mRNA splicing efficiency in yeast and the contribution of nonconserved sequences

A catalogue of splice junction sequences

1982 • 3,861 citations

A new pair of M13 vectors for selecting either DNA strand of double-digest restriction fragments

1982 • 3,041 citations

pEMBL: a new family of single stranded plasmids

1983 • 1,231 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro

1984 • 761 citations

Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes

1983 • 627 citations

The U1 small nuclear RNA-protein complex selectively binds a 5′ splice site in vitro

1983 • 593 citations

Isolation and sequence of the gene for actin in Saccharomyces cerevisiae.

1980 • 567 citations

Lariat RNA's as Intermediates and Products in the Splicing of Messenger RNA precursors

1984 • 474 citations

Structure of a split yeast gene: complete nucleotide sequence of the actin gene in Saccharomyces cerevisiae.

1980 • 410 citations

The 5′ terminus of the RNA moiety of U1 small nuclear ribonucleoprotein particles is required for the splicing of messenger RNA precursors

1984 • 404 citations

Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts

1983 • 396 citations

Lariat structures are in vivo intermediates in yeast pre-mRNA splicing

1984 • 379 citations

Point mutations identify the conserved, intron-contained TACTAAC box as an essential splicing signal sequence in yeast

1984 • 339 citations

Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein

1983 • 333 citations

Abnormal RNA processing due to the exon mutation of βE-globin gene

1982 • 309 citations

A comparison of yeast ribosomal protein gene DNA sequences

1984 • 256 citations

A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences.

1981 • 243 citations

Evidence for the biochemical role of an internal sequence in yeast nuclear mRNA introns: Implications for U1 RNA and metazoan mRNA splicing

1983 • 239 citations

In vivo splicing products of the rabbit β-globin pre-mRNA

1984 • 209 citations

Deletion mapping of sequences essential for in vivo transcription of the iso-1-cytochrome c gene.

1981 • 205 citations

Expression of a beta-galactosidase gene containing the ribosomal protein 51 intron is sensitive to the rna2 mutation of yeast.

1983 • 180 citations

In vivo characterization of yeast mRNA processing intermediates

1984 • 152 citations

Evidence against a scanning model of RNA splicing.

1983 • 122 citations

A seven-base-pair deletion in an intron of the albumin gene of analbuminemic rats.

1983 • 100 citations

Two genes for ribosomal protein 51 of Saccharomyces cerevisiae complement and contribute to the ribosomes.

1984 • 87 citations

Identification of a sequence responsible for periodic synthesis of yeast histone 2A mRNA.

1982 • 83 citations

An adenovirus mutant defective in splicing RNA from early region 1A

1981 • 78 citations

Construction of a yeast actin gene intron deletion mutant that is defective in splicing and leads to the accumulation of precursor RNA in transformed yeast cells.

1982 • 58 citations

Synthetic donor and acceptor splice sites function in an RNA polymerase B (II) transcription unit.

1984 • 51 citations

Saccharomyces cerevisiae actin-Escherichia coli lacZ gene fusions: Synthetic-oligonucleotide-mediated deletion of the 309 base pair intervening sequence in the actin gene

1983 • 51 citations

A small nuclear ribonucleoprotein is required for splicing of adenoviral early RNA sequences

1981 • 35 citations