Mycobacterium leprae fails to stimulate phagocytic cell superoxide anion generation

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Isolation of mononuclear cells and granulocytes from human blood.

1968 • 9,672 citations

Oxygen-Dependent Microbial Killing by Phagocytes

1978 • 2,519 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

1984 • 362 citations

A method for counting acid-fast bacteria.

1968 • 325 citations

Failure to trigger the oxidative metabolic burst by normal macrophages: possible mechanism for survival of intracellular pathogens.

1980 • 322 citations

Structure and antigenicity of the major specific glycolipid antigen of Mycobacterium leprae.

1982 • 265 citations

Ultrastructural Study of the Behavior of Macrophages Toward Parasitic Mycobacteria

1972 • 181 citations

Killing of Mycobacterium microti by immunologically activated macrophages

1981 • 171 citations

Virulence and Resistance to Superoxide, Low pH and Hydrogen Peroxide among Strains of Mycobacterium tuberculosis

1978 • 165 citations

Dissociation of phagocytosis from stimulation of the oxidative metabolic burst in macrophages.

1984 • 160 citations

T-cell conditioned media reverse T-cell unresponsiveness in lepromatous leprosy

1983 • 140 citations

Immunological Unresponsiveness in Leprosy

1984 • 135 citations

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2.

1983 • 131 citations

SECRETION OF SUPEROXIDE ANION

1981 • 101 citations

Intracellular destruction of Leishmania tropica by macrophages activated with macrophage activating factor/interferon.

1984 • 78 citations

Failure of the phagocytic oxidative response to protect human monocyte-derived macrophages from infection by Leishmania donovani.

1982 • 77 citations

Toxic effect of the peroxidase-hydrogen peroxide-halide antimicrobial system on Mycobacterium leprae

1984 • 58 citations

Mechanism of immunosuppression in leprosy: presence of suppressor factor(s) from macrophages of lepromatous patients

1983 • 55 citations

Superoxide Dismutase, Peroxidatic Activity and Catalase in Mycobacterium leprae Purified from Armadillo Liver

1980 • 55 citations

Oxygen metabolism in phagocytes of leprotic patients: enhanced endogenous superoxide dismutase activity and hydroxyl radical generation by clofazimine

1984 • 51 citations

Deficit of interleukin 2 production associated with impaired T-cell proliferative responses in Mycobacterium lepraemurium infection

1983 • 51 citations

Resistance of various strains of mycobacteria to killing by activated macrophages in vivo.

1983 • 39 citations

Interleukin 1 production by peripheral blood mononuclear cells from leprosy patients

1984 • 37 citations

Reversal by Interleukin‐2 of the T Cell Unresponsiveness of Lepromatous Leprosy to Mycobacterium Leprae

1984 • 36 citations

Leukocyte antimicrobial function in patients with leprosy.

1974 • 31 citations

The role of macrophages in the lymphoproliferative response to Mycobacterium leprae in vitro.

1978 • 30 citations

Superoxide production in pulmonary alveolar macrophages and killing of BCG by the superoxide-generating system with or without catalase

1979 • 30 citations

Intracellular location of Mycobacterium leprae in macrophages of normal and immune-deficient mice and effect of rifampin

1983 • 29 citations

Suppression of immunity to Mycobacterium lepraemurium infection

1977 • 25 citations

Susceptibility of Mycobacterium intracellulare to Hydrogen Peroxide

1984 • 22 citations

Behavior of Mycobacterium leprae in Human Macrophages In Vitro

1973 • 21 citations

Role of macrophages in defective cell mediated immunity in lepromatous leprosy. I. Factor(s) from macrophages affecting protein synthesis and lymphocyte transformation.

1980 • 18 citations

Polymorphonuclear cell function in the various polar types of leprosy and erythema nodosum leprosum

1978 • 17 citations

LYSOSOME FUSION RESPONSES OF MACROPHAGES TO INFECTION: BEHAVIOR AND SIGNIFICANCE

1982 • 16 citations

Influence of dose and route of Mycobacterium lepraemurium inoculation on the production of interleukin 1 and interleukin 2 in C57BL/6 mice

1984 • 15 citations

Macrophage function in Mycobacterium lepraemurium infection: morphological and functional changes of peritoneal and splenic macrophages in vitro

1983 • 11 citations

Macrophages and protective immunity in Mycobacterium lepraemurium infections in a 'resistant' (C57Bl) and a 'susceptible' (BALB/c) mouse strain.

1982 • 10 citations

NBT responses of neutrophils and monocytes in leprosy.

1974 • 8 citations

Defective blood mononuclear phagocyte function in patients with leprosy.

1979 • 5 citations

Phagocytosis in leprosy. 2. Production of superoxide by circulating blood leukocytes from lepromatous patients.

1978 • 5 citations

MURINE LEPROSY AS A MODEL FOR THE ANALYSIS OF GENETIC FACTORS CONTROLLING RESISTANCE TO MYCOBACTERIAL INFECTION

1980 • 4 citations

Biochemical alteration in cells following phagocytosis of M. leprae--the consequence--a basic concept.

1980 • 4 citations

Defective leukotaxis in patients with lepromatous leprosy.

1976 • 1 citations