The lipophosphoglycan of Leishmania

CELL-SURFACE ANCHORING OF PROTEINS VIA GLYCOSYL-PHOSPHATIDYLINOSITOL STRUCTURES

1988 • 1,284 citations

Structural and Functional Roles of Glycosyl-Phosphatidylinositol in Membranes

1988 • 963 citations

Glycosyl-Phosphatidylinositol Moiety That Anchors Trypanosoma brucei Variant Surface Glycoprotein to the Membrane

1988 • 701 citations

The glycosyl-phosphatidylinositol anchor of membrane proteins

1989 • 520 citations

Identification of an Infective Stage of Leishmania Promastigotes

1984 • 498 citations

Receptors for C3b and C3bi promote phagocytosis but not the release of toxic oxygen from human phagocytes.

1983 • 495 citations

Complete structure of the glycosyl phosphatidylinositol membrane anchor of rat brain Thy-1 glycoprotein

1988 • 447 citations

Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes.

1985 • 338 citations

Mechanisms for the removal of benzyl protecting groups in synthetic peptides by trifluoromethanesulfonic acid-trifluoroacetic acid-dimethyl sulfide

1986 • 281 citations

Susceptibility of leishmania to oxygen intermediates and killing by normal macrophages

1981 • 267 citations

CR1, the C3b receptor, mediates binding of infective Leishmania major metacyclic promastigotes to human macrophages.

1989 • 258 citations

Microbial glycolipids: possible virulence factors that scavenge oxygen radicals.

1989 • 255 citations

Effective immunization against cutaneous leishmaniasis with defined membrane antigens reconstituted into liposomes.

1988 • 236 citations

The Leishmania receptor for macrophages is a lipid-containing glycoconjugate.

1985 • 235 citations

Structure of the lipid moiety of the Leishmania donovani lipophosphoglycan.

1987 • 228 citations

Metacyclogenesis in Leishmania promastigotes

1989 • 215 citations

Complement binding by two developmental stages of Leishmania major promastigotes varying in expression of a surface lipophosphoglycan.

1988 • 202 citations

Scavenging by alginate of free radicals released by macrophages

1989 • 186 citations

Lipophosphoglycan of Leishmania major that vaccinates against cutaneous leishmaniasis contains an alkylglycerophosphoinositol lipid anchor.

1987 • 184 citations

Two transduction sequences are necessary for neutrophil activation by receptor agonists.

1988 • 172 citations

Circulating antibodies to mouse laminin in Chagas disease, American cutaneous leishmaniasis, and normal individuals recognize terminal galactosyl(alpha 1-3)-galactose epitopes.

1987 • 170 citations

Immunization with Leishmania receptor for macrophages protects mice against cutaneous leishmaniasis.

1985 • 145 citations

The generation of infective stage Leishmania major promastigotes is associated with the cell-surface expression and release of a developmentally regulated glycolipid.

1987 • 141 citations

Structure of the major carbohydrate fragment of the Leishmania donovani lipophosphoglycan

1987 • 139 citations

A Family of Glycoinositol Phospholipids from Leishmania major

1989 • 134 citations

Phagocytosis and killing of the protozoan Leishmania donovani by human polymorphonuclear leukocytes.

1981 • 132 citations

Inhibitory effects on protein kinase C activity by lipophosphoglycan fragments and glycosylphosphatidylinositol antigens of the protozoan parasite Leishmania

1989 • 131 citations

Leishmanial serotypes as distinguished by the gel diffusion of factors excreted in vitro and in vivo.

1972 • 128 citations

Structure of the Phosphosaccharide-inositol Core of the Leishmania donovani Lipophosphoglycan

1989 • 127 citations

Passive transfer of Leishmania lipopolysaccharide confers parasite survival in macrophages.

1986 • 127 citations

An amphipathic sulphated glycoconjugate of Leishmania: characterization with monoclonal antibodies.

1984 • 125 citations

C3 binds preferentially to long-chain lipopolysaccharide during alternative pathway activation by Salmonella montevideo.

1986 • 124 citations

Monoclonal antibodies to Leishmania tropica major: specificities and antigen location

1982 • 121 citations

Leishmania and the macrophage: a marriage of inconvenience

1989 • 117 citations

The immunochemical structure and surface arrangement of Leishmania donovani lipophosphoglycan determined using monoclonal antibodies

1989 • 116 citations

Impairment of the oxidative metabolism of mouse peritoneal macrophages by intracellular Leishmania spp

1987 • 107 citations

Expression of an unusual acidic glycoconjugate in Leishmania donovani.

1984 • 107 citations

Lipid analyses of isolated surface membranes ofLeishmania Donovani promastigotes

1985 • 105 citations

Inhibition of protein kinase C activity by the Leishmaniadonovani lipophosphoglycan

1987 • 96 citations

Leishmania donovani metacyclic promastigotes: Transformation in vitro, lectin agglutination, complement resistance, and infectivity

1987 • 90 citations

c-fos and tumor necrosis factor gene expression in Leishmania donovani-infected macrophages.

