The pineal gland and reproduction

The melatonin rhythm: both a clock and a calendar

1993 • 985 citations

The Pineal Gland: A Neurochemical Transducer

1974 • 872 citations

Melatonin: A Coordinating Signal for Mammalian Reproduction?

1985 • 631 citations

Neuroendocrine Basis of Seasonal Reproduction

1984 • 603 citations

The timed infusion paradigm for melatonin delivery: What has it taught us about the melatonin signal, its reception, and the photoperiodic control of seasonal responses?

1993 • 525 citations

The immunoneuroendocrine role of melatonin

1993 • 493 citations

Activation of protein kinase C potentiates isoprenaline-induced cyclic AMP accumulation in rat pinealocytes

1985 • 415 citations

Alterations in Nocturnal Serum Melatonin Levels In Humans With Growth and Aging*

1988 • 401 citations

Photoneural Regulation of the Mammalian Pineal Gland

1985 • 367 citations

The influence of photoperiod and melatonin on testis size, body weight, and pelage colour in the Djungarian hamster (Phodopus sungorus)

1973 • 323 citations

FALL IN NOCTURNAL SERUM MELATONIN DURING PREPUBERTY AND PUBESCENCE

1984 • 309 citations

Atypical Synergisticα₁- andβ-Adrenergic Regulation of Adenosine 3′,5′-Monophosphate and Guanosine 3′,5′- Monophosphate in Rat Pinealocytes

1985 • 256 citations

Melatonin and melatonin-progestin combinations alter pituitary-ovarian function in women and can inhibit ovulation.

1992 • 218 citations

Inverse Seasonal Relationship Between Melatonin and Ovarian Activity in Humans in a Region With a Strong Seasonal Contrast in Luminosity*

1987 • 207 citations

Seasonality in human reproduction: an update

1992 • 205 citations

Serotonin function in panic disorder: a double blind placebo controlled study with fluvoxamine and ritanserin

1990 • 194 citations

Melatonin receptors in human hypothalamus and pituitary: implications for circadian and reproductive responses to melatonin.

1993 • 188 citations

AMPLIFICATION OF NOCTURNAL MELATONIN SECRETION IN WOMEN WITH FUNCTIONAL HYPOTHALAMIC AMENORRHEA

1988 • 184 citations

Morning vs Evening Light Treatment for Winter Depression

1990 • 181 citations

The Circadian Rhythm of Plasma Melatonin During the Normal Menstrual Cycle and in Amenorrheic Women*

1988 • 179 citations

Circadian and Seasonal Variation in Human Preovulatory Follicular Fluid Melatonin Concentration*

1990 • 168 citations

Improving Adaptation to Simulated Night Shift: Timed Exposure to Bright Light Versus Daytime Melatonin Administration

1995 • 166 citations

Evidence for a cytoplasmic melatonin receptor

1978 • 153 citations

Pineal Melatonin Mediates Photoperiodic Control of Pulsatile Luteinizing Hormone Secretion in the Ewe

1985 • 151 citations

Photoperiod, Pineal, Melatonin and Reproduction in Hamsters

1979 • 150 citations

Central melatonin receptors: Implications for a mode of action

1989 • 142 citations

Photoperiodic Synchronization of a Circannual Reproductive Rhythm in Sheep: Identification of Season-Specific Time Cues1

1994 • 140 citations

Differences in the Quality of Semen in Outdoor Workers during Summer and Winter

1990 • 137 citations

Altered Waveform of Plasma Nocturnal Melatonin Secretion in Premenstrual Depression

1990 • 128 citations

Serum Melatonin in Central Precocious Puberty Is Lower than in Age-Matched Prepubertal Children*

1991 • 125 citations

Short-Day Effects of Melatonin on Luteinizing Hormone Secretion in the Ewe: Evidence for Central Sites of Action in the Mediobasal Hypothalamus1

1993 • 125 citations

Function of melatonin in thermoregulatory processes

1994 • 120 citations

Circadian Rhythms in Serum Melatonin from Infancy to Adolescence

1985 • 109 citations

Melatonin receptors in human hypothalamus and pituitary: implications for circadian and reproductive responses to melatonin

1993 • 96 citations

Seasonal, menstrual and circadian secretions of melatonin, gonadotropins and prolactin in women

1988 • 95 citations

Central sites mediating reproductive responses to melatonin in juvenile male Siberian hamsters

1992 • 90 citations

The metabolic fate of infusedl-tryptophan in men: possible clinical implications of the accumulation of circulating tryptophan and tryptophan metabolites

1992 • 88 citations

Regulation of Luteinizing Hormone-Releasing Hormone (LHRH) Secretion by Melatonin in the Ewe.I. Simultaneous Delayed Increase in LHRH and Luteinizing Hormone Pulsatile Secretion1

1995 • 84 citations

Melatonin and melatonin-progestin combinations alter pituitary-ovarian function in women and can inhibit ovulation

1992 • 82 citations

Inhibition of Ovulation by Melatonin in the Cyclic Rat1

1973 • 79 citations

Melatonin inhibits gonadotropin-releasing hormone-induced elevation of intracellular Ca2+ in neonatal rat pituitary cells.

