Searching For the Function of Tissue Transglutaminase: Its Possible Involvement in the Biochemical Pathway of Programmed Cell Death

Cell Death: The Significance of Apoptosis

1980 • 7,281 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Purification and properties

1975 • 1,733 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Transglutaminases

1980 • 818 citations

The ɛ-(γ-Glutamyl)Lysine Crosslink and the Catalytic Role of Transglutaminases

1977 • 813 citations

Presence in human epidermal cells of a soluble protein precursor of the cross-linked envelope: Activation of the cross-linking by calcium ions

1979 • 792 citations

Transglutaminases

1984 • 589 citations

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 • 535 citations

Keratinocyte-specific transglutaminase of cultured human epidermal cells: Relation to cross-linked envelope formation and terminal differentiation

1985 • 479 citations

Controlled death (apoptosis) of normal and putative preneoplastic cells in rat liver following withdrawal of tumor promoters

1984 • 369 citations

On the Solubility of Fibrin Clots

1948 • 331 citations

Cross-linking of fibronectin to collagen by blood coagulation Factor XIIIa.

1979 • 325 citations

Polyamines as physiological substrates for transglutaminases.

1980 • 310 citations

The ubiquitin system: functions and mechanisms

1985 • 298 citations

Significance of Cross-Linking of α2-Plasmin Inhibitor to Fibrin in Inhibition of Fibrinolysis and in Hemostasis

1982 • 287 citations

The keratinocyte as differentiated cell type.

1980 • 260 citations

Participation of membrane-associated proteins in the formation of the cross-linked envelope of the keratinocyte

1984 • 257 citations

Enzymatic cross-linking of involucrin and other proteins by keratinocyte particulates in vitro

1985 • 235 citations

THE BIOLOGY OF CELL DEATH IN TUMOURS

1973 • 222 citations

Hormone-induced cell death. 2. Surface changes in thymocytes undergoing apoptosis.

1984 • 207 citations

Molecular and Catalytic Properties of Transglutaminases

1973 • 201 citations

Human factor XIII: fibrin-stabilizing factor.

1980 • 199 citations

Amino acid sequence of the a subunit of human factor XIII

1986 • 192 citations

Role of the intrinsic transglutaminase in the Ca2+-mediated crosslinking of erythrocyte proteins.

1976 • 187 citations

Relation of protein synthesis and transglutaminase activity to formation of the cross-linked envelope during terminal differentiation of the cultured human epidermal keratinocyte

1978 • 186 citations

Retinoic acid-induced transglutaminase in mouse epidermal cells is distinct from epidermal transglutaminase.

1985 • 183 citations

Occurrence of cell death (apoptosis) during the involution of liver hyperplasia.

1985 • 174 citations

Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells.

1985 • 161 citations

Primary structure of blood coagulation factor XIIIa (fibrinoligase, transglutaminase) from human placenta.

1986 • 158 citations

Identification of intracellular factor XIII in human monocytes and macrophages.

1985 • 154 citations

Quantitative histological and histochemical studies on the occurrence and stages of controlled cell death (apoptosis) during regression of rat liver hyperplasia

1986 • 144 citations

Human epidermal transglutaminase. Preparation and properties.

1976 • 138 citations

An enzymically catalyzed incorporation of amines into proteins

1957 • 136 citations

Characterization of cDNA coding for human factor XIIIa.

1986 • 126 citations

Identification of a substrate site for liver transglutaminase on the aminopropeptide of type III collagen.

1987 • 109 citations

Transglutaminase from Hair Follicle of Guinea Pig

1972 • 103 citations

Increase in proliferative markers after inhibition of transglutaminase.

1981 • 100 citations

Retinoic acid-induced expression of tissue transglutaminase in mouse peritoneal macrophages.

1984 • 90 citations

Covalent crosslinking of von Willebrand factor to fibrin

1986 • 85 citations

Enhanced transglutaminase activity associated with macrophage activation

1982 • 78 citations

A role for transglutaminase in glucose-stimulated insulin release from the pancreatic β-cell

1986 • 74 citations

Induction of keratinocyte type-I transglutaminase in epithelial cells of the rat

1986 • 72 citations

Transglutaminase as a marker for subsets of murine macrophages

1981 • 71 citations

Transglutaminase activity in human lymphocytes: early activation by phytomitogens.

1978 • 71 citations

Transglutaminase and neuronal differentiation

1986 • 67 citations

Transglutaminases in mammalian reproductive tissues and fluids: relation to polyamine metabolism and semen coagulation

1980 • 67 citations

Cellular transglutaminase. The particulate-associated transglutaminase from chondrosarcoma and liver: partial purification and characterization.

1986 • 65 citations

Covalent crosslinking of von Willebrand factor to fibrin

1986 • 64 citations

Catalytic properties of a calmodulin-regulated transglutaminase from human platelet and chicken gizzard.

1985 • 63 citations

Factor V is a substrate for the transamidase factor XIIIa.

