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STUDY OF THE PARADOXICAL EFFECTS OF SALICYLATE IN LOW, INTERMEDIATE AND HIGH DOSAGE ON THE RENAL MECHANISMS FOR EXCRETION OF URATE IN MAN *

Data up to Jan 2025

Published1959
Citations205
References46

Total Citations Per Year

Abstract

References (46)

THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN 1

1945 • 1,598 citations

Non-ionic diffusion and the excretion of weak acids and bases

1958 • 377 citations

Renal function in gout

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Effect of Sodium Lactate Infusion on Urate Clearance in Man.

1957 • 164 citations

THE RENAL MECHANISM FOR URATE EXCRETION IN MAN 1

1950 • 137 citations

Studies on the pharmacology of salicylates.

1946 • 134 citations

Salicylate and Salicyl Conjugates: Fluorimetric Estimation, Biosynthesis and Renal Excretion in Man1

1958 • 119 citations

Paradoxical Retention of Uric Acid by Uricosuric Drugs in Low Dosage.

1955 • 106 citations

The Renal Excretion of Potassium.

1948 • 91 citations

EFFECT OF BENEMID (p-[di-n-PROPYLSULFAMYL]-BENZOIC ACID) ON URATE CLEARANCE AND OTHER DISCRETE RENAL FUNCTIONS IN GOUTY SUBJECTS 1

1952 • 90 citations

A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671.

1957 • 84 citations

URINARY METABOLITES OF SODIUM SALICYLATE

1942 • 84 citations

Renal Tubular Secretion of Potassium in the Normal Dog.

1948 • 81 citations

Effect of Pyrazinamide and Pyrazinoic Acid on Urate Clearance and Other Discrete Renal Functions.

1957 • 80 citations

Zoxazolamine

1958 • 72 citations

A STUDY OF THE RETENTION OF URIC ACID DURING FASTING

1925 • 71 citations

A STUDY, BY SIMULTANEOUS CLEARANCE TECHNIQUES, OF SALICYLATE EXCRETION IN MAN. EFFECT OF ALKALINIZATION OF THE URINE BY BICARBONATE ADMINISTRATION; EFFECT OF PROBENECID 1

1955 • 70 citations

Ultrafiltrability of Plasma Urate in Man.

1953 • 60 citations

Gout, a derangement of purine metabolism.

1952 • 59 citations

THERAPEUTIC VALUE OF PROBENECID (BENEMID®) IN GOUT

1952 • 53 citations

THE EXCRETION OF SALICYLATE

1955 • 50 citations

THE METABOLISM OF THE METHYLATED PURINES

1945 • 50 citations

Benemid (p-di-n-propylsulfamyl)-benzoic acid) as uricosuric agent in chronic gouty arthritis.

1951 • 48 citations

EFFECT OF PHENYLBUTAZONE (3,5 DIOXO-1,2-DIPHENYL-4-n-BUTYLPYRAZOLIDINE) ON RENAL CLEARANCE OF URATE AND OTHER DISCRETE RENAL FUNCTIONS IN GOUTY SUBJECTS 1

1953 • 41 citations

THE METABOLISM OF THE METHYLATED PURINES

1945 • 39 citations

Evaluation of Uricosuric Agents in Chronic Gout

1957 • 37 citations

Results of a clinical trial of g‐28315, a sulfoxide analog of phenylbutazone, as a uricosuric agent in gouty subjects

1958 • 34 citations

Some recent advances in the study of uric acid metabolism and gout.

1951 • 32 citations

EFFECT OF CARBOHYDRATE AND FAT IN THE DIET ON URIC ACID EXCRETION

1939 • 26 citations

Quantitative analysis of uric acid in blood and urine; methods and interpretation.

1957 • 24 citations

The Kidney

1954 • 24 citations

Value of Uricosuric Agents and in Particular of G.28 315 in Gout

1958 • 24 citations

THIOSULPHATE CLEARANCE IN PREGNANCY

1950 • 23 citations

The influence of urinary pH on the renal excretion of salicyl derivatives during aspirin therapy.

1950 • 22 citations

The Diagnosis of Gout

1958 • 18 citations

Renal regulation of uric acid excretion in normal and gouty man; modification by uricosuric agents.

1958 • 18 citations

On the Excretion of Salicylic acid in Man: (A Preliminary Report)

1949 • 16 citations

Sodium Salicylate and Probenecid in the Treatment of Chronic Gout : Assessment of Their Relative Effects in Lowering Serum Uric Acid Levels

1954 • 16 citations

Inhibition of the uricosuric action of benemid by salicylate.

1955 • 15 citations

EFFECT OF A PHENYLBUTAZONE ANALOG (4-[PHENYLTHIOETHYL]-1,2-DIPHENYL 3,5-PYRAZOLIDINEDIONE) ON URATE CLEARANCE AND OTHER DISCRETE RENAL FUNCTIONS IN GOUTY SUBJECTS. EVALUATION AS URICOSURIC AGENT 1

1956 • 15 citations

Electromigration on Filter Paper of Uric Acid from Serum and Synovial Fluid

1958 • 12 citations

THE EFFECT OF SODIUM BICARBONATE ON THE RENAL EXCRETION OF SALICYLATE

1948 • 12 citations

FACTORS INFLUENCING PLASMA CONCENTRATIONS OF SALICYLATE

1948 • 11 citations

The effect of sodium bicarbonate on the renal excretion of salicylate

1949 • 7 citations

The Effect of Salicylic Acid and Acetylsalicylic Acid on Uric Acid Excretion and Plasma Uric Acid Concentration in the Normal Human Subject.

1955 • 7 citations

Probenecid and salicylates: the question of interaction in terms of penicillin excretion.

1955 • 4 citations

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STUDY OF THE PARADOXICAL EFFECTS OF SALICYLATE IN LOW, INTERMEDIATE AND HIGH DOSAGE ON… (1959) – Journal of Clinical Investigation | Metascience Observatory Explorer