Impairment in proliferation, lymphokine production and frequency distribution of mitogen-responsive and interleukin-2-producing cells in Hodgkin's disease

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Limiting dilution assays for the determination of immunocompetent cell frequencies. I. Data analysis.

1981 • 1,281 citations

Direct demonstration of the clonogenic potential of every human peripheral blood T cell. Clonal analysis of HLA-DR expression and cytolytic activity.

1983 • 351 citations

Sequential expression of protooncogenes during lectin-stimulated mitogenesis of normal human lymphocytes.

1986 • 335 citations

Limiting Dilution Analysis of Cells in the Immune System

1980 • 325 citations

Sequential expression of genes involved in human T lymphocyte growth and differentiation.

1985 • 291 citations

Regulation of human interleukin-2 gene: Functional DNA sequences in the 5′ flanking region for the gene expression in activated T lymphocytes

1986 • 288 citations

Interleukin-2 Induction of T-Cell G ₁ Progression and c- myb Expression

1986 • 248 citations

Interferons with Special Emphasis on the Immune System

1983 • 211 citations

Limiting dilution analysis of alloantigen-reactive T lymphocytes. I. Comparison of precursor frequencies for proliferative and cytolytic responses.

1979 • 132 citations

Limiting Dilution Analysis of Alloantigen-Reactive T Lymphocytes

1979 • 111 citations

Frequency and surface phenotype of human T lymphocytes producing interleukin 2. Analysis by limiting dilution and cell cloning

1985 • 75 citations

Interferon‐γ is not an antiviral, but a growth‐promoting factor for t lymphocytes

1988 • 63 citations

Lecture Notes on Medical Statistics.

1988 • 57 citations

Association of an interleukin abnormality with the T cell defect in Hodgkin's disease

1984 • 56 citations

Enhancing effect of IFN-gamma on helper T cell activity and IL 2 production.

1985 • 49 citations

Estimation by limiting dilution analysis of human IL 2-secreting T cells: detection of IL 2 produced by single lymphokine-secreting T cells.

1986 • 49 citations

Aquanititave semimicro, semiautomated colorimetric assay for interferon.

1977 • 43 citations

An improved colorimetric assay for T cell cytotoxicity in vitro

1984 • 39 citations

Implications of persistent T cell abnormalities for the etiology of Hodgkin's disease.

1982 • 28 citations

Impaired interleukin regulation of the phytohemagglutinin response in Hodgkin's disease

1985 • 26 citations

Independent regulation of IFN-gamma and tumor necrosis factor by IL-1 in human T helper cells.

1990 • 25 citations

Impaired T- and B-cell functions in patients with Hodgkin's disease

1987 • 24 citations

Defect in lectin-induce interleukin 2 (IL-2) production by peripheral blood lymphocytes of patients with Hodgkin's Disease

1985 • 23 citations

The molecular basis of immune cytokine action.

1989 • 21 citations

Demonstration of inhibitory factors affecting cell-mediated immunity in patients with Hodgkin's disease

1980 • 14 citations

Lecture Notes on Medical Statistics

1979 • 12 citations

Impairment of T Lymphocyte Colony Formation in Hodgkin’s Disease: Effect of Soluble Inhibitory Factors on Normal T Lymphocyte Colony Formation Potential

1983 • 12 citations

Affinity of IL-2 receptors and proliferation of mitogen activated lymphocytes in Hodgkin's disease

1990 • 6 citations

Impaired proliferative response and low interleukin-2 production in patients with lymphoma.

1987 • 6 citations

Effect of exogenous interleukins on in vitro responses of T lymphocytes from patients with Hodgkin disease.

1987 • 5 citations

Production of interleukin-2 and expression of tac antigen in Hodgkin disease.

1987 • 5 citations

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