Magnetic Resonance Studies of Brain Function and Neurochemistry

Receptive fields, binocular interaction and functional architecture in the cat's visual cortex

1962 • 13,401 citations

Functional connectivity in the motor cortex of resting human brain using echo‐planar mri

1995 • 9,444 citations

Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient

1965 • 7,940 citations

Brain magnetic resonance imaging with contrast dependent on blood oxygenation.

1990 • 6,189 citations

Resonance Absorption by Nuclear Magnetic Moments in a Solid

1946 • 5,669 citations

Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation.

1992 • 4,175 citations

Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging.

1992 • 3,618 citations

Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance

1973 • 3,442 citations

Ferrier lecture - Functional architecture of macaque monkey visual cortex

1977 • 2,599 citations

Oxygenation‐sensitive contrast in magnetic resonance image of rodent brain at high magnetic fields

1990 • 2,225 citations

Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects.

1986 • 2,017 citations

Time course EPI of human brain function during task activation

1992 • 1,893 citations

Nonoxidative Glucose Consumption During Focal Physiologic Neural Activity

1988 • 1,775 citations

Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging. A comparison of signal characteristics with a biophysical model

1993 • 1,740 citations

Retinotopic organization in human visual cortex and the spatial precision of functional MRI

1997 • 1,627 citations

Perfusion imaging

1992 • 1,497 citations

Functional architecture of cortex revealed by optical imaging of intrinsic signals

1986 • 1,246 citations

Glutamine Synthetase: Glial Localization in Brain

1977 • 1,170 citations

Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field

1982 • 1,108 citations

Interactions Between Electrical Activity and Cortical Microcirculation Revealed by Imaging Spectroscopy: Implications for Functional Brain Mapping

1996 • 1,107 citations

Quantification of relative cerebral blood flow change by flow‐sensitive alternating inversion recovery (FAIR) technique: Application to functional mapping

1995 • 1,002 citations

Mr contrast due to intravascular magnetic susceptibility perturbations

1995 • 991 citations

Cortical functional architecture and local coupling between neuronal activity and the microcirculation revealed by in vivo high-resolution optical imaging of intrinsic signals.

1990 • 967 citations

Iso-orientation domains in cat visual cortex are arranged in pinwheel-like patterns

1991 • 859 citations

Automatic, localized in Vivo adjustment of all first‐and second‐order shim coils

1993 • 851 citations

A Model for the Coupling between Cerebral Blood Flow and Oxygen Metabolism during Neural Stimulation

1997 • 784 citations

Microscopic susceptibility variation and transverse relaxation: Theory and experiment

1994 • 707 citations

Quantitative imaging of perfusion using a single subtraction (QUIPSS and QUIPSS II)

1998 • 682 citations

Ocular dominance columns and their development in layer IV of the cat's visual cortex: A quantitative study

1978 • 671 citations

Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency.

1994 • 651 citations

The intravascular contribution to fmri signal change: monte carlo modeling and diffusion‐weighted studies in vivo

1995 • 592 citations

Detection of cortical activation during averaged single trials of a cognitive task using functional magnetic resonance imaging

1996 • 587 citations

The Role of Visual Experience in the Development of Columns in Cat Visual Cortex

1998 • 583 citations

Dynamic functional imaging of relative cerebral blood volume during rat forepaw stimulation

1998 • 551 citations

Functional imaging of the monkey brain

1999 • 548 citations

Magnetic resonance imaging of blood vessels at high fields: In vivo and in vitro measurements and image simulation

1990 • 546 citations

Functional Organization of Primate Visual Cortex Revealed by High Resolution Optical Imaging

1990 • 535 citations

Intravascular susceptibility contrast mechanisms in tissues

1994 • 528 citations

Experimental determination of the BOLD field strength dependence in vessels and tissue

1997 • 527 citations

Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging

1998 • 500 citations

Retrospective estimation and correction of physiological fluctuation in functional MRI

