Bilirubin directly disrupts membrane lipid polarity and fluidity, protein order, and redox status in rat mitochondria

Mitochondria and Apoptosis

1998 • 8,909 citations

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

1997 • 7,177 citations

Caspases: Enemies Within

1998 • 6,923 citations

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

1996 • 5,133 citations

Prevention of Apoptosis by Bcl-2: Release of Cytochrome c from Mitochondria Blocked

1997 • 4,921 citations

The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis

1997 • 4,728 citations

Mitochondrial cytochrome c release in apoptosis occurs upstream of DEVD-specific caspase activation and independently of mitochondrial transmembrane depolarization

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The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant

2000 • 1,046 citations

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation.

1998 • 523 citations

β-Amyloid Peptide Free Radical Fragments Initiate Synaptosomal Lipoperoxidation in a Sequence-Specific Fashion: Implications to Alzheimer′s Disease

1994 • 406 citations

Ursodeoxycholic Acid May Inhibit Deoxycholic Acid-Induced Apoptosis by Modulating Mitochondrial Transmembrane Potential and Reactive Oxygen Species Production

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Lipid spin labels in lecithin multilayers. A study of motion along fatty acid chains

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Bilirubin. Solubility and interaction with albumin and phospholipid

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Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis.

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Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

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The ready isomerization of bilirubin IX-α in aqueous solution

1972 • 232 citations

Ursodeoxycholate (UDCA) inhibits the mitochondrial membrane permeability transition induced by glycochenodeoxycholate: a mechanism of UDCA cytoprotection.

1995 • 231 citations

Bcl‐2 Protects Isolated Plasma and Mitochondrial Membranes Against Lipid Peroxidation Induced by Hydrogen Peroxide and Amyloid β‐Peptide

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Effects of Bilirubin on Mitochondrial Reactions

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Bilirubin Induces Apoptosis via Activation of NMDA Receptors in Developing Rat Brain Neurons

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Bilirubin and Amyloid-β Peptide Induce Cytochrome c Release Through Mitochondrial Membrane Permeabilization

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Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid

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The Mechanism of Bilirubin Toxicity Studied with Purified Respiratory Enzyme and Tissue Culture Systems^*

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Inhibition of Glutamate Uptake by Unconjugated Bilirubin in Cultured Cortical Rat Astrocytes: Role of Concentration and pH

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Tauroursodeoxycholic Acid Partially Prevents Apoptosis Induced by 3‐Nitropropionic Acid

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Electron paramagnetic resonance investigations of free radical-induced alterations in neocortical synaptosomal membrane protein infrastructure

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Bile pigments and jaundice

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Effect of lipid membranes on the apparent pK of the local anesthetic tetracaine spin label and titration studies

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Mode of Inhibitory Action of Bilirubin on Protein Kinase C

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Bile pigments and jaundice

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Deposition of Bilirubin Acid in the Central Nervous System–A Hypothesis for the Development of Kernicterus

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Bilirubin: A multi‐site inhibitor of mitochondrial respiration

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Bilirubin Decreases Phosphorylation of Synapsin I, a Synaptic Vesicle-Associated Neuronal Phosphoprotein, in Intact Synaptosomes from Rat Cerebral Cortex

1988 • 57 citations

Bilirubin Toxicity in Neural Cell Lines N115 and NBR10A

1985 • 50 citations

Bilirubin-Induced Modulation of Cerebral Protein Phosphorylation in Neonate Rabbits in Vivo

1982 • 49 citations

Effect of Bilirubin on the Membrane Potential of Rat Brain Synaptosomes

1986 • 47 citations

Mechanism of the spontaneous transfer of unconjugated bilirubin between small unilamellar phosphatidylcholine vesicles

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Effects of Bilirubin Molecular Species on Membrane Dynamic Properties of Human Erythrocyte Membranes: A Spin Label Electron Paramagnetic Resonance Spectroscopy Study

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The role of the matrix calcium level in the enhancement of mitochondrial pyruvate carboxylation by glucagon pretreatment.

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Structure and flexibility of plasma fibronectin in solution: electron spin resonance spin-label, circular dichroism and sedimentation studies

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Impairment of DNA synthesis in Gunn rat cerebellum

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Use of membrane spin label spectra to monitor rates of reaction of partitioning compounds: Hydrolysis of a local anesthetic analog

1988 • 26 citations

The effect of bile salts and calcium on isolated rat liver mitochondria

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An Electron-Spin-Resonance Spin-Label Study of the Interaction of Purified Mojave Toxin with Synaptosomal Membranes from Rat Brain

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Ultrastructure of the Gunn rat substantia nigra

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A Neurophysiological Study in Children and Adolescents with Crigler-Najjar Syndrome Type I

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Covalent attachment of sulfhydryl-specific, electron spin resonance (ESR) spin-labels to Fab' fragments of murine monoclonal antibodies that recognize human platelet membrane glycoproteins. Ddevelopment of membrane protein-specific spin probes

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Bilirubin encephalopathy: effect on RNA polymerase activity and chromatin template activity in the brain of the Gunn rat.

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