Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors.

p53 Mutations in Human Cancers

1991 • 8,133 citations

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.

1990 • 1,080 citations

The essentials of DNA methylation

1992 • 960 citations

High levels of De Novo methylation and altered chromatin structure at CpG islands in cell lines

1990 • 709 citations

Loss of alleles of loci on the short arm of chromosome 3 in renal cell carcinoma

1987 • 638 citations

X-chromosome inactivation and cell memory

1992 • 329 citations

Dynamic mutations: A new class of mutations causing human disease

1992 • 315 citations

The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia.

1988 • 197 citations

Molecular analysis of genetic changes in the origin and development of renal cell carcinoma.

1991 • 181 citations

Fragile sites in human chromosomes as regions of late-replicating DNA

1987 • 158 citations

Molecular and cellular characterization of human renal cell carcinoma cell lines.

1992 • 106 citations

Isolation and mapping of a polymorphic DNA sequence (pYNZ22) on chromosome 17p [D17S30]

1988 • 93 citations

DNA hypermethylation is associated with 17p allelic loss in neural tumors.

1993 • 75 citations

Tumor Suppressor Gene Allelic Loss in Human Renal Cancers

1993 • 51 citations

Allelic losses at chromosome 17p in human renal cell carcinoma are inversely related to allelic losses at chromosome 3p.

1992 • 37 citations

A gene near the D3F15S2 site on 3p is expressed in normal human kidney but not or only at a severely reduced level in 11 of 15 primary renal cell carcinomas (RCC).

1990 • 31 citations