Aurintricarboxylic acid prevents GLUR2 mRNA down-regulation and delayed neurodegeneration in hippocampal CA1 neurons of gerbil after global ischemia

Delayed neuronal death in the gerbil hippocampus following ischemia

1982 • 2,856 citations

Temporal profile of neuronal damage in a model of transient forebrain ischemia

1982 • 2,695 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

A Family of AMPA-Selective Glutamate Receptors

1990 • 1,453 citations

Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS

1990 • 1,234 citations

2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a Neuroprotectant for Cerebral Ischemia

1990 • 1,125 citations

The Role of Zinc in Selective Neuronal Death After Transient Global Cerebral Ischemia

1996 • 1,057 citations

Calcium: still center-stage in hypoxic-ischemic neuronal death

1995 • 921 citations

Selective vulnerability of the hippocampus in brain ischemia

1991 • 876 citations

Delayed neuronal death in the CA1 pyramidal cell layer of the gerbil hippocampus following transient ischemia is apoptosis

1995 • 834 citations

Ischemia-induced neuronal apoptosis

1996 • 600 citations

Essential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.

1995 • 558 citations

The GluR2 (GluR-B) hypothesis: Ca2+-permeable AMPA receptors in neurological disorders

1997 • 538 citations

Neural apoptosis

1995 • 464 citations

AMPA and kainate receptors

1995 • 460 citations

Switch in glutamate receptor subunit gene expression in CA1 subfield of hippocampus following global ischemia in rats.

1992 • 399 citations

Calcium Accumulation and Neuronal Damage in the Rat Hippocampus following Cerebral Ischemia

1987 • 374 citations

Aurintricarboxylic acid rescues PC12 cells and sympathetic neurons from cell death caused by nerve growth factor deprivation: correlation with suppression of endonuclease activity.

1991 • 359 citations

Early Detection of DNA Strand Breaks in the Brain After Transient Focal Ischemia: Implications for the Role of DNA Damage in Apoptosis and Neuronal Cell Death

1997 • 312 citations

Global Ischemia Induces Downregulation of Glur2 mRNA and Increases AMPA Receptor-Mediated Ca²⁺Influx in Hippocampal CA1 Neurons of Gerbil

1997 • 295 citations

Use of aurintricarboxylic acid as an inhibitor of nucleases during nucleic acid isolation

1977 • 280 citations

Kainate-induced status epilepticus alters glutamate and GABAA receptor gene expression in adult rat hippocampus: an in situ hybridization study

1994 • 271 citations

Mechanisms of secondary brain injury.

1996 • 261 citations

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

1991 • 253 citations

Differential expression of three glutamate receptor genes in developing rat brain: an in situ hybridization study.

1991 • 252 citations

A single amino acid determines the subunit-specific spider toxin block of alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor channels.

1993 • 243 citations

The N-methyl-D-aspartate antagonist, MK-801, fails to protect against neuronal damage caused by transient, severe forebrain ischemia in adult rats

1991 • 239 citations

Ion Homeostasis in Rat Brain in vivo: Intra- and Extracellular [Ca²⁺] and [H⁺] in the Hippocampus during Recovery from Short-Term, Transient Ischemia

1992 • 234 citations

Nerve growth factor withdrawal-induced cell death in neuronal PC12 cells resembles that in sympathetic neurons.

1992 • 221 citations

The non-NMDA antagonists, NBQX and GYKI 52466, protect against cortical and striatal cell loss following transient global ischaemia in the rat

1992 • 201 citations

Mechanisms of secondary brain injury

1996 • 197 citations

Distribution of glutamate receptor subtypes in the vertebrate retina

1995 • 197 citations

Alterations of the GluR-B AMPA receptor subunit flip/flop expression in kainate-induced epilepsy and ischemia

1993 • 196 citations

Argiotoxin detects molecular differences in AMPA receptor channels

1993 • 186 citations

K+ channel openers prevent global ischemia-induced expression of c-fos, c-jun, heat shock protein, and amyloid beta-protein precursor genes and neuronal death in rat hippocampus.

1993 • 183 citations

Delayed c-fos proto-oncogene expression in the rat hippocampus induced by transient global cerebral ischemia: an in situ hybridization study

1989 • 178 citations

DNA Fragmentation Follows Delayed Neuronal Death in CA1 Neurons Exposed to Transient Global Ischemia in the Rat

1997 • 146 citations

Expression of glutamate receptor genes in the mammalian retina: the localization of GluR1 through GluR7 mRNAs

1993 • 144 citations

Mechanism of action of polymeric aurintricarboxylic acid, a potent inhibitor of protein-nucleic acid interactions

1980 • 138 citations

Global ischemia induces apoptosis-associated genes in hippocampus

1996 • 133 citations

Differences in DNA Fragmentation following Transient Cerebral or Decapitation Ischemia in Rats

1995 • 116 citations

Protection against ischemic hippocampal CAI damage in the rat with a new non-NMDA antagonist, NBQX

1992 • 108 citations

NMDA and Non‐NMDA Receptor Gene Expression Following Global Brain Ischemia in Rats: Effect of NMDA and Non‐NMDA Receptor Antagonists

1994 • 91 citations

Aurintricarboxylic Acid Protects Hippocampal Neurons from NMDA‐and Ischemia‐Induced Toxicity In Vivo

1993 • 89 citations

REVIEW ■ : Neuroprotection in Brain Ischemia: An Update (Part I

1995 • 77 citations

Biphasic Expression of the Fos and Jun Families of Transcription Factors Following Transient Forebrain Ischaemia in the Rat. Effect of Hypothermia

1995 • 77 citations

The GluR2 hypothesis: Ca(++)-permeable AMPA receptors in delayed neurodegeneration.

1996 • 74 citations

Retinal ischemia leads to apoptosis which is ameliorated by aurintricarboxylic acid

1997 • 73 citations

Effects of a spider toxin and its analogue on glutamate-activated currents in the hippocampal CA1 neuron after ischemia

1995 • 72 citations

Sublethal Oxygen–Glucose Deprivation Alters Hippocampal Neuronal AMPA Receptor Expression and Vulnerability to Kainate-Induced Death

1997 • 68 citations

Effect of ischaemia and reperfusion on the extra- and intracellular distribution of glutamate, glutamine, aspartate and GABA in the rat hippocampus, with a note on the effect of the sodium channel blocker BW1003C87

1993 • 68 citations

Untitled

1996 • 63 citations

The Prognosis and Treatment of Headaches in Children – a Ten Year Follow-up

1995 • 62 citations

Inhibition of RNA-directed DNA polymerase by aurintricarboxylic acid.

1976 • 50 citations

Electrophysiological changes of CA1 pyramidal neurons following transient forebrain ischemia: an in vivo intracellular recording and staining study

1996 • 47 citations

Aurintricarboxylic Acid Prevents NMDA‐Mediated Excitotoxicity: Evidence for Its Action as an NMDA Receptor Antagonist

1993 • 46 citations

Short‐term and Long‐term Changes in the Postischemic Hippocampus

1994 • 41 citations

Aurintricarboxylic Acid, a Preferential Inhibitor of Initiation of Protein Synthesis

1971 • 34 citations

Pretreatment with intraventricular aurintricarboxylic acid decreases infarct size by inhibiting apoptosis following transient global ischemia in gerbils

1998 • 29 citations

Deep Prepiriform Cortex Modulates Neuronal Cell Death in Global Ischemia

1997 • 8 citations

Pharmacologic blockade of non-NMDA receptors at deep prepiriform cortex attenuates heat shock protein expression in global ischemia

1997 • 5 citations