Antiproliferative effect of dehydrodidemnin B (DDB), a depsipeptide isolated from Mediterranean tunicates

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

1989 • 3,477 citations

Ornithine decarboxylase activity is critical for cell transformation

1992 • 630 citations

Molecular genetics of polyamine synthesis in eukaryotic cells

1990 • 519 citations

Didemnins: Antiviral and Antitumor Depsipeptides from a Caribbean Tunicate

1981 • 308 citations

GTP-dependent binding of the antiproliferative agent didemnin to elongation factor 1 alpha.

1994 • 136 citations

Nitrogen movement between host and tumor in mice inoculated with Ehrlich ascitic tumor cells.

1984 • 90 citations

Biochemical and cellular effects of didemnins A and B.

1984 • 74 citations

Crystal and molecular structure of didemnin B, an antiviral and cytotoxic depsipeptide.

1988 • 71 citations

Prolactin-dependent mitogenesis in Nb 2 node lymphoma cells: effects of immunosuppressive cyclopeptides.

1987 • 66 citations

Phase I clinical and pharmacokinetic investigation of didemnin B, a cyclic depsipeptide

1988 • 66 citations

Mechanism of action of didemnin B, a depsipeptide from the sea

1984 • 63 citations

Decreased protein-synthetic activity is an early consequence of spermidine depletion in rat hepatoma tissue-culture cells

1984 • 57 citations

Antiviral and antitumor compounds from tunicates.

1983 • 45 citations

Phase II clinical trial of didemnin B in previously treated small cell lung cancer

1994 • 40 citations

Antineoplastic activity of didemnin congeners: nordidemnin and modified chain analogs

1991 • 39 citations

Mammalian l-amino acid decarboxylases producing 1,4-diamines: analogies among differences

1994 • 37 citations

Chlorpheniramine inhibits the ornithine decarboxylase induction of Ehrlich carcinoma growing in vivo

1992 • 30 citations

A phase II trial of didemnin B in myeloma

1994 • 26 citations

Didemnin B inhibits biological effects of tumor promoting phorbol esters on mouse skin, as well as phosphorylation of a 100 kD protein in mouse epidermis cytosol

1987 • 25 citations

Alterations in mRNA translation as a mechanism for the modification of enzyme synthesis during evolution. The ornithine decarboxylase model.

1992 • 22 citations

Didemnin B in metastatic malignant melanoma: a phase II trial of the Southwest Oncology Group.

1994 • 21 citations

Chlorpheniramine inhibits the synthesis of ornithine decarboxylase and the proliferation of human breast cancer cell lines

1995 • 21 citations

Didemnin B in metastatic malignant melanoma

1994 • 20 citations

Ornithine decarboxylase-induced cellular transformation: the involvement of protein tyrosine kinase(s) and pp130

1994 • 10 citations

Expression of different mitogen‐regulated protein/proliferin mRNAs in Ehrlich carcinoma cells

1994 • 9 citations

Immunomodulation by Didemnins

1994 • 8 citations

Inhibition of immediate-early-gene induction in renal mesangial cells by depletion of intracellular polyamines

1994 • 7 citations

The induction of ornithine decarboxylase by ornithine takes place at post-transcriptional level in perifused Ehrlich carcinoma cells

1992 • 5 citations

Vinca alkaloids enhance the half-life of tumour ornithine decarboxylase

1994 • 4 citations