Rat α3/β4 Subtype of Neuronal Nicotinic Acetylcholine Receptor Stably Expressed in a Transfected Cell Line: Pharmacology of Ligand Binding and Function

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1973 • 12,522 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Molecular cloning, functional properties, and distribution of rat brain alpha 7: a nicotinic cation channel highly permeable to calcium

1993 • 1,455 citations

Distribution of alpha2, alpha3, alpha4, and beta2 neuronal nicotinic receptor subunit mRNAs in the central nervous system: A hybridization histochemical study in the rat

1989 • 1,049 citations

A subtype of nicotinic cholinergic receptor in rat brain is composed of alpha 4 and beta 2 subunits and is up-regulated by chronic nicotine treatment.

1992 • 858 citations

Both alpha- and beta-subunits contribute to the agonist sensitivity of neuronal nicotinic acetylcholine receptors

1991 • 552 citations

Brain α-bungarotoxin binding protein cDNAs and MAbs reveal subtypes of this branch of the ligand-gated ion channel gene superfamily

1990 • 471 citations

Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family.

1987 • 431 citations

Properties of neuronal nicotinic acetylcholine receptors: pharmacological characterization and modulation of synaptic function.

1997 • 431 citations

Epibatidine, a potent analgetic and nicotinic agonist.

1994 • 371 citations

Endocytosis and recycling of G protein-coupled receptors

1997 • 342 citations

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes

1993 • 303 citations

Studies on the mechanism of action of acetylcholine antagonists on rat parasympathetic ganglion cells.

1979 • 295 citations

The functional diversity of the neuronal nicotinic acetylcholine receptors is increased by a novel subunit: β4

1989 • 294 citations

Neurons Can Maintain Multiple Classes of Nicotinic Acetylcholine Receptors Distinguished by Different Subunit Compositions

1995 • 293 citations

Release of [³H]‐noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [³H]‐dopamine release

1996 • 263 citations

Partial agonist properties of cytisine on neuronal nicotinic receptors containing the beta 2 subunit.

1994 • 255 citations

Alpha-conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes.

1997 • 210 citations

The α5 gene product assembles with multiple acetylcholine receptor subunits to form distinctive receptor subtypes in brain

1992 • 205 citations

Structural and pharmacological characterization of the major brain nicotinic acetylcholine receptor subtype stably expressed in mouse fibroblasts.

1991 • 196 citations

Characterization of (+/-)(-)[3H]epibatidine binding to nicotinic cholinergic receptors in rat and human brain.

1995 • 194 citations

Existence of different subtypes of nicotinic acetylcholine receptors in the rat habenulo-interpeduncular system

1991 • 193 citations

Alpha 5, alpha 3, and non-alpha 3. Three clustered avian genes encoding neuronal nicotinic acetylcholine receptor-related subunits.

1990 • 191 citations

α-Conotoxin MII Blocks Nicotine-Stimulated Dopamine Release in Rat Striatal Synaptosomes

1997 • 189 citations

Neuronal Nicotinic Receptor Expression in Sensory Neurons of the Rat Trigeminal Ganglion: Demonstration of α3β4, a Novel Subtype in the Mammalian Nervous System

1996 • 178 citations

The expression of nicotinic acetylcholine receptors by PC12 cells treated with NGF

1992 • 163 citations

Differential Regulation of Neuronal Nicotinic Receptor Binding Sites Following Chronic Nicotine Administration

1997 • 144 citations

Neuronal Nicotinic Acetylcholine Receptors on Bovine Chromaffin Cells: Cloning, Expression, and Genomic Organization of Receptor Subunits

1997 • 130 citations

Heterogeneity of Nicotinic Receptor Class and Subunit mRNA Expression among Individual Parasympathetic Neurons from Rat Intracardiac Ganglia

1997 • 122 citations

Comparison of neuronal nicotinic receptors in rat sympathetic neurones with subunit pairs expressed in Xenopus oocytes.

1994 • 105 citations

The developmental increase in ACh current densities on rat sympathetic neurons correlates with changes in nicotinic ACh receptor alpha-subunit gene expression and occurs independent of innervation

1994 • 103 citations

Expression and regulation of neuronal acetylcholine receptor mRNA in chick ciliary ganglia

1988 • 101 citations

[125I]IPH, an epibatidine analog, binds with high affinity to neuronal nicotinic cholinergic receptors.

1997 • 91 citations

Nicotinic acetylcholine receptor mRNA in dorsal root ganglion neurons

1991 • 89 citations

Pharmacological and physiological properties of a putative ganglionic nicotinic receptor, α3β4, expressed in transfected eucaryotic cells

1995 • 65 citations

An isotopic rubidium ion efflux assay for the functional characterization of nicotinic acetylcholine receptors on clonal cell lines

1988 • 48 citations

Heterogeneity of neuronal nicotinic acetylcholine receptors in thin slices of rat medial habenula.

1995 • 47 citations

Stable expression in HEK‐293 cells of the rat α3/β4 subtype of neuronal nicotinic acetylcholine receptor

1996 • 28 citations

Deleted Work

1955 • 0 citations

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