1989 • 87 citations

A ricin agglutinin-resistant clone of Leishmania donovani deficient in lipophosphoglycan

1988 • 86 citations

Infectivity of Leishmania braziliensis promastigotes is dependent on the increasing expression of a 65,000-dalton surface antigen.

1987 • 84 citations

Effects of Promastigote Growth Phase, Frequency of Subculture, and Host Age on Promastigote‐initiated Infections with Leishmania donovani in the Golden Hamster*^†

1974 • 83 citations

Cell surface lipophosphoglycan of Leishmania donovani

1987 • 77 citations

Rapid lateral diffusion of the variant surface glycoprotein in the coat of Trypanosoma brucei

1988 • 73 citations

Leishmania donovani: Action of excreted factor on hydrolytic enzyme activity of macrophages from mice with genetically different resistance to infection

1980 • 70 citations

Chemical structure and antigenic aspects of complexes obtained from epimastigotes of Trypanosoma cruzi

1983 • 70 citations

Inhibition of Leishmania donovani promastigote internalization into murine macrophages by chemically defined parasite glycoconjugate ligands

1989 • 68 citations

Characterization of inositol lipids from Leishmania donovani promastigotes: identification of an inositol sphingophospholipid.

1990 • 68 citations

The influence of hydrolysates of hyaluronate upon hyaluronidase production by micro-organisms

1946 • 63 citations

Leishmania donovani: Physicochemical, immunological, and biological characterization of excreted factor from promastigotes

1979 • 57 citations

Evidence of T-cell recognition in mice of a purified lipophosphoglycan from Leishmania major

1989 • 57 citations

Leishmania major: Excreted factor, calcium ions, and the survival of amastigotes

1985 • 57 citations

Structural Analysis of Glycosyl-phosphatidylinositol Antigens of Leishmania major

1989 • 51 citations

Expression of Leishmania antigen on the surface membrane of infected human macrophages in vitro.

1981 • 48 citations

Receptors and recognition mechanisms of Leishmania species

1985 • 46 citations

Serological activity against galactosyl-alpha(1-3)galactose in sera from patients with several kinetoplastida infections

1988 • 46 citations

Leishmanial Excreted Factor: Protein-Bound and Free Forms from Promastigote Cultures of Leishmania tropica and Leishmania donovani

1979 • 45 citations

Monoclonal antibodies for serotyping Leishmania strains

1983 • 44 citations

Lipopeptidophosphoglycan from Trypanosoma cruzi

1977 • 42 citations

Cell surface nanoanatomy of Leishmania major as revealed by fracture-flip. A surface meshwork of 44 nm fusiform filaments identifies infective developmental stage promastigotes.

1989 • 42 citations

The glycosylphosphatidylinositol membrane anchor of Trypanosoma brucei variant surface glycoprotein

1988 • 42 citations

A Carbohydrate-Containing Antigen from Trypanosoma cruzi and Its Detection in the Circulation of Infected Mice

1977 • 41 citations

Infectivity of Leishmania donovani Amastigotes and Promastigotes for Golden Hamsters*

1976 • 41 citations

Cell surface origin of antigens shed by Leishmania donovani during growth in axenic culture

1982 • 40 citations

[13] Inositol-containing sphingolipids

1987 • 37 citations

The detection of phosphonolipids in the protozoan Trypanosoma cruzi

1982 • 37 citations

Leishmania major: glycolipid antigens recognized by immune human sera

1988 • 35 citations

Action of leishmanial excreted factor (EF) on human lymphocyte blast transformation

1983 • 32 citations

Identification and recovery of Leishmania antigen displayed on the surface membrane of mouse peritoneal macrophages infected in vitro.

1986 • 31 citations

The Role of Polysaccharide in the Secretion of Protein by Micrococcus sodonensis

1974 • 30 citations

Immunochemical characterization of a glyco-inositol-phospholipid membrane antigen of Leishmania major.

1988 • 26 citations

Persistence of elevated levels of galactosyl-alpha(1-3)galactose antibodies in sera from patients cured of visceral leishmaniasis

1988 • 24 citations

Partial chemical characterization of the carbohydrate moieties in Leishmania adleri glycoconjugates

1985 • 23 citations

Endogenous and surface labeling of glycoconjugates from the three differentiation stages of Trypanosoma cruzi

1982 • 22 citations

Characterization of the exometabolite of Leishmaniadonovani as a novel glycopeptidophosphosphingolipid

1981 • 21 citations

Lipid and Lipopolysaccharide‐Like Antigens of Leishmania Promastigotes1

1985 • 18 citations

Leishmania major: a very sensitive dot-blot ELISA for detection of parasites in cutaneous lesions.

1987 • 11 citations

Leptomonas samueli glycoconjugates. Comparison with Herpetomonas samuelpessoai

1987 • 10 citations

Cell-mediated responses and protection elicited by a carbohydrate-lipid-containing fraction extracted from Leishmania major promastigotes

1988 • 6 citations

Presence of a lipophosphoglycan in two variants of trypanosoma brucei brucei

1988 • 6 citations

Trypanosoma cruzi: aminoacid and phosphorus linkages in the lipopeptidophosphoglycan.

1985 • 4 citations