No Evidence for an Effect of the CCR5 Δ32/+ and CCR2b 64I/+ Mutations on Human Immunodeficiency Virus (HIV)‐1 Disease Progression among HIV‐1–Infected Injecting Drug Users

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

1996 • 4,184 citations

Identification of a major co-receptor for primary isolates of HIV-1

1996 • 3,649 citations

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1996 • 3,189 citations

Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection

1996 • 3,106 citations

Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8 ⁺ T Cells

1995 • 2,890 citations

Resistance to HIV-1 infection in Caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

1996 • 2,883 citations

Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene

1996 • 2,502 citations

A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors

1996 • 1,868 citations

The role of a mutant CCR5 allele in HIV–1 transmission and disease progression

1996 • 1,364 citations

Contrasting Genetic Influence of CCR2 and CCR5 Variants on HIV-1 Infection and Disease Progression

1997 • 899 citations

Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene

1996 • 701 citations

Information Bounds and Nonparametric Maximum Likelihood Estimation

1992 • 688 citations

HIV Coreceptor Downregulation as Antiviral Principle: SDF-1α–dependent Internalization of the Chemokine Receptor CXCR4 Contributes to Inhibition of HIV Replication

1997 • 564 citations

The role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease progression

1997 • 454 citations

A chemokine receptor CCR2 allele delays HIV-1 disease progression and is associated with a CCR5 promoter mutation

1998 • 397 citations

HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay

1992 • 353 citations

HIV-1-resistance phenotype conferred by combination of two separate inherited mutations of CCR5 gene

1998 • 274 citations

Association between CCR5 Genotype and the Clinical Course of HIV-1 Infection

1997 • 268 citations

Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals

1997 • 238 citations

A one-tube quantitative HIV-1 RNA NASBA nucleic acid amplification assay using electrochemiluminescent (ECL) labelled probes

1994 • 217 citations

C-C chemokines, pivotal in protection against HIV type 1 infection

1998 • 206 citations

The Iterative Convex Minorant Algorithm for Nonparametric Estimation

1998 • 118 citations

Predictors of Mortality in the Amsterdam Cohort of Human Immunodeficiency Virus (HIV)-positive and HIV-negative Drug Users

1996 • 103 citations

Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function.

1996 • 88 citations

Role of CCR2 Genotype in the Clinical Course of Syncytium‐Inducing (SI) or Non‐SI Human Immunodeficiency Virus Type 1 Infection and in the Time to Conversion to SI Virus Variants

1998 • 65 citations

Pre-AIDS mortality from natural causes associated with HIV disease progression

1997 • 64 citations

Comparison of progression and non-progression in injecting drug users and homosexual men with documented dates of HIV-1 seroconversion

1997 • 59 citations

Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men

1995 • 58 citations

Longer survival after HIV infection for injecting drug users than for homosexual men

1997 • 55 citations

The Iterative Convex Minorant Algorithm for Nonparametric Estimation

1998 • 54 citations

Frequent injecting impairs lymphocyte reactivity in HIV-positive and HIV-negative drug users

1991 • 53 citations

Evidence for HIV Type 1 Strains of U.S. Intravenous Drug Users as Founders of AIDS Epidemic among Intravenous Drug Users in Northern Europe

1996 • 51 citations

Tracking of markers and onset of disease among HIV‐1 seroconverters

1993 • 38 citations

Differences in Progression to AIDS between Injection Drug Users and Homosexual Men with Documented Dates of Seroconversion

1996 • 38 citations

New evidence to reconcile in vitro and epidemiologic data on the possible role of heroin on CD4+ decline among HIV-infected injecting drug users

1999 • 27 citations

Comparison of progression and non-progression in injecting drug users and homosexual men with documented dates of HIV-1 seroconversion Maria Prins and Paul J. Veugelers for the European Seroconverter Study and the Tricontinental Seroconverter Study

1997 • 17 citations