Effects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA

Natural selection shaped regional mtDNA variation in humans

2002 • 1,019 citations

Uncoupling to survive? The role of mitochondrial inefficiency in ageing

2000 • 745 citations

Late Pleistocene human population bottlenecks, volcanic winter, and differentiation of modern humans

1998 • 649 citations

Mitochondrial Polymorphisms Significantly Reduce the Risk of Parkinson Disease

2003 • 543 citations

Human mtDNA Haplogroups Associated with High or Reduced Spermatozoa Motility

2000 • 501 citations

Mitochondrial DNA variation in human evolution and disease

1999 • 462 citations

Mitochondrial DNA inherited variants are associated with successful aging and longevity in humans

1999 • 385 citations

Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns

1983 • 316 citations

Mitochondrial DNA polymorphisms associated with longevity in a Finnish population

2003 • 245 citations

Clustering of Caucasian Leber hereditary optic neuropathy patients containing the 11778 or 14484 mutations on an mtDNA lineage.

1997 • 219 citations

The role of mtDNA background in disease expression: a new primary LHON mutation associated with Western Eurasian haplogroup J

2002 • 213 citations

Mitochondrial DNA polymorphism: its role in longevity of the Irish population

2001 • 178 citations

Molecular basis for resistance to antimycin and diuron, Q-cycle inhibitors acting at the Qi site in the mitochondrial ubiquinol-cytochrome c reductase in Saccharomyces cerevisiae.

1988 • 175 citations

Climatic influences on basal metabolic rates among circumpolar populations

2002 • 174 citations

Mitochondrial DNA haplogroups and APOE4 allele are non-independent variables in sporadic Alzheimer's disease

2001 • 170 citations

A motif for quinone binding sites in respiratory and photosynthetic systems 1 1Edited by R. Huber

2000 • 160 citations

Contingency Tests of Neutrality Using Intra/Interspecific Gene Trees: The Rejection of Neutrality for the Evolution of the Mitochondrial Cytochrome Oxidase II Gene in the Hominoid Primates

1996 • 127 citations

Phylogenetic analysis of the mitochondrial genome indicates significant differences between patients with Alzheimer disease and controls in a French-Canadian founder population

1999 • 126 citations

The Crystal Structure of Mitochondrial Cytochrome bc1 in Complex with Famoxadone: The Role of Aromatic−Aromatic Interaction in Inhibition^,

2002 • 125 citations

Wolfram (DIDMOAD) Syndrome and Leber Hereditary Optic Neuropathy (LHON) Are Associated with Distinct Mitochondrial DNA Haplotypes

1997 • 91 citations

Effects of mutations in mitochondrial cytochrome b in yeast and man

2001 • 56 citations

Characterization of the mitochondrial DNA in patients with multiple sclerosis

1996 • 46 citations

An allele of HRAS1 3′variable number of tandem repeats is a frailty allele: implication for an evolutionarily-conserved pathway involved in longevity

2002 • 37 citations

Aspartate-187 of Cytochrome b Is Not Needed for DCCD Inhibition of Ubiquinol: Cytochrome c Oxidoreductase in Rhodobacter sphaeroides Chromatophores

2000 • 7 citations