Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA

Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)

1983 • 6,811 citations

[19] Rapid and efficient site-specific mutagenesis without phenotypic selection

1987 • 5,413 citations

Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDS

1984 • 3,647 citations

Improved retroviral vectors for gene transfer and expression.

1989 • 1,997 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Simple RNA enzymes with new and highly specific endoribonuclease activities

1988 • 1,118 citations

A small catalytic oligoribonucleotide

1987 • 938 citations

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

1986 • 828 citations

Ribozymes as Potential Anti-HIV-1 Therapeutic Agents

1990 • 663 citations

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

1987 • 660 citations

The trans-activator gene of HTLV-III is essential for virus replication

1986 • 635 citations

The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

1986 • 615 citations

Location of the Trans -Activating Region on the Genome of Human T-Cell Lymphotropic Virus Type III

1985 • 558 citations

The Chemistry of Self-Splicing RNA and RNA Enzymes

1987 • 523 citations

Overexpression of TAR sequences renders cells resistant to human immunodeficiency virus replication

1990 • 437 citations

Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vector.

1989 • 359 citations

Effect of internal viral sequences on the utility of retroviral vectors

1987 • 351 citations

Resistance to human immunodeficiency virus type 1 (HIV-1) infection in human CD4+ lymphocyte-derived cell lines conferred by using retroviral vectors expressing an HIV-1 RNA-specific ribozyme

1991 • 156 citations

Human T-cell leukemia virus-associated membrane antigens: identity of the major antigens recognized after virus infection.

1984 • 119 citations

Inhibition of human immunodeficiency virus (HIV) replication by HIV-trans-activated alpha 2-interferon.

1989 • 95 citations

Inhibition of human immunodeficiency virus type 1 multiplication by antisense and sense RNA expression

1991 • 87 citations

Inhibition of human immunodeficiency virus replication in cell culture by endogenously synthesized antisense RNA

1990 • 80 citations

A tripartite HIV-1 tat-env-rev fusion protein.

1990 • 79 citations

Retroviral Vectors Expressing Soluble CD4: A Potential Gene Therapy for AIDS

1990 • 51 citations

Inhibition of heterologous strains of HIV by antisense RNA

1991 • 40 citations