syndrome Ashkenazi Mutation Among Jews of Polish Origin

1998 • 50 citations

Transfection of BLM into Cultured Bloom Syndrome Cells Reduces the Sister-Chromatid Exchange Rate toward Normal

1999 • 49 citations

Bloom's syndrome

1992 • 34 citations

Bloom's syndrome. XIX. Cytogenetic and population evidence for genetic heterogeneity

1996 • 28 citations

Numerous colonic adenomas in an individual with Bloom's syndrome

2001 • 22 citations

Chromosomal breakage in human spermatozoa, a heterozygous effect of the Bloom syndrome mutation.

1994 • 20 citations