A systematic review of analytical methods used to study subgroups in (individual patient data) meta-analyses

Measuring inconsistency in meta-analyses

2003 • 53,662 citations

Systematic Reviews in Health Care : Meta-Analysis in Context

2000 • 2,282 citations

Screening for breast cancer with mammography

2013 • 1,806 citations

Epidemiology: An introduction

2016 • 1,570 citations

Systematic Reviews in Health Care. Meta-analysis in Context.

2002 • 1,441 citations

Thrombolysis for acute ischaemic stroke

2014 • 1,323 citations

Breast Cancer Screening: A Summary of the Evidence for the U.S. Preventive Services Task Force

2002 • 1,139 citations

Effect of Alpha-Interferon Treatment in Patients with Hepatitis B e Antigen-Positive Chronic Hepatitis B

1993 • 1,011 citations

Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much?

2004 • 994 citations

Analysis and Interpretation of Treatment Effects in Subgroups of Patients in Randomized Clinical Trials

1991 • 954 citations

Palliative chemotherapy for advanced colorectal cancer: systematic review and meta-analysis

2000 • 943 citations

A Consumer's Guide to Subgroup Analyses

1992 • 910 citations

Epidemiology: An Introduction

2002 • 904 citations

Donepezil for dementia due to Alzheimer's disease

2018 • 863 citations

Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed

2002 • 831 citations

Meta-analysis of the literature or of individual patient data: is there a difference?

1993 • 752 citations

Low-molecular-weight heparin versus standard heparin in general and orthopaedic surgery: a meta-analysis

1992 • 679 citations

Subgroup analyses in randomized trials: risks of subgroup-specific analyses;

2004 • 637 citations

Chemotherapy in locally advanced nasopharyngeal carcinoma: An individual patient data meta-analysis of eight randomized trials and 1753 patients

2005 • 619 citations

Efficacy and tolerability of venlafaxine compared with selective serotonin reuptake inhibitors and other antidepressants: A meta-analysis

2002 • 544 citations

Subgroup analyses in randomised controlled trials: quantifying the risks of false-positives and false-negatives

2001 • 542 citations

The Continuing Unethical Conduct of Underpowered Clinical Trials

2002 • 533 citations

Meta-analysis of individual patient data from randomized trials: a review of methods used in practice

2005 • 522 citations

Does Locoregional Radiation Therapy Improve Survival in Breast Cancer? A Meta-Analysis

2000 • 514 citations

To IPD or not to IPD?

2002 • 511 citations

Effectiveness of antibiotic prophylaxis in critically ill adult patients: systematic review of randomised controlled trials

1998 • 455 citations

Effect of Angiotensin-Converting Enzyme Inhibitors on the Progression of Nondiabetic Renal Disease

1997 • 436 citations

Allogeneic Peripheral Blood Stem-Cell Compared With Bone Marrow Transplantation in the Management of Hematologic Malignancies: An Individual Patient Data Meta-Analysis of Nine Randomized Trials

2005 • 430 citations

Individual patient‐ versus group‐level data meta‐regressions for the investigation of treatment effect modifiers: ecological bias rears its ugly head

2002 • 413 citations

The Additional Value of Chemotherapy to Radiotherapy in Locally Advanced Nasopharyngeal Carcinoma: A Meta-Analysis of the Published Literature

2004 • 404 citations

Effects of angiotensin converting enzyme inhibitors and angiotensin II receptor antagonists on mortality and renal outcomes in diabetic nephropathy: systematic review

2004 • 381 citations

A comparison of summary patient-level covariates in meta-regression with individual patient data meta-analysis

2002 • 378 citations

An evidence based approach to individualising treatment

1995 • 369 citations

Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care

2004 • 360 citations

Efficacy and Safety of Cholinesterase Inhibitors in Alzheimer’s Disease: A Meta-analysis

2022 • 321 citations

Concomitant radio-chemotherapy based on platin compounds in patients with locally advanced non-small cell lung cancer (NSCLC): A meta-analysis of individual data from 1764 patients

2006 • 292 citations

Prophylactic cranial irradiation in small cell lung cancer: a systematic review of the literature with meta-analysis

2001 • 282 citations

Choosing a concomitant chemotherapy and radiotherapy regimen for squamous cell head and neck cancer: A systematic review of the published literature with subgroup analysis

2001 • 277 citations

Implantable Cardioverter Defibrillators in Primary and Secondary Prevention

2003 • 265 citations

Meta‐analysis of continuous outcome data from individual patients

2001 • 263 citations

A multilevel model framework for meta-analysis of clinical trials with binary outcomes

2000 • 259 citations

Randomized trials of radiotherapy alone versus combined chemotherapy and radiotherapy in stages IIIa and IIIb nonsmall cell lung cancer: A meta‐analysis

