Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma.

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Intratumor microvessel density as a prognostic factor in cancer.

1995 • 881 citations

Relation of neovascularisation to metastasis of non-small-cell lung cancer

1992 • 780 citations

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

1995 • 766 citations

Detection of p53 Gene Mutations in Human Brain Tumors by Single-strand Conformation Polymorphism Analysis of Polymerase Chain Reaction Products

1991 • 556 citations

The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study.

1988 • 538 citations

Incidence and possible clinical significance of K-ras oncogene activation in adenocarcinoma of the human lung.

1988 • 458 citations

Clinical importance of the determination of tumor angiogenesis in breast carcinoma: much more than a new prognostic tool.

1995 • 441 citations

Clinical significance of ras oncogene activation in human lung cancer

1993 • 361 citations

Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines

1992 • 298 citations

Induction of Vascular Endothelial Growth Factor by Insulin-like Growth Factor 1 in Colorectal Carcinoma

1996 • 272 citations

Growth of cell lines and clinical specimens of human non-small cell lung cancer in a serum-free defined medium

1987 • 263 citations

ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.

1991 • 249 citations

K-ras oncogene activation in atypical alveolar hyperplasias of the human lung.

1996 • 216 citations

ras gene mutations as a prognostic marker in adenocarcinoma of the human lung without lymph node metastasis.

1992 • 168 citations

Detection of K-ras mutations in lung carcinomas: Relationship to prognosis

1996 • 166 citations

Increased prevalence of K-ras oncogene mutations in lung adenocarcinoma

1995 • 157 citations

Prognostic impact of mutated K-ras gene in surgically resected non-small cell lung cancer patients

1994 • 156 citations

Platelet-derived endothelial cell growth factor expression correlates with tumour angiogenesis and prognosis in non-small-cell lung cancer

1997 • 140 citations

New Prognostic Factors in Lung Cancer

1995 • 95 citations

Association of point mutation in c-Ki-ras oncogene in lung adenocarcinoma with particular reference to cytologic subtypes

1990 • 86 citations

Prognostic significance of image morphometric microvessel enumeration in breast carcinoma.

1993 • 81 citations

What, if anything, is an angiogenic factor?

1996 • 70 citations

Autocrine Growth Loop of The Epidermal Growth Factor Receptor in Normal and Immortalized Human Bronchial Epithelial Cells

1996 • 53 citations

Mutations of K-ras oncogene and absence of H-ras mutations in squamous cell carcinomas of the lung

1995 • 37 citations

Proto-oncogene and growth factor/receptor expression in the establishment of primary human non-small cell lung carcinoma cell lines.

1993 • 35 citations

Recurrence and death in non-small cell lung carcinomas: a prognostic model using pathological parameters, microvessel count, and gene protein products.

1996 • 30 citations

A Universal Method for the Mutational Analysis of K-ras and p53 Gene in Non-small-cell Lung Cancer Using Formalin-Fixed Paraffin-Embedded Tissue

1995 • 27 citations

Annulate Lamellae in a Large Cell Lung Carcinoma Cell Line with High Expression of Tyrosine Kinase Receptor and Proto-Oncogenes

1992 • 16 citations