1995 • 482 citations

Mr perfusion studies with t₁‐weighted echo planar imaging

1995 • 473 citations

Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo ¹³ C NMR

1999 • 445 citations

BOLD Based Functional MRI at 4 Tesla Includes a Capillary Bed Contribution: Echo‐Planar Imaging Correlates with Previous Optical Imaging Using Intrinsic Signals

1995 • 428 citations

The Molecular Beam Resonance Method for Measuring Nuclear Magnetic Moments. The Magnetic Moments of<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:mmultiscripts><mml:mrow><mml:mi mathvariant="normal">Li</mml:mi></mml:mrow><mml:mrow /><mml:mrow><mml:mn>6</mml:mn></mml:mrow><mml:mrow /><mml:mrow /><mml:mprescripts /><mml:mrow><mml:mn>3</mml:mn></mml:mrow><mml:mrow /><mml:mrow /><mml:mrow /></mml:mmultiscripts></mml:mrow></mml:math>,<mml:math xmlns:mml="…

1939 • 401 citations

High-resolution mapping of iso-orientation columns by fMRI

2000 • 392 citations

Dynamic mapping of the human visual cortex by high-speed magnetic resonance imaging.

1992 • 371 citations

ON THE CHARACTERISTICS OF FUNCTIONAL MAGNETIC RESONANCE IMAGING OF THE BRAIN

1998 • 341 citations

Clearance of glutamate inside the synapse and beyond

1999 • 329 citations

Tissue specific perfusion imaging using arterial spin labeling

1994 • 328 citations

Increased Cortical Oxidative Metabolism Due to Sensory Stimulation: Implications for Functional Brain Imaging

1999 • 326 citations

Dynamic uncoupling and recoupling of perfusion and oxidative metabolism during focal brain activation in man

1996 • 320 citations

In vivo ¹³ C NMR measurements of cerebral glutamine synthesis as evidence for glutamate–glutamine cycling

1997 • 315 citations

Quantitative capillary topography and blood flow in the cerebral cortex of cats: an in vivo microscopic study

1981 • 313 citations

Reduction of physiological fluctuations in fMRI using digital filters

1996 • 307 citations

Metabolic mapping of the primary visual system of the monkey by means of the autoradiographic [14C]deoxyglucose technique.

1976 • 306 citations

Ocular Dominance in Human V1 Demonstrated by Functional Magnetic Resonance Imaging

1997 • 296 citations

Evidence of the Limitations of Water as a Freely Diffusible Tracer in Brain of the Rhesus Monkey

1974 • 277 citations

Limitations of temporal resolution in functional MRI

1997 • 275 citations

High-resolution optical imaging of functional brain architecture in the awake monkey.

1991 • 274 citations

The complete pattern of ocular dominance stripes in the striate cortex and visual field of the macaque monkey

1985 • 273 citations

Evaluation of the early response in fMRI in individual subjects using short stimulus duration

1997 • 261 citations

Mental chronometry using latency-resolved functional MRI

1998 • 260 citations

Reduction of signal fluctuation in functional MRI using navigator echoes

1994 • 251 citations

Functional Organization for Direction of Motion and Its Relationship to Orientation Maps in Cat Area 18

1996 • 248 citations

Mapping of cytochrome oxidase patches and ocular dominance columns in human visual cortex

1984 • 248 citations

Perfusion imaging by a flow‐sensitive alternating inversion recovery (Fair) technique: Application to functional brain imaging

1997 • 246 citations

Observation of a fast response in functional MR

1994 • 243 citations

Localized ¹³C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from <scp>d</scp>‐[1‐¹³C]Glucose

1994 • 241 citations

Steady‐State Cerebral Glucose Concentrations and Transport in the Human Brain

1998 • 239 citations

Direct measurement of brain glucose concentrations in humans by 13C NMR spectroscopy.

