C-Reactive Protein as a Cardiovascular Risk Factor

The pathogenesis of atherosclerosis: a perspective for the 1990s

1993 • 10,730 citations

Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men

1997 • 5,442 citations

The Prognostic Value of C-Reactive Protein and Serum Amyloid A Protein in Severe Unstable Angina

1994 • 2,343 citations

Molecular Bases of the Acute Coronary Syndromes

1995 • 2,049 citations

Hemostatic Factors and the Risk of Myocardial Infarction or Sudden Death in Patients with Angina Pectoris

1995 • 1,807 citations

Production of C-reactive protein and risk of coronary events in stable and unstable angina

1997 • 1,515 citations

Chronic infections and coronary heart disease: is there a link?

1997 • 1,225 citations

Relation of C-Reactive Protein and Coronary Heart Disease in the MRFIT Nested Case-Control Study

1996 • 1,106 citations

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

1990 • 989 citations

Plasma Concentration of C-Reactive Protein and Risk of Developing Peripheral Vascular Disease

1998 • 987 citations

C Reactive protein and its relation to cardiovascular risk factors: a population based cross sectional study

1996 • 869 citations

Leukocyte capillary plugging in myocardial ischemia and reperfusion in the dog.

1983 • 845 citations

Relationship of C-Reactive Protein to Risk of Cardiovascular Disease in the Elderly

1997 • 838 citations

Phospholipids in animal eukaryotic membranes: transverse asymmetry and movement

1993 • 831 citations

Variability in the measurement of C-reactive protein in healthy subjects: implications for reference intervals and epidemiological applications

1997 • 814 citations

Para-aminosalicylic acid in tuberculosis; early results of clinical trials.

1947 • 797 citations

Elevated Levels of Interleukin-6 in Unstable Angina

1996 • 744 citations

Association of Helicobacter pylori and Chlamydia pneumoniae infections with coronary heart disease and cardiovascular risk factors

1995 • 609 citations

Elevation of C-reactive protein in “active” coronary artery disease

1990 • 592 citations

Prognostic Influence of Increased Fibrinogen and C-Reactive Protein Levels in Unstable Coronary Artery Disease

1997 • 529 citations

Secretory phospholipase A2 generates the novel lipid mediator lysophosphatidic acid in membrane microvesicles shed from activated cells

1995 • 523 citations

LONG-TERM EFFECTS OF INTRAVENOUS THROMBOLYSIS IN ACUTE MYOCARDIAL INFARCTION: FINAL REPORT OF THE GISSI STUDY

1987 • 521 citations

Cardiac Release of Cytokines and Inflammatory Responses in Acute Myocardial Infarction

1995 • 499 citations

Induction of phospholipase A2 gene expression in human hepatoma cells by mediators of the acute phase response

1991 • 406 citations

C-Reactive Protein Colocalizes With Complement in Human Hearts During Acute Myocardial Infarction

1997 • 395 citations

Measurement of serum C-reactive protein concentration in myocardial ischaemia and infarction.

1982 • 360 citations

C-Reactive Protein as a Predictor of Infarct Expansion and Cardiac Rupture After a First Q-Wave Acute Myocardial Infarction

1997 • 343 citations

Complement proteins C5b-9 induce vesiculation of the endothelial plasma membrane and expose catalytic surface for assembly of the prothrombinase enzyme complex.

1990 • 342 citations

COMPLEMENT ACTIVATION BY C‐REACTIVE PROTEIN COMPLEXES*

1982 • 288 citations

Serum C-reactive protein concentration in acute myocardial infarction and its relationship to mortality during 24 months of follow-up in patients under thrombolytic treatment

1996 • 270 citations

Reduction by Cobra Venom Factor of Myocardial Necrosis after Coronary Artery Occlusion

1978 • 264 citations

Phospholipase A2 enzymes: regulation and inhibition

1993 • 253 citations

Symptoms of chronic bronchitis and the risk of coronary disease

1996 • 244 citations

CRP-mediated activation of complement in vivo: assessment by measuring circulating complement-C-reactive protein complexes.

1996 • 233 citations

Consumption of classical complement components by heart subcellular membranes in vitro and in patients after acute myocardial infarction.