1986 • 62 citations

Identification of histiocytic reticulum cells by the immunohistochemical demonstration of factor XIII (F‐XIIIa) in human lymph nodes

1986 • 61 citations

Transglutaminase-sensitive glutamine residues of human plasma fibronectin reveled by studying its proteolytic fragments

1986 • 61 citations

Transglutaminase activity during the differentiation of macrophages

1982 • 60 citations

Presence of di- and polyamines covalently bound to protein in rat liver

1985 • 59 citations

Human Epidermal Transglutaminase

1983 • 53 citations

Galactosamine-induced cell death in primary cultures of rat hepatocytes.

1980 • 52 citations

Activation of transglutaminase and production of protein-bound gamma-glutamylhistamine in stimulated mouse mast cells.

1985 • 52 citations

Human α2macroglobulin

1984 • 49 citations

Transglutaminase activity in pancreatic islets

1983 • 49 citations

Thrombospondin is a substrate for blood coagulation factor XIIIa

1986 • 48 citations

Subcellular localization of a membrane-associated transglutaminase activity in rat liver

1985 • 48 citations

Calcium‐Dependent Transglutaminase of Rat Sympathetic Ganglion in Development and After Nerve Injury

1985 • 48 citations

Haemostasis and cancer.

1989 • 46 citations

Immune-complex-induced transglut aminase activation: Its role in the Fc-receptor-mediated transmembrane effect on peritoneal macrophages

1981 • 44 citations

Ornithine decarboxylase, transglutaminase, diamine oxidase and total diamines and polyamines in maternal liver and kidney throughout rat pregnancy

1986 • 43 citations

Advances in Enzymology and Related Areas of Molecular Biology

1983 • 42 citations

Studies on the effects of dansylcadaverine and related compounds on receptor-mediated endocytosis in cultured cells.

1984 • 40 citations

Inhibition of blood coagulation factor XIII_a‐mediated cross‐linking between fibronectin and collagen by polyamines

1979 • 37 citations

Characterization of thrombospondin as a substrate for factor XIII transglutaminase.

1987 • 37 citations

Quantitation of tissue transglutaminase by a sandwich ELISA system

1986 • 35 citations

Activation of transglutaminase at calcium levels consistent with a role for this enzyme as a calcium receptor protein

1985 • 34 citations

Cellular transglutaminase. Lung matrix-associated transglutaminase: characterization and activation with sulfhydryls.

1986 • 33 citations

High-Molecular-Weight Human Epidermal Transglutaminase

1985 • 33 citations

[Destabilase: an enzyme of medicinal leech salivary gland secretion hydrolyzes the isopeptide bonds in stabilized fibrin].

1985 • 32 citations

Interferon-gamma requires serum retinoids to promote the expression of tissue transglutaminase in cultured human blood monocytes.

1985 • 32 citations

The Harvey Lectures. Series 82:1986-87

1989 • 31 citations

Rat hair follicle and epidermal transglutaminases

1981 • 31 citations

Transglutaminase activity in normal and hereditary cataractous rat lens and its partial purification

1981 • 30 citations

Human beta 2-microglobulin is a substrate of tissue transglutaminase: polymerization in solution and on the cell surface.

1981 • 29 citations

Junctions between interstitial cells of the renal medulla: A freeze-fracture study

1979 • 27 citations

Human α2 macroglobulin

1984 • 24 citations

Maturation of human promyelocytic leukemia cells induced by nicotinamide: Evidence of a regulatory role for ADP‐ribosylation of chromosomal proteins

1984 • 22 citations

MULTIPLE MOLECULAR FORMS OF TRANSGLUTAMINASES IN HUMAN AND GUINEA PIG

1975 • 19 citations

The influence of tissue transglutaminase on the function of Fc receptors

1982 • 19 citations

Rat gastrointestinal transglutaminase: Demonstration of enzyme activity and cell and tissue distributions

1985 • 19 citations

A covalently cross‐linked matrix in skeletal muscle fibers

1983 • 18 citations

Synergism and antagonism in the effects of 1 alpha,25-dihydroxyvitamin D3, retinoic acid, dexamethasone, and a tumor-promoting phorbol ester on the functional capability of P388D1 cells: phagocytosis and transglutaminase activity.

1985 • 18 citations

Transglutaminase and receptor signaling: Concepts and realities

1984 • 17 citations

The comparative ability of plasma and tissue transglutaminases to use collagen as a substrate

1980 • 17 citations

Variable transglutaminase activity in human diploid fibroblasts during in vitro senescence

1985 • 16 citations

Primary amines inhibit the triggering of B lymphocytes to antibody synthesis.

1983 • 16 citations

Dimethyl Sulfoxide-Induced Transglutaminase Activity in Murine-Derived Friend Erythroleukemia Cells

1983 • 10 citations

Activation and de novo synthesis of transglutaminase in cultured glioma cells

1985 • 10 citations

Characterization of transglutaminases in normal and malignant human leukocytes

1985 • 8 citations

Haemostasis and cancer.

1988 • 4 citations

Deleted Work

1955 • 0 citations