1992 • 228 citations

Glutamate transporter currents in Bergmann glial cells follow the time course of extrasynaptic glutamate

1997 • 223 citations

Comparison of blood oxygenattion and cerebral blood flow effect in fMRI: Estimation of relative oxygen consumption change

1997 • 222 citations

Orientation Selectivity in Pinwheel Centers in Cat Striate Cortex

1997 • 210 citations

Spatial and temporal limits in cognitive neuroimaging with fMRI

1999 • 210 citations

Diffusion weighted fMRI at 1.5 T

1996 • 209 citations

Localized in vivo &lt;sup&gt;13&lt;/sup&gt;C-NMR of Glutamate Metabolism in the Human Brain: Initial Results at 4 Tesla

1998 • 197 citations

Time-resolved fMRI of mental rotation

1997 • 197 citations

Resolution Improvements inin Vivo1H NMR Spectra with Increased Magnetic Field Strength

1998 • 193 citations

The nature of spatiotemporal changes in cerebral hemodynamics as manifested in functional magnetic resonance imaging

1997 • 188 citations

Increased tricarboxylic acid cycle flux in rat brain during forepaw stimulation detected with 1H[13C]NMR.

1996 • 188 citations

Quantitative magnetic resonance imaging of human brain perfusion at 1.5 T using steady-state inversion of arterial water.

1994 • 181 citations

Submillimeter functional localization in human striate cortex using BOLD contrast at 4 Tesla: Implications for the vascular point-spread function

1999 • 172 citations

Surface organization of orientation and direction selectivity in cat area 18

1987 • 169 citations

A Half-Volume Coil for Efficient Proton Decoupling in Humans at 4 Tesla

1997 • 169 citations

Hypercapnia Reversibly Suppresses Low-Frequency Fluctuations in the Human Motor Cortex during Rest Using Echo–Planar MRI

1997 • 168 citations

2D and 3D high resolution gradient echo functional imaging of the brain: Venous contributions to signal in motor cortex studies

1994 • 167 citations

Sequential activity in human motor areas during a delayed cued finger movement task studied by time-resolved fMRI

1997 • 152 citations

Functional mapping in the human brain using high magnetic fields

1999 • 151 citations

High-resolution 13C nuclear magnetic resonance studies of glucose metabolism in Escherichia coli.

1978 • 141 citations

Filtration and diffusion of water across the blood-brain barrier in man

1977 • 133 citations

Topographic organization of the orientation column system in large flat‐mounts of the cat visual cortex: A 2‐deoxyglucose study

1987 • 128 citations

Mechanisms of Contrast in NMR Imaging

1984 • 127 citations

Arrangement of Ocular Dominance Columns in Human Visual Cortex

1990 • 126 citations

Oxidative Glucose Metabolism in Rat Brain during Single Forepaw Stimulation: A Spatially Localized ¹H[¹³C] Nuclear Magnetic Resonance Study

1997 • 125 citations

MR relaxation times in human brain: measurement at 4 T.

1996 • 122 citations

Proton NMR relaxation times of human blood samples at 1.5 T and implications for functional MRI.

1997 • 113 citations

Reverse occlusion leads to a precise restoration of orientation preference maps in visual cortex

1994 • 104 citations

Localized in vivo ¹ H NMR detection of neurotransmitter labeling in rat brain during infusion of [1‐ ¹³ C] D‐glucose

1999 • 101 citations

A quantitative interpretation of IVIM measurements of vascular perfusion in the rat brain

1994 • 98 citations

Localized in vivo1H NMR detection of neurotransmitter labeling in rat brain during infusion of [1-13C] D-glucose

1999 • 96 citations

Perte de la palole, ramollisement chronique et destruction partielle du lobe anterieure gauche du ceveau

1861 • 90 citations

Broadband decoupled, ¹H‐localized ¹³C MRS of the human brain at 4 tesla

1996 • 74 citations

On the Nuclear Moments of Indium

1938 • 53 citations

Water filtration and diffusion across the blood brain barrier in man.

1977 • 26 citations

Limitations of temporal resolution in fMRI

1996 • 23 citations

Mapping ocular dominance columns in human V1 using fMRI

1996 • 14 citations

Food For Thought

1997 • 11 citations

Further evaluation of the initial negative response in functional magnetic resonance imaging

1999 • 6 citations

Diffusion‐weighted spin‐echo fMRI at 9.4 T: Microvascular/tissue contribution to BOLD signal changes

1999 • 3 citations