Fc gamma RII/III and CD2 expression mark distinct subpopulations of immature CD4-CD8- murine thymocytes: in vivo developmental kinetics and T cell receptor beta chain rearrangement status.

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

RAG-1-deficient mice have no mature B and T lymphocytes

1992 • 2,859 citations

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1992 • 2,618 citations

Xenogeneic Monoclonal Antibodies to Mouse Lymphoid Differentiation Antigens*

1979 • 1,989 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

RAG-1 and RAG-2, Adjacent Genes That Synergistically Activate V(D)J Recombination

1990 • 1,450 citations

Characterization of a monoclonal antibody directed against mouse macrophage and lymphocyte Fc receptors.

1979 • 1,301 citations

Fc Receptors

1991 • 1,220 citations

The V(D)J recombination activating gene, RAG-1

1989 • 1,164 citations

Mutations in T-cell antigen receptor genes α and β block thymocyte development at different stages

1992 • 1,116 citations

Characterization of the Murine Antigenic Determinant, Designated L3T4a, Recognized by Monoclonal Antibody GK 1.5: Expression of L3T4a by Functional T Cell Clones Appears to Correlate Primarily with Class II MHC Antigen‐Reactivity

1983 • 1,040 citations

Monoclonal antibodies to the p21 products of the transforming gene of Harvey murine sarcoma virus and of the cellular ras gene family

1982 • 836 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

The SCID Mouse Mutant: Definition, Characterization, and Potential Uses

1991 • 743 citations

Developmental Biology of T Cells in T Cell-Receptor Transgenic Mice

1990 • 637 citations

A monoclonal antibody discriminating between subsets of T and B cells.

1981 • 565 citations

B220: a B cell-specific member of the T200 glycoprotein family

1981 • 525 citations

Developmental regulation of T-cell receptor gene expression

1985 • 522 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Molecular and Cellular Events of T Cell Development

1989 • 466 citations

V(D)J Recombination: Molecular Biology and Regulation

1992 • 464 citations

Co-association of CD3ζ with a receptor (CD16) for IgG Fc on human natural killer cells

1989 • 412 citations

Restoration of T Cell Development in RAG-2-Deficient Mice by Functional TCR Transgenes

1993 • 403 citations

Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice

1991 • 368 citations

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

1983 • 348 citations

CD4 expressed on earliest T-lineage precursor cells in the adult murine thymus

1991 • 343 citations

VDJ recombination

1992 • 307 citations

TISSUE INTERACTION IN THE DEVELOPMENT OF THYMUS LYMPHOCYTES

1969 • 295 citations

Developmental potential of the earliest precursor cells from the adult mouse thymus.

1991 • 294 citations

Expression of T-cell antigen receptor genes during fetal development in the thymus

1985 • 293 citations

A macrophage Fcγ receptor and the mast cell receptor for IgE share an identical subunit

1989 • 268 citations

A population of early fetal thymocytes expressing FcγRIIIII contains precursors of T lymphocytes and natural killer cells

1992 • 264 citations

Monoclonal antibodies specific to native murine T-cell receptor gamma delta: analysis of gamma delta T cells during thymic ontogeny and in peripheral lymphoid organs.

1989 • 257 citations

Early Events in T-Cell Maturation

1987 • 242 citations

CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation.

1992 • 220 citations

Expression and functional significance of the J11d marker on mouse thymocytes.

1987 • 218 citations

Developmental Status and Reconstitution Potential of Subpopulations of Murine Thymocytes

1988 • 211 citations

Studies of thymocytopoiesis in rats and mice. I. Kinetics of appearance of thymocytes using a direct intrathymic adoptive transfer assay for thymocyte precursors.

1986 • 188 citations

A murine early thymocyte developmental sequence is marked by transient expression of the interleukin 2 receptor.

1989 • 185 citations

Fc gamma receptor type III (CD16) is included in the zeta NK receptor complex expressed by human natural killer cells.

1990 • 169 citations

Differentiation potential of subsets of CD4−8− thymocytes

1987 • 169 citations

Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.

1989 • 159 citations

Phenotypic and functional stages in the intrathymic development of αβ T cells

1991 • 151 citations

Lineage relationships and developmental kinetics of immature thymocytes: CD3, CD4, and CD8 acquisition in vivo and in vitro.

1990 • 143 citations

T cell receptor (TCR) beta chain homodimers on the surface of immature but not mature alpha, gamma, delta chain deficient T cell lines.

1992 • 137 citations

Intrathymic maturation of murine T lymphocytes from CD8+ precursors.

1989 • 134 citations

IgG anti-DNA autoantibodies within an individual autoimmune mouse are the products of clonal selection.

1989 • 131 citations

Monoclonal antibodies specific for murine CD2 reveal its presence on B as well as T cells.

1989 • 118 citations

Seeding of the 10-day mouse embryo thymic rudiment by lymphocyte precursors in vitro.

1981 • 109 citations

Two rare populations of mouse Thy-1lo bone marrow cells repopulate the thymus.

1988 • 98 citations

CD3 zeta dependence of the CD2 pathway of activation in T lymphocytes and natural killer cells.

1992 • 88 citations

A molecular basis for thymic selection: regulation of T11 induced thymocyte expansion by the T3-Ti antigen/MHC receptor pathway

1985 • 84 citations

Thymocytes expressing CD8 differentiate into CD4+ cells following intrathymic injection.

1988 • 72 citations

Thymocyte subpopulation enriched for progenitors with an unrearranged T-cell receptor β-chain gene

1985 • 72 citations

Subpopulations of early thymocytes. A cross-correlation flow cytometric analysis of adult mouse Ly-2-L3T4-(CD8-CD4-) thymocytes using eight different surface markers.

1988 • 63 citations

Heterogeneity of immature (Lyt-2-/L3T4-) thymocytes. Identification of four major phenotypically distinct subsets differing in cell cycle status and in vitro activation requirements.

1988 • 57 citations

Expression and ontogeny of CD2 on murine B cells.

1990 • 44 citations

Negative selection of thymocytes. A novel polymerase chain reaction-based molecular analysis detects requirements for macromolecular synthesis.

1992 • 42 citations

Expression and function of CD2 during murine thymocyt

1989 • 36 citations

Expression and ontogeny of murine CD2

1989 • 29 citations

CD2 expression in murine B cell lineage

1989 • 23 citations

Murine epidermal γ/δ T cells express Fcγ receptor II encoded by the FcγRα α gene

1991 • 22 citations

Quantitative analysis of Fc gamma receptors on murine spleen cell populations by using dual parameter flow cytometry.

1984 • 22 citations

Ontogeny and distribution of the murine B cell Fc gamma RII.

1992 • 20 citations