Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.

The interpretation of protein structures: Estimation of static accessibility

1971 • 5,771 citations

Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

1991 • 5,267 citations

AREAS, VOLUMES, PACKING, AND PROTEIN STRUCTURE

1977 • 2,631 citations

Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor

1992 • 1,887 citations

Crystal structure of human immunodeficiency virus type 1 reverse transcriptase complexed with double-stranded DNA at 3.0 A resolution shows bent DNA.

1993 • 1,097 citations

Principles of protein–protein recognition

1975 • 1,028 citations

Entropic Contributions to Rate Accelerations in Enzymic and Intramolecular Reactions and the Chelate Effect

1971 • 980 citations

Hydrophobic bonding and accessible surface area in proteins

1974 • 887 citations

Crystal Structure of the Ribonuclease H Domain of HIV-1 Reverse Transcriptase

1991 • 566 citations

Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.

1994 • 329 citations

The price of lost freedom: entropy of bimolecular complex formation

1989 • 323 citations

HIV-1 reverse transcriptase specifically interacts with the anticodon domain of its cognate primer tRNA.

1989 • 301 citations

Subunit-selective mutagenesis indicates minimal polymerase activity in heterodimer-associated p51 HIV-1 reverse transcriptase.

1991 • 208 citations

Dimerization of human immunodeficiency virus type 1 reverse transcriptase. A target for chemotherapeutic intervention.

1990 • 183 citations

A novel, dipyridodiazepinone inhibitor of HIV-1 reverse transcriptase acts through a nonsubstrate binding site

1991 • 180 citations

Reverse transcriptase of human immunodeficiency virus type 1: functionality of subunits of the heterodimer in DNA synthesis

1992 • 96 citations

Modulation of HIV-1 reverse transcriptase function in “selectively deleted” p66/p51 heterodimers.

1994 • 58 citations

Characterization of the dimerization process of HIV‐1 reverse transcriptase heterodimer using intrinsic protein fluorescence

1993 • 41 citations

HIV-1 reverse transcriptase: Polymerization properties of the p51 homodimer compared to the p66/p51 heterodimer

1993 • 30 citations

Two DNA Polymerases: HIV Reverse Transcriptase and the Klenow Fragment of Escherichia coli DNA Polymerase I

1993 • 27 citations