Relationships between trait and state anxiety and the central benzodiazepine receptor: a PET study

Diagnostic and Statistical Manual of Mental Disorders

1988 • 12,705 citations

Co-planar stereotaxic atlas of the human brain

1989 • 7,557 citations

The Pharmacological Basis of Therapeutics

1986 • 2,365 citations

Rapid Automated Algorithm for Aligning and Reslicing PET Images

1992 • 1,958 citations

Benzodiazepine Receptor: Demonstration in the Central Nervous System

1977 • 1,705 citations

Benzodiazepine receptors in rat brain

1977 • 1,459 citations

A Stereotactic Method of Anatomical Localization for Positron Emission Tomography

1985 • 583 citations

The amygdala and emotion

1996 • 386 citations

IN-VIVO DEMONSTRATION OF REDUCED BENZODIAZEPINE RECEPTOR BINDING IN HUMAN EPILEPTIC FOCI

1988 • 361 citations

Decreased Brain GABAA-Benzodiazepine Receptor Binding in Panic Disorder

1998 • 355 citations

Compartmental Analysis of [¹¹C]Flumazenil Kinetics for the Estimation of Ligand Transport Rate and Receptor Distribution Using Positron Emission Tomography

1991 • 344 citations

CURRENT TRENDS IN THEORY AND RESEARCH ON ANXIETY

1972 • 325 citations

Flumazenil Provocation of Panic Attacks

1990 • 268 citations

Benzodiazepine Receptor Quantification in vivo in Humans Using [¹¹C]Flumazenil and PET: Application of the Steady-State Principle

1995 • 214 citations

Synthesis of ethyl 8-fluoro-5,6-dihydro5- [11C]methyl-6-oxo-4H-imidazo[1,5-a] [1,4]benzodiazepine-3-carboxylate (RO 15.1788-11C): A specific radioligand for the in vivo study of central benzodiazepine receptors by positron emission tomography

1984 • 186 citations

Neurobiological mechanisms in human anxiety evidence supporting central noradrenergic hyperactivity

1983 • 184 citations

ANXIETY STATES (ANXIETY NEUROSIS)

1973 • 179 citations

Differences in benzodiazepine receptor binding in maudsley reactive and maudsley non-reactive rats

1978 • 167 citations

Cerebral benzodiazepine receptor binding and distribution in generalized anxiety disorder: a fractal analysis

1997 • 162 citations

Reduced Benzodiazepine Sensitivity in Panic Disorder

1990 • 157 citations

Panic Attacks

1992 • 154 citations

Regional Specific Binding of [¹¹C]RO 15 1788 to Central Type Benzodiazepine Receptors in Human Brain: Quantitative Evaluation by PET

1988 • 118 citations

Reduced benzodiazepine receptor binding in panic disorders measured by iomazenil SPECT

1995 • 116 citations

Quantification of Benzodiazepine Receptors in Human Brain Using PET, [¹¹C]Flumazenil, and a Single-Experiment Protocol

1995 • 112 citations

Decreased benzodiazepine receptor binding in panic disorder measured by IOMAZENIL-SPECT

1994 • 100 citations

Benzodiazepine receptors in the brain as affected by different experimental stresses: The changes are small and not undirectional

1979 • 99 citations

A PET study of the functional neuroanatomy of writing impairment in Alzheimer's disease The role of the left supramarginal and left angular gyri

1995 • 94 citations

Central benzodiazepine receptors in human brain: estimation of regional Bmax and KD values with positron emission tomography

1992 • 93 citations

Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function.

1988 • 86 citations

Abnormal regional benzodiazepine receptor uptake in the prefrontal cortex in patients with panic disorder

1995 • 85 citations

Symptomatic volunteers in multicenter drug trials

1979 • 84 citations

Reduced benzodiazepine sensitivity in patients with panic disorder: comparison with patients with obsessive-compulsive disorder and normal subjects

1996 • 67 citations

Modeling Analysis of [¹¹C]Flumazenil Kinetics Studied by PET: Application to a Critical Study of the Equilibrium Approaches

1993 • 65 citations

New developments on the search for the endogenous ligand(s) of central benzodiazepine receptors

1988 • 48 citations

Increased urinary tribulin output in generalised anxiety disorder

1988 • 42 citations

Urinary Catecholamine Metabolite and Tribulin Output During Lactate Infusion

1988 • 42 citations

Social phobia and response to challenge procedures: Examining the interaction between anxiety sensitivity and trait anxiety

1994 • 29 citations

Saturation Analysis in PET—Analysis of Errors Due to Imperfect Reference Regions

1994 • 28 citations

Benzodiazepine‐GABA_A Receptor Binding During Absence Seizures

1995 • 28 citations

The relationship between benzodiazepine receptor sensitivity and neuroticism

1995 • 27 citations

Acute swim stress increases benzodiazepine receptors, but not GABAA or GABAB receptors, in the rat cerebral cortex

1993 • 24 citations

A comparison of methods for the separation of [11C]Ro 15-1788 (flumazenil) from its metabolites in the blood of rabbits, baboons and humans

1991 • 24 citations

The neuroanatomy of panic disorder: The emerging role of the right parahippocampal region

1992 • 18 citations

Investigation of the Dopamine System with Positron Emission Tomography: General Issues in Modelling

1991 • 8 citations