CLASS II ANTIGENS AND DISEASE SUSCEPTIBILITY

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

The shared epitope hypothesis. an approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis

1987 • 2,539 citations

Type I Diabetes Mellitus

1986 • 1,615 citations

HLA and Disease Associations

1985 • 893 citations

The Influence of HLA-DRB1 Genes on Disease Severity in Rheumatoid Arthritis

1992 • 520 citations

Evidence of significant radiographic damage in rheumatoid arthritis within the first 2 years of disease.

1989 • 346 citations

HLA Genes associated with rheumatoid Arthritis. Identification of susceptibility alleles using specific oligonucleotide probes

1989 • 345 citations

Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus.

1992 • 290 citations

Identification of susceptibility loci for insulin-dependent diabetes mellitus by trans-racial gene mapping

1989 • 238 citations

POPULATION GENETICS OF RHEUMATOID ARTHRITIS

1992 • 195 citations

A Unified Hypothesis for the Complex Genetics of HLA Associations With IDDM

1990 • 190 citations

Association of HLA–DR4 with a more progressive disease course in patients with rheumatoid arthritis. Results of a followup study

1991 • 163 citations

Transcomplementation of HLA Genes in IDDM: HLA-DQ α and β-Chains Produce Hybrid Molecules in DR3/4 Heterozygotes

1987 • 158 citations

Association of HLA–Dw16 with rheumatoid arthritis in Yakima Indians. Further evidence for the “shared epitope” hypothesis

1991 • 157 citations

Life-Table Analysis of Progression to Diabetes of Anti-Insulin Autoantibody-Positive Relatives of Individuals With Type I Diabetes

1989 • 141 citations

FAMILIAL PATTERNS OF NARCOLEPSY

1989 • 137 citations

Can We Really Predict IDDM?

1993 • 129 citations

Strong association of insulin autoimmune syndrome with HLA-DR4

1992 • 120 citations

HLA-DR2 and Dw2 in Narcolepsy and in Other Disorders of Excessive Somnolence Without Cataplexy

1986 • 110 citations

HLA-DQ allelic polymorphisms constrain patterns of class II heterodimer formation.

1993 • 110 citations

PREDICTION OF SUSCEPTIBILITY TO RHEUMATOID ARTHRITIS BY HUMAN LEUKOCYTE ANTIGEN GENOTYPING

1992 • 94 citations

Destructive arthritis, rheumatoid factor, and HLA–DR4. Susceptibility versus severity, a case–control study

1989 • 89 citations

A unified hypothesis for the complex genetics of HLA associations with IDDM

1990 • 74 citations

Structural requirements for recognition of the HLA-Dw14 class II epitope: a key HLA determinant associated with rheumatoid arthritis.

1990 • 61 citations

Life-table analysis of progression to diabetes of anti-insulin autoantibody-positive relatives of individuals with type I diabetes

1989 • 61 citations

Prediction and Prevention of IDDM—1991

1991 • 59 citations

Polymorphic DQ alpha and DQ beta interactions dictate HLA class II determinants of allo-recognition.

1990 • 54 citations

Immunogenetic heterogeneity of rheumatoid arthritis.

1986 • 53 citations

Immunogenetics and IDDM

1994 • 52 citations

How, When, and Why to Predict IDDM

1988 • 50 citations

Transcomplementation of HLA genes in IDDM. HLA-DQ alpha- and beta-chains produce hybrid molecules in DR3/4 heterozygotes

1987 • 45 citations

Can we really predict IDDM?

1993 • 38 citations

High Genetic Risk for IDDM in the Pacific Northwest: First Report From the Washington State Diabetes Prediction Study

1994 • 36 citations

Selective immunosuppression

1993 • 30 citations

Prediction and prevention of IDDM--1991

1991 • 26 citations

Erosive rheumatoid factor negative and positive rheumatoid arthritis are immunogenetically similar.

1994 • 22 citations

How, when, and why to predict IDDM

1988 • 16 citations

High genetic risk for IDDM in the Pacific Northwest. First report from the Washington State Diabetes Prediction Study

1994 • 15 citations

Factors Governing the Binding and Recognition of Foreign and Self-Peptides by Mhc Class II

1993 • 3 citations

PREFACE

1992 • 2 citations

Mutagenesis and Expression of Putative Class II Susceptibility Genes: a “Reverse Immunogenetics” Approach to Analysis of HLA and Disease

1990 • 2 citations