Calmodulin Antagonists Inhibit T-Type Ca2+ Currents in Mouse Spermatogenic Cells and the Zona Pellucida-Induced Sperm Acrosome Reaction

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Ionic Channels of Excitable Membranes

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Sequence motifs for calmodulin recognition

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Calmodulin supports both inactivation and facilitation of L-type calcium channels

1999 • 868 citations

Calmodulin Is the Ca2+ Sensor for Ca2+-Dependent Inactivation of L-Type Calcium Channels

1999 • 822 citations

Mammalian Fertilization

1999 • 751 citations

Dynamics of the mammalian sperm plasma membrane in the process of fertilization

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Physiological implications of the presence, distribution, and regulation of calmodulin in eukaryotic cells.

1982 • 516 citations

The Ca2+–calmodulin-dependent protein kinase cascade

1999 • 502 citations

Ca2+/calmodulin binds to and modulates P/Q-type calcium channels

1999 • 478 citations

Voltage-dependent calcium channels: From structure to function

2005 • 341 citations

Ion Channels in Sperm Physiology

1999 • 329 citations

Cholesterol Efflux-mediated Signal Transduction in Mammalian Sperm

1999 • 318 citations

Cloning and functional expression of a cyclic-nucleotide-gated channel from mammalian sperm

1994 • 312 citations

Ca²⁺-induced inhibition of the cardiac Ca²⁺channel depends on calmodulin

1999 • 276 citations

Methods for Evaluating the Acrosomal Status of Mammalian Sperm1

1989 • 230 citations

Activation of mouse sperm T-type Ca ²⁺ channels by adhesion to the egg zona pellucida

1996 • 228 citations

Control of the low voltage-activated calcium channel of mouse sperm by egg ZP3 and by membrane hyperpolarization during capacitation

1999 • 223 citations

Ca ²⁺ -sensitive inactivation of L-type Ca ²⁺ channels depends on multiple cytoplasmic amino acid sequences of the α _1C subunit

1998 • 183 citations

T‐type Ca²⁺ channels and α_1E expression in spermatogenic cells, and their possible relevance to the sperm acrosome reaction

1996 • 164 citations

ZP3-dependent activation of sperm cation channels regulates acrosomal secretion during mammalian fertilization.

1996 • 140 citations

A dihydropyridine-sensitive T-type Ca2+ current is the main Ca2+ current carrier in mouse primary spermatocytes

1996 • 135 citations

Calmodulin localization in mammalian spermatozoa.

1980 • 123 citations

Pharmacological properties of the T-type Ca2+ current of mouse spermatogenic cells.

1998 • 119 citations

Voltage-dependent modulation of T-type calcium channels by protein tyrosine phosphorylation

1997 • 103 citations

State-Dependent Inactivation of the α1g T-Type Calcium Channel

1999 • 96 citations

Calcium and potassium currents in spermatogenic cells dissociated from rat seminiferous tubules.

1984 • 96 citations

Evidence for plasma membrane impermeability to small ions in acrosome- intact mouse spermatozoa bound to mouse zonae pellucidae, using an aminoacridine fluorescent pH probe: time course of the zona-induced acrosome reaction monitored by both chlortetracycline and pH probe fluorescence

1985 • 80 citations

Trifluoperazine binding to porcine brain calmodulin and skeletal muscle troponin C

1990 • 77 citations

Evidence for the Involvement of Calmodulin in Mouse Sperm Capacitation1

2000 • 75 citations

Mouse sperm patch‐clamp recordings reveal single Cl⁻ channels sensitive to niflumic acid, a blocker of the sperm acrosome reaction

1998 • 59 citations

Calmidazolium leads to an increase in the cytosolic Ca2+ concentration in Dictyostelium discoideum by induction of Ca2+ release from intracellular stores and influx of extracellular Ca2+

1996 • 54 citations

Paramecium calcium channels are blocked by a family of calmodulin antagonists.

1988 • 49 citations

Egg jelly triggers a calcium influx which inactivates and is inhibited by calmodulin antagonists in the sea urchin sperm

1989 • 47 citations

Inhibition of olfactory cyclic nucleotide‐activated current by calmodulin antagonists

1994 • 36 citations

Localization of Calmodulin in perinuclear structures of spermatids and spermatozoa: A comparison of six mammalian species

1991 • 35 citations

Anticalmodulin drugs block the sodium gating current of squid giant axons

1991 • 35 citations

The Actions of Calmodulin Antagonists W-7 and TFP and of Calcium on the Gating Kinetics of the Calcium-activated Large Conductance Potassium Channel of the Chara Protoplasmic Drop: A Substate-sensitive Analysis

1997 • 19 citations

Inhibition of the acrosome reaction of sea urchin spermatozoa by a calmodulin antagonist, N‐(6‐aminohexyl)‐5‐chloro‐1‐naphthalenesulfonamide (W‐7)

1983 • 17 citations

Determination of the intracellular dissociation constant, KD, of the Fluo-3 � Ca2+ complex in mouse sperm for use in estimating intracellular Ca2+ concentrations

1999 • 12 citations

Ca2+/Calmodulin Inhibition and Phospholipase C-Linked Ca2+ Signaling in Clonalβ -Cells1

1999 • 11 citations

Calmodulin binding proteins in the membrane vesicles released during the acrosome reaction and in the perinuclear material in isolated acrosome reacted sperm heads

1994 • 8 citations

Calmodulin, gametes and fertilisation

1999 • 5 citations