Hepatic mitochondrial glutathione depletion and progression of experimental alcoholic liver disease in rats

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: Applications to mammalian blood and other tissues

1969 • 6,007 citations

Determination of malonaldehyde precursor in tissues by thiobarbituric acid test

1978 • 4,931 citations

High-performance liquid chromatography analysis of nanomole levels of glutathione, glutathione disulfide, and related thiols and disulfides

1980 • 1,179 citations

Status of the mitochondrial pool of glutathione in the isolated hepatocyte.

1982 • 440 citations

High-affinity transport of glutathione is part of a multicomponent system essential for mitochondrial function.

1990 • 283 citations

Ethanol-induced liver fibrosis in rats fed high fat diet

1986 • 279 citations

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress.

1991 • 247 citations

Severe and progressive steatosis and focal necrosis in rat liver induced by continuous intragastric infusion of ethanol and low fat diet

1985 • 236 citations

Alcoholic Liver Disease: Pathologic, Pathogenetic and Clinical Aspects

1991 • 224 citations

Mitochondrial damage in muscle occurs after marked depletion of glutathione and is prevented by giving glutathione monoester.

1989 • 206 citations

Role of xanthine oxidase in ethanol-induced lipid peroxidation in rats

1990 • 188 citations

Insights into the pathogenesis of alcoholic liver necrosis and fibrosis: Status report

1990 • 180 citations

Depletion in vitro of mitochondrial glutathione in rat hepatocytes and enhancement of lipid peroxidation by adriamycin and 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)

1983 • 177 citations

THE EFFECTS OF CHRONIC ETHANOL CONSUMPTION ON HEPATIC MITOCHONDRIAL ENERGY METABOLISM

1990 • 170 citations

Glutathione metabolism in the lung: inhibition of its synthesis leads to lamellar body and mitochondrial defects.

1989 • 153 citations

Effect of chronic ethanol feeding on rat hepatocytic glutathione. Compartmentation, efflux, and response to incubation with ethanol.

1987 • 126 citations

Effects of chronic ethanol intoxication on oxidative phosphorylation in rat liver submitochondrial particles.

1979 • 118 citations

Effects of chronic ethanol feeding on rat hepatocytic glutathione. Relationship of cytosolic glutathione to efflux and mitochondrial sequestration.

1989 • 98 citations

Molecular alterations in the respiratory chain of rat liver after chronic ethanol consumption.

1981 • 96 citations

PURIFICATION AND ENZYMATIC IDENTITY OF MITOCHONDRIAL CONTRACTION-FACTORS I AND II

1962 • 86 citations

Mitochondrial glutathione status during Ca2+ ionophore-induced injury to isolated hepatocytes

1988 • 83 citations

Effects of chronic ethanol treatment upon rat liver mitochondria

1978 • 67 citations

The effect of ethanol on the temperature dependence of respiration and ATPase activities of rat liver mitochondria.

1980 • 66 citations

Hepatic adenine nucleotide metabolism measuredin vivo in rats fed ethanol and a high fat-low protein diet

1988 • 55 citations

Control of adenine nucleotide metabolism in hepatic mitochondria from rats with ethanol-induced fatty liver

1982 • 54 citations

Effect of chronic ethanol consumption on energy-linked processes associated with oxidative phosphorylation: Proton translocation and ATP-Pi exchange

1982 • 49 citations

Intracellular catalase function: Analysis of the catalatic activity by product formation in isolated liver cells

1982 • 39 citations

Comparison of Effects of Long‐Term Ethanol Consumption on the Heart and Liver of the Rat

1989 • 39 citations

In Vivohepatic energy metabolism during the progression of alcoholic liver disease: A noninvasive31p nuclear magnetic resonance study in rats

1990 • 38 citations

Assay, purification, properties and mechanism of action of γ-glutamylcysteine synthetase from the liver of the rat and Xenopus laevis

1973 • 38 citations

Nutrition and the origins of disease

1989 • 15 citations