Human Papillomavirus Type 31 Replication Modes during the Early Phases of the Viral Life Cycle Depend on Transcriptional and Posttranscriptional Regulation of E1 and E2 Expression

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter.

1982 • 2,753 citations

Tumorigenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinomas.

1981 • 743 citations

Complex splicing patterns of RNAs from the early regions of adenovirus-2

1979 • 560 citations

Transient replication of BPV-1 requires two viral polypeptides encoded by the E1 and E2 open reading frames.

1991 • 462 citations

Transactivation of a bovine papilloma virus transcriptional regulatory element by the E2 gene product

1985 • 402 citations

Targeting the E1 Replication Protein to the Papillomavirus Origin of Replication by Complex Formation with the E2 Transactivator

1990 • 396 citations

Transcriptional regulation of the human papillomavirus-16 E6-E7 promoter by a keratinocyte-dependent enhancer, and by viral E2 trans-activator and repressor gene products: implications for cervical carcinogenesis.

1987 • 327 citations

Viral E1 and E2 proteins support replication of homologous and heterologous papillomaviral origins.

1992 • 302 citations

The BPV1-E2 trans-acting protein can be either an activator or a repressor of the HPV18 regulatory region.

1987 • 294 citations

Activation of BPV-1 replication in vitro by the transcription factor E2

1991 • 284 citations

A transcriptional repressor encoded by BPV-1 shares a common carboxy-terminal domain with the E2 transactivator

1987 • 278 citations

Differentiation-induced and constitutive transcription of human papillomavirus type 31b in cell lines containing viral episomes

1992 • 267 citations

Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

1998 • 220 citations

In vitro synthesis of oncogenic human papillomaviruses requires episomal genomes for differentiation-dependent late expression.

1996 • 198 citations

Human papillomavirus type 31 oncoproteins E6 and E7 are required for the maintenance of episomes during the viral life cycle in normal human keratinocytes

1999 • 198 citations

Dose-dependent regulation of the early promoter of human papillomavirus type 18 by the viral E2 protein

1997 • 187 citations

Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene.

1987 • 138 citations

Bovine papilloma virus plasmids replicate randomly in mouse fibroblasts throughout S phase of the cell cycle

1987 • 135 citations

The E8^E2C Protein, a Negative Regulator of Viral Transcription and Replication, Is Required for Extrachromosomal Maintenance of Human Papillomavirus Type 31 in Keratinocytes

2000 • 130 citations

Transcriptional control of human papillomavirus (HPV) oncogene expression: composition of the HPV type 18 upstream regulatory region

1993 • 122 citations

Cell-free replication of the human papillomavirus DNA with homologous viral E1 and E2 proteins and human cell extracts.

1994 • 120 citations

Temporal Usage of Multiple Promoters during the Life Cycle of Human Papillomavirus Type 31b

1998 • 116 citations

Binding of the E1 and E2 proteins to the origin of replication of bovine papillomavirus

1997 • 112 citations

Nucleotide sequence of human papillomavirus type 31: A cervical neoplasia-associated virus

1989 • 107 citations

Control of human papillomavirus type 11 origin of replication by the E2 family of transcription regulatory proteins

1992 • 99 citations

Bovine papillomavirus type 1 3' early region transformation and plasmid maintenance functions

1986 • 97 citations

Transactivation by the E2 Protein of Oncogenic Human Papillomavirus Type 31 Is Not Essential for Early and Late Viral Functions

1998 • 93 citations

Differential Requirements for Conserved E2 Binding Sites in the Life Cycle of Oncogenic Human Papillomavirus Type 31

1998 • 92 citations

The Role of the E1 and E2 Proteins in the Replication of Human Papillomavirus Type 31b

1994 • 89 citations

The Functions of Human Papillomavirus Type 11 E1, E2, and E2C Proteins in Cell-free DNA Replication

1995 • 88 citations

Differentiation-Induced Changes in Promoter Usage for Transcripts Encoding the Human Papillomavirus Type 31 Replication Protein E1

1999 • 77 citations

Replication of human papillomavirus (HPV) DNAs supported by the HPV type 18 E1 and E2 proteins

1994 • 75 citations

Phenotypic analysis of bovine papillomavirus type 1 E2 repressor mutants

1990 • 75 citations

Genetic assignment of multiple E2 gene products in bovine papillomavirus-transformed cells

1989 • 73 citations

Human papillomavirus type 31b late gene expression is regulated through protein kinase C-mediated changes in RNA processing

1995 • 73 citations

Expression of AP1 during cellular differentiation determines human papillomavirus E6/E7 expression in stratified epithelial cells.

1997 • 73 citations

Cooperative assembly of the bovine papilloma virus E1 and E2 proteins on the replication origin requires an intact E2 binding site

1993 • 72 citations

Human Papillomavirus Type 18 E1 Protein Is Translated from Polycistronic mRNA by a Discontinuous Scanning Mechanism

1999 • 69 citations

The bovine papillomavirus P2443 promoter is E2 trans-responsive: evidence for E2 autoregulation.

1988 • 65 citations

Translation of the human papillomavirus type 16 E7 oncoprotein from bicistronic mRNA is independent of splicing events within the E6 open reading frame

1995 • 65 citations

DNA Replication of Human Papillomavirus Type 31 Is Modulated by Elements of the Upstream Regulatory Region That Lie 5′ of the Minimal Origin

1999 • 63 citations

E1 protein of human papillomavirus type 1a is sufficient for initiation of viral DNA replication.

1994 • 63 citations

Transcription Factor-dependent Loading of the E1 Initiator Reveals Modular Assembly of the Papillomavirus Origin Melting Complex

2000 • 56 citations

Random-choice replication of extrachromosomal bovine papillomavirus (BPV) molecules in heterogeneous, clonally derived BPV-infected cell lines

1992 • 46 citations

Characterization of the cis elements involved in basal and E2-transactivated expression of the bovine papillomavirus P2443 promoter

1991 • 43 citations

The 5′ Region of the Human Papillomavirus Type 31 Upstream Regulatory Region Acts as an Enhancer Which Augments Viral Early Expression Through the Action of YY1

1997 • 40 citations

Two Novel Promoters in the Upstream Regulatory Region of Human Papillomavirus Type 31b Are Negatively Regulated by Epithelial Differentiation

1999 • 35 citations

Differential effects of the splice acceptor at nucleotide 3295 of human papillomavirus type 31 on stable and transient viral replication

1997 • 26 citations

SV40 Small T Antigen Enhances Progression to >G2 during Lytic Infection

1999 • 17 citations

Identification and genetic definition of a bovine papillomavirus type 1 E7 protein and absence of a low-copy-number phenotype exhibited by E5, E6, or E7 viral mutants

1992 • 15 citations

Control of adenovirus alternative RNA splicing: effect of viral DNA replication on RNA splice site choice

1991 • 14 citations

Bovine papillomavirus type 4

1996 • 12 citations

A High Capacity Assay for Inhibitors of Human Papillomavirus DNA Replication

1995 • 11 citations

Regulation of SV40 Gene Expression through RNA Splicing

1980 • 11 citations

Sp1 is critical for basal and E2-transactivated transcription from the bovine papillomavirus type 1 P89 promoter

1996 • 10 citations

Introduction to simian virus 40: getting by with more than a little help from its host cell.

1998 • 9 citations

Splice sites of human papillomavirus type 16 E6 gene or heterologous gene required for transformation by E7 and accumulation of E7 RNA

1995 • 8 citations

Importance of the bovine papillomavirus P2443 promoter in the regulation of E2 and E5 expression

1993 • 4 citations