1996 • 248 citations

Imputations of Missing Values in Practice: Results from Imputations of Serum Cholesterol in 28 Cohort Studies

2004 • 235 citations

Meta-regression detected associations between heterogeneous treatment effects and study-level, but not patient-level, factors

2004 • 231 citations

Heparin, low molecular weight heparin and physical methods for preventing deep vein thrombosis and pulmonary embolism following surgery for hip fractures

2002 • 230 citations

Effect of early intervention with sumatriptan on migraine pain: Retrospective analyses of data from three clinical trials

2000 • 222 citations

Early Start of Adjuvant Chemotherapy May Improve Treatment Outcome for Premenopausal Breast Cancer Patients With Tumors not Expressing Estrogen Receptors

2000 • 198 citations

Multivariable risk prediction can greatly enhance the statistical power of clinical trial subgroup analysis

2006 • 196 citations

One-year outcomes of coronary artery bypass graft surgery versus percutaneous coronary intervention with multiple stenting for multisystem disease: A meta-analysis of individual patient data from randomized clinical trials

2005 • 172 citations

Interferon and Ribavirin vs Interferon Alone in the Re-treatment of Chronic Hepatitis C Previously Nonresponsive to Interferon

2001 • 163 citations

The rate of progression of renal disease may not be slower in women compared with men: a patient-level meta-analysis

2003 • 161 citations

Investigating heterogeneity in an individual patient data meta-analysis of time to event outcomes

2005 • 158 citations

Comparative efficacy between venlafaxine and SSRIs: a pooled analysis of patients with depression

2002 • 152 citations

Comparison of Effect Estimates from a Meta-Analysis of Summary Data from Published Studies and from a Meta-Analysis Using Individual Patient Data for Ovarian Cancer Studies

1997 • 150 citations

Comparison of Meta-Analysis Versus Analysis of Variance of Individual Patient Data

1998 • 139 citations

A Comparison of Meta-analytic Results Using Literature vs Individual Patient Data

1995 • 134 citations

Topical NSAIDs for acute pain: a meta-analysis

2004 • 134 citations

Analysis and interpretation of treatment effects in subgroups of patients in randomized clinical trials

1991 • 129 citations

Assessing the potential for bias in meta-analysis due to selective reporting of subgroup analyses within studies

2000 • 117 citations

Risedronate decreases fracture risk in patients selected solely on the basis of prior vertebral fracture

2004 • 105 citations

Survival benefit of chemotherapy in metastatic colorectal cancer: a meta-analysis of randomized controlled trials

2000 • 104 citations

Early or Deferred Zidovudine Therapy in HIV-Infected Patients without an AIDS-Defining Illness

1995 • 93 citations

Meta‐analysis of ordinal outcomes using individual patient data

2001 • 89 citations

CD4 cell count as a surrogate endpoint in HIV clinical trials

1998 • 77 citations

Streptokinase in Acute Ischemic Stroke: An Individual Patient Data Meta-Analysis

2000 • 76 citations

A Meta-analysis of Trials on Aldose Reductase Inhibitors in Diabetic Peripheral Neuropathy

1996 • 73 citations

Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments

1997 • 63 citations

Risedronate for the prevention and treatment of postmenopausal osteoporosis.

2003 • 59 citations

Incommunicable Knowledge? Interpreting and Applying the Results of Clinical Trials and Meta-Analyses

1998 • 56 citations

Meta-Analysis of Rizatriptan Efficacy in Randomized Controlled Clinical Trials

2001 • 54 citations

Adjuvant radiotherapy for breast cancer: effects of longer follow-up

2004 • 48 citations

Problems in the medical interpretation of overviews

1987 • 47 citations

Individual Patient- versus Literature-Based Meta-analysis of Survival Data

2001 • 45 citations

The role of 5-fluorouracil dose in the adjuvant therapy of colorectal cancer

1996 • 42 citations

Systematic reviews of published evidence: Miracles or minefields?

1998 • 42 citations

Percutaneous transluminal coronary angioplasty with stents versus coronary artery bypass grafting for people with stable angina or acute coronary syndromes

2005 • 39 citations

The Efficacy of Tolrestat in the Treatment of Diabetic Peripheral Neuropathy: A meta-analysis of individual patient data

1996 • 28 citations

Survival after HLA-identical allogeneic peripheral blood stem cell and bone marrow transplantation for hematologic malignancies: meta-analysis of randomized controlled trials

2003 • 27 citations

Ribavirin with or without alpha interferon for chronic hepatitis C

2002 • 27 citations

From science to practice. Meta-analyses using individual patient data are needed

1995 • 24 citations

A comparison of meta-analytic results using literature vs individual patient data. Paternal cell immunization for recurrent miscarriage

1995 • 20 citations