Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo

Functional Role of Type I and Type II Interferons in Antiviral Defense

1994 • 2,437 citations

CD1d-Restricted and TCR-Mediated Activation of V _α 14 NKT Cells by Glycosylceramides

1997 • 2,370 citations

NATURAL KILLER CELLS IN ANTIVIRAL DEFENSE: Function and Regulation by Innate Cytokines

1999 • 2,128 citations

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

1993 • 1,753 citations

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

1993 • 1,719 citations

NK CELL RECEPTORS

1998 • 1,666 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

Hepatitis B Virus Immunopathogenesis

1995 • 1,568 citations

Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase

1995 • 1,454 citations

MOUSE CD1-SPECIFIC NK1 T CELLS: Development, Specificity, and Function

1997 • 1,326 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Requirement for V _α 14 NKT Cells in IL-12-Mediated Rejection of Tumors

1997 • 1,226 citations

Viral Clearance Without Destruction of Infected Cells During Acute HBV Infection

1999 • 1,208 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

THE MOLECULAR BIOLOGY OF THE HEPATITIS B VIRUSES

1987 • 1,046 citations

An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans.

1994 • 1,044 citations

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Cutting Edge: Cross-Talk Between Cells of the Innate Immune System: NKT Cells Rapidly Activate NK Cells

1999 • 856 citations

CD1-Restricted T Cell Recognition of Microbial Lipoglycan Antigens

1995 • 751 citations

The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cells.

1992 • 642 citations

Crystal Structure of Mouse CD1: An MHC-Like Fold with a Large Hydrophobic Binding Groove

1997 • 629 citations

High-level hepatitis B virus replication in transgenic mice

1995 • 625 citations

Macrophages and Inflammatory Mediators in Tissue Injury

1995 • 613 citations

T cell subsets defined by expression of Lyt-1,2,3 and Thy-1 antigens. Two-parameter immunofluorescence and cytotoxicity analysis with monoclonal antibodies modifies current views.

1980 • 574 citations

Murine CD1d-Restricted T Cell Recognition of Cellular Lipids

2000 • 467 citations

Agelasphins, novel antitumor and immunostimulatory cerebrosides from the marine sponge Agelas mauritianus

1994 • 389 citations

CD1d-Restricted Immunoglobulin G Formation to GPI-Anchored Antigens Mediated by NKT Cells

1999 • 386 citations

Selective ability of mouse CD1 to present glycolipids: alpha-galactosylceramide specifically stimulates V alpha 14+ NK T lymphocytes.

1998 • 383 citations

Cutting edge: activation of NK T cells by CD1d and alpha-galactosylceramide directs conventional T cells to the acquisition of a Th2 phenotype.

1999 • 359 citations

NK1.1+ T cell receptor-alpha/beta+ cells: new clues to their origin, specificity, and function.

1995 • 355 citations

The Human Liver Contains Multiple Populations of NK Cells, T Cells, and CD3+CD56+ Natural T Cells with Distinct Cytotoxic Activities and Th1, Th2, and Th0 Cytokine Secretion Patterns

1999 • 345 citations

Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance

1986 • 344 citations

Tissue-Specific Segregation of CD1d-Dependent and CD1d-Independent NK T Cells

1999 • 332 citations

Selective induction of NK cell proliferation and cytotoxicity by activated NKT cells

2000 • 330 citations

Selective Ability of Mouse CD1 to Present Glycolipids: α-Galactosylceramide Specifically Stimulates Vα14+ NK T Lymphocytes

1998 • 319 citations

Major histocompatibility complex class I related molecules control the development of CD4+8- and CD4-8- subsets of natural killer 1.1+ T cell receptor-alpha/beta+ cells in the liver of mice.

1994 • 304 citations

Cutting Edge: Activation of NK T Cells by CD1d and α-Galactosylceramide Directs Conventional T Cells to the Acquisition of a Th2 Phenotype

1999 • 296 citations

An NK1.1+ CD4+8- single-positive thymocyte subpopulation that expresses a highly skewed T-cell antigen receptor V beta family.

1992 • 270 citations

Relative Sensitivity of Hepatitis B Virus and Other Hepatotropic Viruses to the Antiviral Effects of Cytokines

2000 • 257 citations

Agelasphins, novel α-galactosylceramides from the marine sponge Agelas mauritianus

1993 • 243 citations

Rapid Death and Regeneration of NKT Cells in Anti-CD3ε- or IL-12-Treated Mice

1998 • 233 citations

Mouse CD1 is mainly expressed on hemopoietic-derived cells.

1997 • 226 citations

Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T cell receptor bearing cells

1999 • 200 citations

Viral cross talk: intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver.

1996 • 199 citations

Murine natural killer cells contribute to the granulomatous reaction caused by mycobacterial cell walls

1999 • 196 citations

A role for CD4+ NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection.

1996 • 154 citations

Inhibition of Hepatitis B Virus Replication during Adenovirus and Cytomegalovirus Infections in Transgenic Mice

1998 • 143 citations

Structural requirements for galactosylceramide recognition by CD1-restricted NK T cells.

1998 • 138 citations

Lipid antigen presentation in the immune system; lessons learned from CD 1 d knockout mice

1999 • 121 citations

Cutting Edge: Structural Requirements for Galactosylceramide Recognition by CD1-Restricted NK T Cells

1998 • 121 citations

Nitric Oxide Inhibits Hepatitis B Virus Replication in the Livers of Transgenic Mice

2000 • 120 citations

Breaking tolerance leads to autoantibody production but not autoimmune liver disease in hepatitis B virus envelope transgenic mice.

1995 • 80 citations

Stringent V beta requirement for the development of NK1.1+ T cell receptor-alpha/beta+ cells in mouse liver.

1996 • 75 citations

Developmentally Regulated Extinction of Ly-49 Receptor Expression Permits Maturation and Selection of NK1.1+ T Cells

1998 • 64 citations