Effects of cyclosporin A and FK506 on Fc epsilon receptor type I-initiated increases in cytokine mRNA in mouse bone marrow-derived progenitor mast cells: resistance to FK506 is associated with a deficiency in FK506-binding protein FKBP12.

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Current protocols in molecular biology

1988 • 4,543 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics

1988 • 1,699 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance

1986 • 1,305 citations

Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A.

1992 • 811 citations

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

1989 • 667 citations

Interleukin 3-dependent and -independent mast cells stimulated with IgE and antigen express multiple cytokines.

1989 • 557 citations

N-Acetyl-β-glucosaminidases in human spleen

1968 • 523 citations

Fate of bone marrow-derived cultured mast cells after intracutaneous, intraperitoneal, and intravenous transfer into genetically mast cell-deficient W/Wv mice. Evidence that cultured mast cells can give rise to both connective tissue type and mucosal mast cells.

1985 • 503 citations

Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development.

1983 • 476 citations

Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation.

1987 • 416 citations

Two cytoplasmic candidates for immunophilin action are revealed by affinity for a new cyclophilin: One in the presence and one in the absence of CsA

1991 • 399 citations

Interleukin 3: A differentiation and growth factor for the mouse mast cell that contains chondroitin sulfate E proteoglycan.

1984 • 390 citations

Human cyclophilin B: a second cyclophilin gene encodes a peptidyl-prolyl isomerase with a signal sequence.

1991 • 319 citations

Molecular cloning and overexpression of the human FK506-binding protein FKBP

1990 • 316 citations

cDNA cloning of murine interleukin-HP1: homology with human interleukin 6

1988 • 292 citations

Two interleukin 1 genes in the mouse: cloning and expression of the cDNA for murine interleukin 1 beta.

1986 • 267 citations

Differential release of serotonin and histamine from mast cells

1982 • 238 citations

Homology of the rat basophilic leukemia cell and the rat mucosal mast cell.

1985 • 227 citations

IgE-mediated release of leukotriene C4, chondroitin sulfate E proteoglycan, beta-hexosaminidase, and histamine from cultured bone marrow-derived mouse mast cells.

1983 • 201 citations

Thirteen hybridomas secreting hapten‐specific immunoglobulin E from mice with Ig^a or Ig^b heavy chain haplotype

1981 • 201 citations

Molecular cloning of a membrane-associated human FK506- and rapamycin-binding protein, FKBP-13.

1991 • 173 citations

Cyclosporin-mediated inhibition of bovine calcineurin by cyclophilins A and B.

1992 • 168 citations

Immunosuppression of canine, monkey, and baboon allografts by FK 506: with special reference to synergism with other drugs and to tolerance induction.

1988 • 160 citations

Immunophilin ligands demonstrate common features of signal transduction leading to exocytosis or transcription.

1991 • 123 citations

FK-506, a potent novel inhibitor of the release of proinflammatory mediators from human Fc epsilon RI+ cells.

1991 • 118 citations

Intestinal mucosal mast cells from rats infected with Nippostrongylus brasiliensis contain protease-resistant chondroitin sulfate di-B proteoglycans.

1986 • 116 citations

Purification and characterization of protease-resistant secretory granule proteoglycans containing chondroitin sulfate di-B and heparin-like glycosaminoglycans from rat basophilic leukemia cells.

1985 • 101 citations

Phenotypic changes of bone marrow-derived mast cells after intraperitoneal transfer into W/Wv mice that are genetically deficient in mast cells.

1987 • 97 citations

Differential release of serotonin without comparable histamine under diverse conditions in the rat mast cell

1985 • 78 citations

Cyclosporin A inhibits degranulation of rat basophilic leukemia cells and human basophils. Inhibition of mediator release without affecting PI hydrolysis or Ca2+ fluxes.

1990 • 62 citations

The requirements for triggering of lysis by cytolytic T lymphocyte clones. II. Cyclosporin A inhibits TCR-mediated exocytosis by only selectively inhibits TCR-mediated lytic activity by cloned CTL.

1989 • 58 citations

FK-506 and cyclosporin a: Selective inhibition of calcium ionophore-induced polymorphonuclear leukocyte degranulation

1991 • 38 citations

Inhibitory Effect of Cyclosporin A on Histamine Release from Human Leukocytes and Rat Mast Cells

1985 • 35 citations

Effect of Cyclosporin A on Human Neutrophil and Monocyte Function

1985 • 31 citations

Mast cell biochemical and functional heterogeneity.

1991 • 17 citations