1992 • 78 citations

Neural pathways and neurotransmitters affecting melatonin synthesis.

1986 • 77 citations

Synchronization of the Circannual Reproductive Rhythm of the Ewe by Discrete Photoperiodic Signals1

1991 • 77 citations

Circadian Pattern of Plasma Melatonin Concentrations during Four Phases of the Human Menstrual Cycle

1990 • 76 citations

The pineal gland: An intermediary between the environment and the endocrine system

1983 • 76 citations

Marked Augmentation of Nocturnal Melatonin Secretion in Amenorrheic Athletes, but not in Cycling Athletes: Unaltered by Opioidergic or Dopaminergic Blockade*

1991 • 75 citations

Effects of long-term administration of melatonin and a putative antagonist on the ageing rat

1995 • 74 citations

Acute phase-shifting effects of melatonin associated with suppression of core body temperature in humans

1994 • 72 citations

Delayed Puberty in the Male Djungarian Hamster: Effect of Short Photoperiod or Melatonin Treatment on the GnRH Neuronal System

1991 • 70 citations

Melatonin and human puberty: Current perspectives

1993 • 70 citations

Influence of Photoperiod on Pineal Melatonin Synthesis, Fur Color, Body Weight, and Reproductive Function in the Female Djungarian Hamster, Phodopus sungorus

1993 • 69 citations

Neuroendocrine effects of light

1991 • 68 citations

Plasma Melatonin Rhythm in Normal Puberty: Interactions of Age and Pubertal Stages

1992 • 67 citations

Seasonal Influence of Diurnal Rhythms in the Onset of the Plasma Luteinizing Hormone Surge in Women

1982 • 66 citations

The Effect of Melatonin on Steroidogenesis by the Human Ovaryin Vitro

1975 • 63 citations

Seasonal Distribution of Births in Australia

1983 • 62 citations

Delayed Sexual Maturation Induced by Daily Melatonin Administration Eliminates the LH Response to Naloxone despite Normal Responsiveness to GnRH in Juvenile Male Rats

1988 • 62 citations

Alterations to Plasma Melatonin and Cortisol After Evening Alprazolam Administration in Humans

1993 • 59 citations

Melatonin and the human gonadotrophin-releasing hormone pulse generator

1991 • 58 citations

Constant Pineal Output and Increasing Body Mass Account for Declining Melatonin Levels During Human Growth and Sexual Maturation

1988 • 58 citations

Effects of melatonin on progesterone production by human granulosa lutein cells in culture

1992 • 54 citations

Mediation of the short-loop negative feedback of luteinizing hormone (LH) on LH-releasing hormone release by melatonin-induced inhibition of LH release from the pars tuberalis.

1991 • 53 citations

2-[<sup>125</sup>I]Iodomelatonin Binding Sites in the Testis and Ovary: Putative Melatonin Receptors in the Gonads

1994 • 52 citations

Melatonin: a contraceptive for the nineties

1993 • 50 citations

The influences of illumination, melatonin and pinealectomy on testicular function in the rat

1971 • 48 citations

Social cues can play a role in timing onset of the breeding season of the ewe

1989 • 47 citations

Infertility: Seasonality in the results of in-vitro fertilization

1994 • 46 citations

Parameters of the circadian rhythm of pineal melatonin secretion affecting reproductive responses in Siberian hamsters

1991 • 46 citations

Photoperiodic requirements for timing onset and duration of the breeding season of the ewe: Synchronization of an endogenous rhythm of reproduction

1990 • 46 citations

Structures and molecules involved in generation and regulation of biological rhythms in vertebrates and invertebrates

1993 • 45 citations

Melatonin inhibits gonadotropin-releasing hormone-induced elevation of intracellular Ca2+ in neonatal rat pituitary cells

1992 • 43 citations

Enhanced circadian rhythm of melatonin in anorexia nervosa

1989 • 42 citations

RAPID COMMUNICATION: SERUM IMMUNOREACTIVE MELATONIN IN BOYS WITH DELAYED PUBERTY

1982 • 42 citations

Radioimmunoassayable Melatonin: Circulating Patterns in Man and Sheep

1979 • 41 citations

Angular-linear correlation coefficient for rhythmometry and circannually changing human birth rates at different geographic latitudes.

