Molecular Regulation of Phospholamban Function and Gene Expression^a

Prediction of Protein Secondary Structure at Better than 70% Accuracy

1993 • 2,958 citations

Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence

1985 • 1,126 citations

Energy Interconversion by the Ca2+-Dependent ATPase of the Sarcoplasmic Reticulum

1979 • 718 citations

Molecular mechanism of active calcium transport by sarcoplasmic reticulum.

1978 • 586 citations

Biochemistry And Biophysics Of Excitation-Contraction Coupling

1989 • 494 citations

The Mechanism of Ca2+ Transport by Sarco(Endo)plasmic Reticulum Ca2+-ATPases

1997 • 481 citations

Concerted regulation of cardiac sarcoplasmic reticulum calcium transport by cyclic adenosine monophosphate dependent and calcium-calmodulin-dependent phosphorylations

1979 • 454 citations

Nature and site of phospholamban regulation of the Ca2+ pump of sarcoplasmic reticulum

1989 • 449 citations

Phosphorylation of the Sarcoplasmic Reticulum and Sarcolemma

1982 • 441 citations

Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains.

1986 • 435 citations

Phosphorylation of a 22,000-dalton component of the cardiac sarcoplasmic reticulum by adenosine 3':5'-monophosphate-dependent protein kinase.

1975 • 431 citations

cDNA Cloning, functional expression, and mRNA Tissue Distribution of a Third Organellar Ca2+ Pump

1989 • 412 citations

The Stimulation of Calcium Transport in Cardiac Sarcoplasmic Reticulum by Adenosine 3′:5′-Monophosphate-dependent Protein Kinase

1974 • 398 citations

Phosphorylation of troponin I and the inotropic effect of adrenaline in the perfused rabbit heart

1976 • 388 citations

Adenosine 3′:5′-Monophosphate-dependent Protein Kinase-catalyzed Phosphorylation Reaction and Its Relationship to Calcium Transport in Cardiac Sarcoplasmic Reticulum

1974 • 382 citations

Sarcoplasmic reticulum gene expression in cardiac hypertrophy and heart failure.

1994 • 373 citations

Structural and functional properties of the evolutionarily ancient Y‐box family of nucleic acid binding proteins

1994 • 367 citations

The effect of troponin I phosphorylation on the Ca2+-binding properties of the Ca2+-regulatory site of bovine cardiac troponin.

1982 • 351 citations

Regulation of myocardial Ca2+-ATPase and phospholamban mRNA expression in response to pressure overload and thyroid hormone.

1989 • 283 citations

Phospholamban Inhibitory Function Is Activated by Depolymerization

1997 • 274 citations

Phosphorylation-induced mobility shift in phospholamban in sodium dodecyl sulfate-polyacrylamide gels. Evidence for a protein structure consisting of multiple identical phosphorylatable subunits.

1984 • 254 citations

A Leucine Zipper Stabilizes the Pentameric Membrane Domain of Phospholamban and Forms a Coiled-coil Pore Structure

1996 • 252 citations

In Vivo Echocardiographic Detection of Enhanced Left Ventricular Function in Gene-Targeted Mice With Phospholamban Deficiency

1995 • 241 citations

Three-dimensional cryo-electron microscopy of the calcium ion pump in the sarcoplasmic reticulum membrane

1993 • 231 citations

Regulation of sarcoplasmic reticulum gene expression during cardiac and skeletal muscle development

1992 • 216 citations

Complete complementary DNA-derived amino acid sequence of canine cardiac phospholamban.

1987 • 201 citations

Effects of adenosine 3':5'-monophosphate-dependent protein kinase on sarcoplasmic reticulum isolated from cardiac and slow and fast contracting skeletal muscles.

1976 • 189 citations

Mutation and Phosphorylation Change the Oligomeric Structure of Phospholamban in Lipid Bilayers

1997 • 186 citations

Molecular mechanism of regulation of Ca2+ pump ATPase by phospholamban in cardiac sarcoplasmic reticulum. Effects of synthetic phospholamban peptides on Ca2+ pump ATPase.

1992 • 184 citations

Mechanism of the stimulation of Ca2+-dependent ATPase of cardiac sarcoplasmic reticulum by adenosine 3‘:5‘-monophosphate-dependent protein kinase. Role of the 22,000-dalton protein.

1979 • 175 citations

Amino acids Glu2 to Ile18 in the cytoplasmic domain of phospholamban are essential for functional association with the Ca(2+)-ATPase of sarcoplasmic reticulum.

1994 • 166 citations

Functional Co-expression of the Canine Cardiac Ca2+Pump and Phospholamban in Spodoptera frugiperda (Sf21) Cells Reveals New Insights on ATPase Regulation

1997 • 162 citations

Comparative studies of cardiac and skeletal sarcoplasmic reticulum ATPases. Effect of a phospholamban antibody on enzyme activation by Ca2+

1993 • 161 citations

Functional reconstitution of the cardiac sarcoplasmic reticulum Ca2(+)-ATPase with phospholamban in phospholipid vesicles.

1990 • 160 citations

Identification of regions in the Ca(2+)-ATPase of sarcoplasmic reticulum that affect functional association with phospholamban.