1975 • 204 citations

Association of Variables of Coagulation, Fibrinolysis and Acute-phase with Atherosclerosis in Coronary and Peripheral Arteries and those Arteries Supplying the Brain

1995 • 201 citations

Cardioprotective Effects of a C1 Esterase Inhibitor in Myocardial Ischemia and Reperfusion

1995 • 201 citations

A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells

1997 • 186 citations

Interleukin-6 is the Major Regulator of Acute Phase Protein Synthesis in Rat and Man

1989 • 182 citations

Possible Role of Cytomegalovirus in Atherogenesis

1990 • 177 citations

Plasma Protein Acute-Phase Response in Unstable Angina Is Not Induced by Ischemic Injury

1996 • 171 citations

Flip-flop: The transmembrane translocation of lipids

1994 • 144 citations

Immune and inflammatory mechanisms in the development of atherosclerosis

1993 • 139 citations

Interaction of C-reactive protein with artificial phosphatidylcholine bilayers and complement.

1981 • 133 citations

Interindividual and Intraindividual Variability in Plasma Fibrinogen, TPA Antigen, PAI Activity, and CRP in Healthy, Young Volunteers and Patients With Angina Pectoris

1996 • 130 citations

Interleukin‐6

1989 • 127 citations

The complement system in myocardial ischaemia/reperfusion injury

1994 • 126 citations

STUDIES OF ACUTE-PHASE PROTEIN. II. LOCALIZATION OF Cx-REACTIVE PROTEIN IN HEART IN INDUCED MYOCARDIAL INFARCTION IN RABBITS*

1963 • 118 citations

Cardiac dysfunction caused by purified human C3a anaphylatoxin.

1985 • 108 citations

Serum C-reactive protein and infarct size in myocardial infarct patients with a closed versus an open infarct-related coronary artery after thrombolytic therapy

1993 • 106 citations

Effects of complement activation in the isolated heart. Role of the terminal complement components.

1992 • 102 citations

IFN beta 2/BSF2/IL-6 is the monocyte-derived HSF that regulates receptor-specific acute phase gene regulation in hepatocytes.

1989 • 101 citations

IFNβ2/BSF2/IL‐6 Is the Monocyte‐derived HSF That Regulates Receptor‐specific Acute Phase Gene Regulation in Hepatocytes^a

1989 • 94 citations

The complement system in atherosclerosis

1988 • 93 citations

Early accumulation of the terminal complement-complex in the ischaemic myocardium after reperfusion

1994 • 91 citations

Localization of C‐reactive protein in synovium of patients with rheumatoid arthritis

1977 • 85 citations

Rabbits with elevated serum C-reactive protein exhibit diminished neutrophil infiltration and vascular permeability in C5a-induced alveolitis.

1993 • 79 citations

C-reactive protein as a predictor of cardiac rupture after acute myocardial infarction

1996 • 77 citations

Immunohistochemical localization of C‐reactive protein‐binding sites in human atherosclerotic aortic lesions by a modified streptavidin‐biotin‐staining method

1995 • 73 citations

Circulating human C-reactive protein binds very low density lipoproteins.

1984 • 69 citations

Quantitative measurement of SC5b-9 and C5b-9(m) in infarcted areas of human myocardium

1990 • 65 citations

Consecutive enzyme cascades: complement activation at the cell surface triggers increased tissue factor activity

1990 • 64 citations

Intravenous streptokinase treatment and serum C-reactive protein in patients with acute myocardial infarction.

1987 • 53 citations

Acute Phase Reaction, Infarct Size and In-Hospital Morbidity in Myocardial Infarction Patients Treated With Streptokinase or Recombinant Tissue Type Plasminogen Activator

1991 • 45 citations

Serum Amyloid a Protein in Patients with Acute Myocardial Infarction

1995 • 42 citations

Ischemia And Reperfusion Induced Alterations In Membrane Phospholipids: An Overview a

1994 • 40 citations

Episodic activation off the coagulation system in unstable angina does not elicit an acute phase reaction

1996 • 34 citations

PLASMA PHOSPHOLIPASE A₂ ACTIVITY IN CLINICAL ACUTE MYOCARDIAL INFARCTION

1992 • 15 citations

Acute phase response after myocardial infarction: Correlation between serum levels of cytokines and C-reactive protein

1990 • 13 citations

Involvements of fibronectin and lysophosphatidylcholine for selective binding of C-reactive protein.

1991 • 9 citations

Structure and Function of Humanc-Reactive Protein

2020 • 7 citations

Analysis of activation markers of coagulation, fibrinolysis and inflammation in unstable angina by probit transformation

1996 • 1 citations

Deleted Work

1955 • 0 citations