Post-translational Regulation of Adipose Differentiation-related Protein by the Ubiquitin/Proteasome Pathway

A SIMPLE METHOD FOR THE ISOLATION AND PURIFICATION OF TOTAL LIPIDES FROM ANIMAL TISSUES

1957 • 63,238 citations

Proteasome inhibitors: valuable new tools for cell biologists

1998 • 1,453 citations

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

2001 • 718 citations

Adipose differentiation-related protein is an ubiquitously expressed lipid storage droplet-associated protein

1997 • 635 citations

Absence of perilipin results in leanness and reverses obesity in Leprdb/db mice

2000 • 577 citations

Mechanisms of lipid-body formation

1999 • 567 citations

Ubiquitination and deubiquitination: Targeting of proteins for degradation by the proteasome

2000 • 560 citations

Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation

2003 • 513 citations

Perilipin is located on the surface layer of intracellular lipid droplets in adipocytes.

1995 • 459 citations

Adipophilin is a specific marker of lipid accumulation in diverse cell types and diseases

1998 • 444 citations

Perilipin A Increases Triacylglycerol Storage by Decreasing the Rate of Triacylglycerol Hydrolysis

2000 • 428 citations

Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells

1999 • 425 citations

TIP47: A Cargo Selection Device for Mannose 6-Phosphate Receptor Trafficking

1998 • 386 citations

Functional Conservation for Lipid Storage Droplet Association among Perilipin, ADRP, and TIP47 (PAT)-related Proteins in Mammals, Drosophila, and Dictyostelium

2002 • 358 citations

Intracellular lipid particles of eukaryotic cells

2000 • 322 citations

TIP47 Associates with Lipid Droplets

2001 • 292 citations

The Degradation of Apolipoprotein B100 Is Mediated by the Ubiquitin-proteasome Pathway and Involves Heat Shock Protein 70

1997 • 285 citations

The Central Role of Perilipin A in Lipid Metabolism and Adipocyte Lipolysis

2004 • 260 citations

Lipid droplets: Proteins floating on a pool of fat

2001 • 253 citations

On the Control of Lipolysis in Adipocytes

1999 • 245 citations

Isolation of cDNAs for perilipins A and B: sequence and expression of lipid droplet-associated proteins of adipocytes.

1993 • 234 citations

Modulation of Hormone-sensitive Lipase and Protein Kinase A-mediated Lipolysis by Perilipin A in an Adenoviral Reconstituted System

2002 • 230 citations

Adipocyte Protein S3-12 Coats Nascent Lipid Droplets

2003 • 227 citations

Adipose Differentiation Related Protein (ADRP) Expressed in Transfected COS-7 Cells Selectively Stimulates Long Chain Fatty Acid Uptake

1999 • 214 citations

Functional Studies on Native and Mutated Forms of Perilipins

2003 • 203 citations

Structure of a Lipid Droplet Protein

2004 • 191 citations

Perilipins Are Associated with Cholesteryl Ester Droplets in Steroidogenic Adrenal Cortical and Leydig Cells

1995 • 182 citations

The murine perilipin gene: the lipid droplet-associated perilipins derive from tissue-specific, mRNA splice variants and define a gene family of ancient origin

2001 • 181 citations

Regulated Co-translational Ubiquitination of Apolipoprotein B100

1998 • 154 citations

Identification of Genes Potentially Involved in Rupture of Human Atherosclerotic Plaques

2001 • 139 citations

Post-translational Regulation of Perilipin Expression

1997 • 135 citations

Apoprotein B100 has a prolonged interaction with the translocon during which its lipidation and translocation change from dependence on the microsomal triglyceride transfer protein to independence

1998 • 120 citations

Stimulation of adipose differentiation related protein (ADRP) expression in adipocyte precursors by long-chain fatty acids

2000 • 108 citations

Induced expression of adipophilin mRNA in human macrophages stimulated with oxidized low‐density lipoprotein and in atherosclerotic lesions

1999 • 100 citations

Co-translational Interactions of Apoprotein B with the Ribosome and Translocon during Lipoprotein Assembly or Targeting to the Proteasome

2001 • 92 citations

Adipophilin is a sensitive marker for lipid loading in human blood monocytes

2001 • 86 citations

Ubiquitin-Dependent Signaling: The Role of Ubiquitination in the Response of Cells to Their Environment.

1999 • 83 citations

The measurement of ubiquitin and ubiquitinated proteins

1999 • 83 citations

Intracellular mechanisms regulating apoB-containing lipoprotein assembly and secretion in primary hamster hepatocytes

2000 • 73 citations

Induction of the Adipose Differentiation-Related Protein in Liver of Etomoxir-Treated Rats

1996 • 67 citations

Molecular cloning of a differentiation-related mRNA in the adipogenic cell line 1246.

1992 • 49 citations

Presecretory degradation of apolipoprotein[a] is mediated by the proteasome pathway

1999 • 49 citations

Adipose differentiation related protein: expression, purification of recombinant protein in Escherichia coli and characterization of its fatty acid binding properties

2000 • 44 citations

Translocation-arrested Apolipoprotein B Evades Proteasome Degradation via a Sterol-sensitive Block in Ubiquitin Conjugation

1999 • 31 citations

Apolipoprotein E in Macrophages and Hepatocytes Is Degraded via the Proteasomal Pathway

2001 • 19 citations