1973 • 40 citations

Melatonin Inhibition of the <i>in vivo</i> Pituitary Response to Luteinizing Hormone-Releasing Hormone in the Neonatal Rat

1980 • 40 citations

Seasonal Variations in the Onset of Puberty in Rats1

1972 • 38 citations

Melatonin Does Not Suppress the Pituitary Luteinizing Hormone Response to Luteinizing Hormone-Releasing Hormone in Men*

1980 • 38 citations

Sex steroids do not alter melatonin secretion in the human

1994 • 38 citations

Diurnal modulation of rat hypothalamic gonadotropin-releasing hormone release by melatonin in vitro

1993 • 37 citations

Reliable analysis of individual human megaton profiles by complex cosinor analysis

1994 • 37 citations

EFFECT OF PHOTIC STIMULATION ON THE HUMAN MENSTRUAL CYCLE

1978 • 36 citations

Melatonin Entrains the Circadian Rhythm in the Rat Pineal N-Acetyltransferase Activity

1990 • 36 citations

Seasonality and Melatonin Receptors in the Pars tuberalis in Some Long Day Breeders

1994 • 35 citations

The Pineal and Pubertal Development

1985 • 32 citations

The Pineal Gland

1988 • 31 citations

Seasonal regulation of melatonin receptors in rodent pars tuberalis: correlation with reproductive state

1994 • 30 citations

The effect of season on circulating concentrations of anterior pituitary, ovarian and adrenal cortex hormones and hormone binding proteins in the subarctic area; evidence of increased activity of the pituitary-ovarian axis in spring

1987 • 30 citations

Physiology of puberty.

1989 • 29 citations

What does changing the temperature do to the melatonin rhythm in cultured chick pineal cells?

1994 • 27 citations

Nocturnal melatonin levels are unaltered by ovarian suppression in girls with central precocious puberty

1989 • 27 citations

Melatonin and photoperiodic time measurement: Seasonal breeding in the sheep

1993 • 25 citations

The 5-Methoxyindoles Different from Melatonin: Their Effects on the Sexual Axis

1983 • 22 citations

Seasonal Changes in Obstetrical Phenomena¹

1965 • 22 citations

Serum prolactin and luteinizing hormone levels and the activities of hypothalamic monoamine oxidase A and B and phenylethanolamine‐N‐methyl transferase are changed during sexual maturation in male rats treated neonatally with melatonin

1992 • 22 citations

Seasonal Variation in Human Semen Quality

1991 • 19 citations

Effects of Pinealectomy and Melatonin on the Timing of the Proestrous Luteinizing Hormone Surge in the Rat

1994 • 18 citations

Effects of Melatonin Agonists and Antagonists on Reproduction and Body Weight in the Siberian Hamster

1990 • 18 citations

The amplitude of nocturnal melatonin concentrations is not decreased by oestradiol and does not alter reproductive function in adolescent or adult female rhesus monkeys

1993 • 17 citations

Interruption of nocturnal pineal melatonin synthesis in spontaneous recrudescent Djungarian hamsters (Phodopus sungorus)

1992 • 16 citations

Melatonin disturbances in anorexia nervosa and bulimia nervosa

1994 • 16 citations

Melatonin inhibits luteinizing hormone releasing hormone (LHRH) induction of LH release from fetal rat pituitary cells

1995 • 15 citations

Regulation of Melatonin Synthesis in the Ovine Pineal Gland

1991 • 14 citations

Exogenous melatonin enhances the TRH-induced prolactin release in normally cycling women: A sex-specific effect

1991 • 11 citations

Bedeutung der Zirbeldrüse bei Reproduktion und gynäkologischen Tumoren

1991 • 10 citations

Synchronization of the circannual reproductive rhythm of the ewe by discrete photoperiodic signals

1991 • 8 citations

[Present and future of melatonin in human and animal reproduction functions].

1993 • 6 citations

Melatonin directly stimulates the secretion of progesterone by human granulosa cells

1985 • 5 citations

Differences in the Quality of Semen in Outdoor Workers during Summer and Winter

1990 • 5 citations

Inhibin‐like “antigonadotropic” activity in the ovine pineal

1992 • 4 citations

[Influence of the maternal pineal gland on the testicular function in rats].

1992 • 4 citations

Nocturnal melatonin levels are unaltered by ovarian suppression in girls with central precocious puberty

1990 • 4 citations

[Seasonal affective disorders, a new clinical category].

1990 • 2 citations

SEASONAL CHANGES IN OBSTETRICAL PHENOMENA

1966 • 1 citations

Deleted Work

1955 • 0 citations