Identification of Potential Interaction Networks Using Sequence-Based Searches for Conserved Protein-Protein Interactions or “Interologs”

A comprehensive analysis of protein–protein interactions in Saccharomyces cerevisiae

2000 • 4,734 citations

Genome Sequence of the Nematode C. elegans : A Platform for Investigating Biology

1998 • 3,683 citations

A comprehensive two-hybrid analysis to explore the yeast protein interactome

2001 • 3,564 citations

A Genomic Perspective on Protein Families

1997 • 3,531 citations

Detecting Protein Function and Protein-Protein Interactions from Genome Sequences

1999 • 1,661 citations

Assigning protein functions by comparative genome analysis: Protein phylogenetic profiles

1999 • 1,556 citations

The protein–protein interaction map of Helicobacter pylori

2001 • 1,134 citations

Toward a functional analysis of the yeast genome through exhaustive two-hybrid screens

1997 • 886 citations

Toward a protein–protein interaction map of the budding yeast: A comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast proteins

2000 • 799 citations

Protein Interaction Mapping in C. elegans Using Proteins Involved in Vulval Development

2000 • 769 citations

Genome phylogeny based on gene content

1999 • 714 citations

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2000 • 633 citations

High-Throughput Yeast Two-Hybrid Assays for Large-Scale Protein Interaction Mapping

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Genome-wide analysis of vaccinia virus protein–protein interactions

2000 • 289 citations

RBF, a novel RB-related gene that regulates E2F activity and interacts with cyclin E in Drosophila.

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A protein–protein interaction map of the Caenorhabditis elegans 26S proteasome

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A genomic approach of the hepatitis C virus generates a protein interaction map

2000 • 163 citations

Open-reading-frame sequence tags (OSTs) support the existence of at least 17,300 genes in C. elegans

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Identification of a calcium channel modulator using a high throughput yeast two-hybrid screen

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Prospects for drug screening using the reverse two-hybrid system

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2000 • 42 citations

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Integrated version of reverse two-hybrid system for the postproteomic era

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The spliceosome is a dynamic ribonucleoprotein machine.

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