Loss of heterozygosity at chromosome 13q in hepatocellular carcinoma: identification of three independent regions

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Identification of the breast cancer susceptibility gene BRCA2

1995 • 3,581 citations

A comprehensive genetic map of the human genome based on 5,264 microsatellites

1996 • 2,983 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

M6P/IGF2R gene is mutated in human hepatocellular carcinomas with loss of heterozygosity

1995 • 352 citations

Allele loss on chromosome 16 associated with progression of human hepatocellular carcinoma.

1990 • 292 citations

Comprehensive allelotyping of human hepatocellular carcinoma

1997 • 285 citations

Frequent loss of heterozygosity on 6q at the mannose 6-phosphate/insulin-like growth factor II receptor locus in human hepatocellular tumors.

1995 • 189 citations

Deletions of chromosome 13q, mutations in Retinoblastoma 1, and retinoblastoma protein state in human hepatocellular carcinoma.

1994 • 170 citations

Deletions in human chromosome arms 11p and 13q in primary hepatocellular carcinomas

1988 • 161 citations

Hepatitis C and B viruses in hepatitis B Surface antigen-negative hepatocellular carcinoma

1992 • 137 citations

Inactivation of the retinoblastoma susceptibility gene in non-small-cell lung cancer. The Lung Cancer Study Group.

1993 • 128 citations

Alterations of tumor suppressor genes and allelic losses in human hepatocellular carcinomas in China.

1994 • 125 citations

Frequent genetic alterations at the distal region of chromosome 1p in human hepatocellular carcinomas.

1994 • 122 citations

Altered messenger RNA and unique mutational profiles of p53 and Rb in human esophageal carcinomas.

1993 • 118 citations

Frequent Loss of Heterozygosity on Chromosomes 16 and 4 in Human Hepatocellular Carcinoma

1990 • 116 citations

Isolation of a candidate tumor suppressor gene on chromosome 8p21.3-p22 that is homologous to an extracellular domain of the PDGF receptor beta gene.

1995 • 101 citations

Hepatitis B Virus Infection, Its Sequelae, and Prevention in Taiwan

1987 • 97 citations

Allelic loss on chromosomes 4q and 16q in hepatocellular carcinoma: Association with elevated alpha-fetoprotein production

1996 • 94 citations

Loss of heterozygosity on chromosome 13 is common only in the biologically more aggressive subtypes of ovarian epithelial tumors and is associated with normal retinoblastoma gene expression.

1994 • 77 citations

Deletion of the E-cadherin gene in hepatitis B virus-positive chinese hepatocellular carcinomas

1993 • 74 citations

Allelic loss of chromosome 13q14.3 in human oral cancer: Correlation with lymph node metastasis

1998 • 73 citations

p53 gene mutations and 17p allelic deletions in hepatocellular Carcinoma from Japan

1993 • 72 citations

Liver cell cancer

1976 • 72 citations

Mutation of p53 gene in hepatocellular carcinoma in Taiwan.

1992 • 72 citations

Evidence for the presence of two tumour-suppressor genes for hepatocellular carcinoma on chromosome 13q

1995 • 65 citations

Molecular Genetic Studies of Tumor suppressor Gene Regions on chromosomes 13 and 17 in Colorectal Tumors

1992 • 53 citations

Rearrangement of a common cellular DNA domain on chromosome 4 in human primary liver tumors

1988 • 52 citations

Chromosomal abnormality in hepatocellular carcinoma by comparative genomic hybridisation in Taiwan

1999 • 50 citations

THE GEOGRAPHIC PATHOLOGY OF LIVER CELL CANCER

1976 • 34 citations

Interstitial chromosomal deletion within 4q11-q13 in a human hepatoma cell line.

1991 • 26 citations

Frequent allelic losses on chromosome 13q in human male breast carcinomas

1997 • 10 citations