The proliferative and morphologic responses of a colon carcinoma cell line (LIM 1215) require the production of two autocrine factors.

Growth factors from murine sarcoma virus-transformed cells.

1978 • 1,457 citations

Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer

1985 • 1,360 citations

Scatter factor is a fibroblast-derived modulator of epithelial cell mobility

1987 • 1,333 citations

Type beta transforming growth factor: a bifunctional regulator of cellular growth.

1985 • 1,107 citations

Culture of hormone-dependent functional epithelial cells from rat thyroids.

1980 • 959 citations

Human transforming growth factor-α: Precursor structure and expression in E. coli

1984 • 888 citations

Transforming growth factor production by chemically transformed cells.

1981 • 506 citations

Transforming growth factors: isolation of polypeptides from virally and chemically transformed cells by acid/ethanol extraction.

1980 • 461 citations

A c- myb Antisense Oligodeoxynucleotide Inhibits Normal Human Hematopoiesis in Vitro

1988 • 439 citations

Purification of scatter factor, a fibroblast-derived basic protein that modulates epithelial interactions and movement.

1989 • 411 citations

Transforming growth factors produced by retrovirus-transformed rodent fibroblasts and human melanoma cells: amino acid sequence homology with epidermal growth factor.

1983 • 403 citations

Sarcoma growth factor from conditioned medium of virally transformed cells is composed of both type alpha and type beta transforming growth factors.

1983 • 381 citations

Transformation by murine and feline sarcoma viruses specifically blocks binding of epidermal growth factor to cells

1976 • 374 citations

Expression of messenger RNAs for platelet-derived growth factor and transforming growth factor-alpha and their receptors in human malignant glioma cell lines.

1988 • 354 citations

Hierarchical down-modulation of hemopoietic growth factor receptors

1985 • 314 citations

Transforming gene from human stomach cancers and a noncancerous portion of stomach mucosa.

1986 • 277 citations

Transforming protein of simian sarcoma virus stimulates autocrine growth of SSV-transformed cells through PDGF cell-surface receptors

1984 • 277 citations

Proliferation of human malignant melanomas is inhibited by antisense oligodeoxynucleotides targeted against basic fibroblast growth factor.

1989 • 270 citations

Different transforming growth factor-α species are derived from a glycosylated and palmitoylated transmembrane precursor

1987 • 264 citations

Synergistic interaction of two classes of transforming growth factors from murine sarcoma cells.

1982 • 263 citations

The int-2 gene product acts as an epithelial growth factor in transgenic mice.

1990 • 263 citations

Expression of a Platelet-Derived Growth Factor-Like Protein in Simian Sarcoma Virus Transformed Cells

1983 • 246 citations

Kirsten murine sarcoma virus transformed cell lines and a spontaneously transformed rat cell‐line produce transforming factors

1980 • 244 citations

Production of transforming growth factors by human colon cancer lines.

1986 • 227 citations

Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells

1985 • 226 citations

Transforming growth factor alpha and beta expression in human colon cancer lines: implications for an autocrine model.

1987 • 222 citations

Transforming growth factor(s) production enables cells to grow in the absence of serum: an autocrine system.

1982 • 219 citations

Isolation from murine sarcoma cells of novel transforming growth factors potentiated by EGF

1982 • 206 citations

Antibodies against platelet-derived growth factor inhibit acute transformation by simian sarcoma virus

1985 • 205 citations

Growth factor production by human colon carcinoma cell lines.

1989 • 186 citations

Construction of a Novel Oncogene Based on Synthetic Sequences Encoding Epidermal Growth Factor

1987 • 162 citations

A Colon Cancer Cell Line (LIM1215) Derived From a Patient With Inherited Nonpolyposis Colorectal Cancer<xref ref-type="fn" rid="FN1">2</xref>

1985 • 159 citations

Epidermal growth factor induces redistribution of actin and α-actinin in human epidermal carcinoma cells

1981 • 139 citations

Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells.

1986 • 133 citations

Expression of transforming growth factor alpha messenger rna in the normal and neoplastic gastro‐intestinal tract

1989 • 132 citations

The int genes in mammary tumorigenesis and in normal development

1988 • 117 citations

Studies on Carcinogenesis by Avian Sarcoma Viruses. III. The Differential Effect of Serum and Polyanions on Multiplication of Uninfected and Converted Cells<xref ref-type="fn" rid="FN2">2</xref>

1966 • 100 citations

Growth of normal human glial cells in a defined medium containing platelet-derived growth factor.

1980 • 73 citations

Properties of a sarcoma‐growth‐factor‐like peptide from cells transformed by a temperature‐sensitive sarcoma virus

1981 • 71 citations

A nonmitogenic analogue of epidermal growth factor induces early responses mediated by epidermal growth factor.

1982 • 64 citations

Growth control of prostatic carcinoma cells in serum-free media: interrelationship of hormone response, cell density, and nutrient media.

1981 • 53 citations

Liver epithelial cell migration induced by epidermal growth factor or transforming growth factor alpha is associated with changes in the gene expression of secreted proteins

1988 • 49 citations

Purification and characterization of a novel transforming growth factor.

1987 • 39 citations

Extracellular matrix (ECM) modulates the EGF-induced migration of liver epithelial cells in serum-free, hormone-supplemented medium

1985 • 27 citations

The Action of Epidermal Growth Factor (EGF) is Limited to Specific Phases of the Cell Cycle in an EGF Dependent Colonic Cell Line

1991 • 16 citations

An Autocrine Activity Capable of Substituting for Serum in Cell Cultures

1989 • 8 citations