Antioxidant Effect of Cysteamine in Brain Cortex of Young Rats

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

1979 • 27,693 citations

[13] Catalase in vitro

1984 • 22,648 citations

[49] Determination of carbonyl content in oxidatively modified proteins

1990 • 5,654 citations

[44] Glutathione peroxidase

1981 • 2,990 citations

Evaluation of the probe 2',7'-dichlorofluorescin as an indicator of reactive oxygen species formation and oxidative stress

1992 • 2,536 citations

[38] Oxidative damage to proteins: Spectrophotometric method for carbonyl assay

1994 • 2,372 citations

Redefining Oxidative Stress

2006 • 1,587 citations

SPSS for intermediate statistics : use and interpretation

2005 • 1,548 citations

The Haber–Weiss reaction and mechanisms of toxicity

2000 • 1,301 citations

Superoxide radical inhibits catalase.

1982 • 1,274 citations

Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide

1999 • 769 citations

Lysosomal Membrane Permeabilization Induces Cell Death in a Mitochondrion-dependent Fashion

2003 • 449 citations

A Specific and Sensitive Assay for Disulfides

1968 • 446 citations

Hydroperoxide-initiated chemiluminescence: An assay for oxidative stress in biopsies of heart, liver, and muscle

1991 • 446 citations

Cystinosis. Intracellular cystine depletion by aminothiols in vitro and in vivo.

1976 • 331 citations

Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control

2004 • 288 citations

Cellular titration of apoptosis with steady state concentrations of H2O2: submicromolar levels of H2O2 induce apoptosis through fenton chemistry independent of the cellular thiol state

2001 • 246 citations

Extracellular Redox State: Refining the Definition of Oxidative Stress in Aging

2006 • 236 citations

4-hydroxynonenal induces a cellular redox status-related activation of the caspase cascade for apoptotic cell death

2000 • 215 citations

Creatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activity

2005 • 204 citations

Comparison of Lipid Peroxidation and Myocardial Damage Induced by Adriamycin and 4′-Epiadriamycin in Mice

1985 • 201 citations

Lysosomal Cystine Storage Augments Apoptosis in Cultured Human Fibroblasts and Renal Tubular Epithelial Cells

2002 • 166 citations

Discovery and Characterization of a Second Mammalian Thiol Dioxygenase, Cysteamine Dioxygenase

2007 • 163 citations

Histidine and lysine as targets of oxidative modification

2003 • 150 citations

Cystamine increases <scp>l</scp>‐cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation

2004 • 118 citations

Myopathy and Cystine Storage in Muscles in a Patient with Nephropathic Cystinosis

1988 • 114 citations

Oxidant-Induced Apoptosis in Human Retinal Pigment Epithelial Cells: Dependence on Extracellular Redox State

2005 • 106 citations

Early oral cysteamine therapy for nephropathic cystinosis

2003 • 102 citations

Thiol Oxidase Activity of Copper,Zinc Superoxide Dismutase

2002 • 101 citations

Ophthalmic Manifestations and Histopathology of Infantile Nephropathic Cystinosis: Report of a Case and Review of the Literature

2007 • 97 citations

Intracellular Redox State Determines Whether Nitric Oxide Is Toxic or Protective to Rat Oligodendrocytes in Culture

1999 • 86 citations

Increased Apoptosis in Cystinotic Fibroblasts and Renal Proximal Tubule Epithelial Cells Results from Cysteinylation of Protein Kinase Cδ

2006 • 78 citations

Nephropathic Cystinosis

2006 • 77 citations

Nephropathic cystinosis with central nervous system involvement

1987 • 72 citations

Cortical atrophy and cognitive performance in infantile nephropathic cystinosis

1990 • 72 citations

Disulphide reduction in lysosomes. The role of cysteine

1986 • 67 citations

Central Nervous System Involvement in Nephropathic Cystinosis

1990 • 65 citations

Detection and Characterization of a Transport System Mediating Cysteamine Entry into Human Fibroblast Lysosomes

1995 • 50 citations

Effect of cystine dimethylester on renal solute handling and isolated renal tubule transport in the rat: A new model of the fanconi syndrome

1987 • 49 citations

Cellular thiol pools are responsible for sequestration of cytotoxic reactive aldehydes: Central role of free cysteine and cysteamine

2007 • 43 citations

Potential role of apoptosis in development of the cystinotic phenotype

2004 • 42 citations

Metabolic studies of rat renal tubule cells loaded with cystine

1995 • 36 citations

Inhibition of tumor necrosis factor‐induced apoptosis in transgenic mouse liver expressing creatine kinase

2004 • 34 citations

Cystine loading induces Fanconi's syndrome in rats: in vivo and vesicle studies

1993 • 32 citations

Lysosomal Storage Diseases: Is Impaired Apoptosis a Pathogenic Mechanism?

2004 • 31 citations

Academic achievement in individuals with infantile nephropathic cystinosis

1997 • 31 citations

The in Vivo Use of Dithiothreitol in Cystinosis

1977 • 25 citations

Inhibition of pyruvate kinase activity by cystine in brain cortex of rats

2004 • 22 citations

Cysteamine prevents and reverses the inhibition of creatine kinase activity caused by cystine in rat brain cortex

2005 • 19 citations

Action of Cystine in the Cytotoxic Response of Escherichia Coli Cells Exposed to Hydrogen Peroxide

1995 • 14 citations

Promotion of oxidative stress in kidney of rats loaded with cystine dimethyl ester

2007 • 14 citations

Cystinosis

2002 • 13 citations

Metabolism of cysteamine.

1957 • 9 citations