1993 • 145 citations

Mechanism by which cyclic adenosine 3':5'-monophosphate-dependent protein kinase stimulates calcium transport in cardiac sarcoplasmic reticulum.

1979 • 145 citations

Stimulation of bovine cardiac sarcoplasmic reticulum Ca2+ pump and blocking of phospholamban phosphorylation and dephosphorylation by a phospholamban monoclonal antibody.

1986 • 144 citations

Phospholamban Regulates the Ca2+-ATPase through Intramembrane Interactions

1996 • 139 citations

Purification and characterization of phospholamban from canine cardiac sarcoplasmic reticulum.

1985 • 138 citations

Amino acids Lys-Asp-Asp-Lys-Pro-Val402 in the Ca(2+)-ATPase of cardiac sarcoplasmic reticulum are critical for functional association with phospholamban.

1994 • 132 citations

Expression and Site-specific Mutagenesis of Phospholamban

1989 • 123 citations

Phospholamban Gene Dosage Effects in the Mammalian Heart

1996 • 118 citations

Calcium transport by cardiac sarcoplasmic reticulum and phosphorylation of phospholamban

1982 • 113 citations

Transient state kinetic studies of Ca2+-dependent ATPase and calcium transport by cardiac sarcoplasmic reticulum. Effect of cyclic AMP-dependent protein kinase-catalyzed phosphorylation of phospholamban.

1980 • 110 citations

Control of calcium transport in the myocardium by the cyclic AMP-Protein kinase system.

1975 • 102 citations

Functional Reconstitution of Recombinant Phospholamban with Rabbit Skeletal Ca2+-ATPase

1995 • 95 citations

Phospholamban mediates the beta-adrenergic-enhanced Ca2+ uptake in mammalian ventricular myocytes

1991 • 90 citations

Phospholamban regulation of cardiac sarcoplasmic reticulum (Ca(2+)-Mg2+)-ATPase. Mechanism of regulation and site of monoclonal antibody interaction

1991 • 86 citations

Slow/cardiac sarcoplasmic reticulum Ca²⁺‐ATPase and phospholamban mRNAs are expressed in chronically stimulated rabbit fast‐twitch muscle

1989 • 85 citations

Rabbit cardiac and slow‐twitch muscle express the same phospholamban gene

1988 • 81 citations

Structure of the rabbit phospholamban gene, cloning of the human cDNA, and assignment of the gene to human chromosome 6

1991 • 80 citations

Thyroid Hormone Enhances Ca2+ Pumping Activity of the Cardiac Sarcoplasmic Reticulum by Increasing Ca2+ ATPase and Decreasing Phospholamban Expression

1994 • 78 citations

[11] Regulation of Ca2+-pump from cardiac sarcoplasmic reticulum

1988 • 77 citations

Solution structure of the cytoplasmic domain of phospholamban: phosphorylation leads to a local perturbation in secondary structure

1995 • 73 citations

EFI_A/YB-1 Is a Component of Cardiac HF-1A Binding Activity and Positively Regulates Transcription of the Myosin Light-Chain 2v Gene

1995 • 70 citations

Secondary structure of detergent-solubilized phospholamban, a phosphorylatable, oligomeric protein of cardiac sarcoplasmic reticulum

1989 • 69 citations

Regulation of the Ca²⁺ pump atpase by cAMP‐dependent phosphorylation of phospholamban

1989 • 68 citations

Characterization of structural unit of phospholamban by amino acid sequencing and electrophoretic analysis

1986 • 61 citations

Purification and characterization of phospholamban from canine cardiac sarcoplasmic reticulum.

1985 • 57 citations

Co‐expression of slow‐twitch/cardiac muscle Ca²⁺‐ATPase (SERCA2) and phospholamban

1990 • 52 citations

Molecular Mechanism of Regulation of Ca2+ Pump ATPase by Phospholamban in Cardiac Sarcoplasmic Reticulum

1992 • 51 citations

Residues 2-25 of phospholamban are insufficient to inhibit Ca2+ transport ATPase of cardiac sarcoplasmic reticulum

1993 • 49 citations

The hydrophilic domain of phospholamban inhibits the Ca2+ transport step of the Ca2+-ATPase

1994 • 46 citations

Regulation of the calcium ion pump of sarcoplasmic reticulum: Reversible inhibition by phospholamban and by the calmodulin binding domain of the plasma membrane calcium pump

1992 • 45 citations

Molecular Structure and Function of Phospholamban in Regulating the Calcium Pump from Sarcoplasmic Reticulum

1992 • 42 citations

cDNA cloning and sequencing of phospholamban from pig stomach smooth muscle

1989 • 39 citations

Effects of monoclonal antibody against phospholamban on calcium pump ATPase of cardiac sarcoplasmic reticulum

1991 • 39 citations

Characterization of cDNA and genomic sequences encoding a chicken phospholamban.

1991 • 37 citations

Evidence for a phosphorylation‐induced conformational change in phospholamban cytoplasmic domain by CD analysis

1992 • 33 citations

Molecular Weight Determination of Phospholamban Oligomer in the Presence of Sodium Dodecyl Sulfate: Application of Low-Angle Laser Light Scattering Photometry1

1991 • 24 citations

Ellipticity changes of the sarcoplasmic reticulum Ca²⁺‐ATPase induced by cation binding and phosphorylation

1992 • 21 citations