beta-cell glucotoxicity in the Psammomys obesus model of type 2 diabetes.

Spontaneous long-term hyperglycemic rat with diabetic complications. Otsuka Long-Evans Tokushima Fatty (OLETF) strain

1992 • 869 citations

Hyperglycemia-induced beta-cell apoptosis in pancreatic islets of Psammomys obesus during development of diabetes.

1999 • 401 citations

Zucker Diabetic Fatty Rat as a Model for Non-insulin-dependent Diabetes Mellitus

1990 • 318 citations

Glucose modulates the binding of an islet-specific factor to a conserved sequence within the rat I and the human insulin promoters.

1993 • 177 citations

Characterization of Stages in Development of Obesity-Diabetes Syndrome in Sand Rat (Psammomys obesus)

1986 • 90 citations

Monolayer Culture of Adult Rat Pancreatic Islets on Extracellular Matrix: Modulation of B-Cell Function by Chronic Exposure to High Glucose*

1991 • 77 citations

PSAMMOMYS OBESUS OF THE JERUSALEM COLONY: A MODEL FOR NUTRITIONALLY INDUCED, NON-INSULIN-DEPENDENT DIABETES

1993 • 66 citations

THE EFFICIENCY OF SAND RAT METABOLISM IS RESPONSIBLE FOR DEVELOPMENT OF OBESITY AND DIABETES

1993 • 60 citations

Monolayer Culture of Adult Rat Pancreatic Islets on Extracellular Matrix: Long Term Maintenance of Differentiated B-Cell Function*

1988 • 52 citations

Hyperproinsulinemia and insulin deficiency in the diabetic Psammomys obesus.

1994 • 47 citations

Interaction between genetic and dietary factors determines beta-cell function in Psammomys obesus, an animal model of type 2 diabetes.

1999 • 45 citations

Increased susceptibility of islets from diabetes-prone Psammomys obesus to the deleterious effects of chronic glucose exposure.

1996 • 33 citations

Hyperproinsulinemia in the diabetic Psammomys obesus is a result of increased secretory demand on the beta-cell.

1995 • 33 citations

The sand rat (Psammomys obesus): morphologic, physiologic, and biochemical characteristics of a model for type-II diabetes mellitus.

1996 • 11 citations

Characterization of the Unusual Insulin of Psammomys obesus, a Rodent With Nutrition-Induced NIDDM-Like Syndrome

1997 • 5 citations